Person: GÜL, BURCU
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Publication Metadata only Search for the G spot: microvessel and nerve mapping of the paraurethral anterior vaginal wall(2020-06-01T00:00:00Z) AYDIN, SERDAR; SÖNMEZ, FATMA CAVİDE; GÖKMEN KARASU, AYŞE FİLİZ; GÜL, Burcu; Arioglu, Cagri; AYDIN, SERDAR; SÖNMEZ, FATMA CAVİDE; GÖKMEN KARASU, AYŞE FİLİZ; GÜL, BURCUIntroduction and hypothesis Orgasm and other sexual responses such as pain, arousal and lubrication may be mediated by nerve fibers and vessels in the lamina propria and muscularis of the vaginal wall, in which case the number of nerve fibers and vessels would be associated with sexual functions. The aim of the study is to map the distribution of nerves and vessels in the anterior vaginal wall along the paraurethral region in a systematic fashion. Methods Specimens were taken from women with anterior vaginal wall prolapse undergoing colporrhaphy anterior repair. All specimens were mapped in a standard way starting 15 mm proximal to the external urethral orifice. Selected blocks of samples were immunohistochemically stained: actin, smooth muscle Ab-1 and S100 Protein Ab-1. The numbers of microvessels and nerves in the lamina propria and muscularis were counted in five consecutive high-power fields of a light microscope. Pairwise comparisons of proximal, distal, right and left paravaginal microvessel and nerve fiber density were analyzed with paired-sample t-test or Wilcoxon signed-rank test. Results Vaginal nerve fibers in the lamina propria and muscularis have a fairly even distribution in the anterior vaginal wall. Vaginal small vessel vascularization and microvascularization are also evenly distributed, with no concentrated site along the paraurethral region of the anterior vaginal wall. Conclusions Nerve fiber, nerve bundle, microvessel and small vessel densities in the lamina propria and muscularis were fairly regular, with no concentrated site on the paraurethral region of the anterior vaginal wall.Publication Metadata only Long-term follow-up the gastric adenocarcinoma patients in terms of post-operative outcomes associated with notch signal pathways and target proteins(2019-10-01T00:00:00Z) Saraç, Elif Yaprak; Hasbahçeci, Mustafa; Ünver, Nurcan; Çoban, Ganime; Gül, Burcu; Akçakaya, Adem; ÇOBAN, GANİME; GÜL, BURCU; AKÇAKAYA, ADEMPublication Metadata only ASSOCIATION OF NOTCH SIGNAL PATHWAYS AND TARGET PROTEINS, AND MATRIX METALLOPROTEINASES WITH PROGRESSION, INVASION AND METASTASIS OF GASTRIC ADENOCARCINOMA TUMORS(2019-09-21T00:00:00Z) Akçakaya, Adem; Hasbahçeci, Mustafa; Saraç, Elif Yaprak; Akçakaya, Fatma Betül; Ünver, Nurcan; Çoban, Ganime; Gül, Burcu; Kotil, Tuğba; Özdemir, İlkay; Solakoğlu, Seyhun; AKÇAKAYA, ADEM; ÇOBAN, GANİME; GÜL, BURCUPublication Metadata only EFFECT OF STAT3 STATUS ON RAS & RAF MUTATION IN PATIENTS WITH METASTATIC COLON CARCINOMA(2023-10-29) Geçer M.; Turna S.; Gül B.; Gücin Z.; GEÇER, MELİN; TURNA, SEVAL; GÜL, BURCU; GÜCİN, ZÜHAL