Person: KESKİN, YAŞAR
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Publication Metadata only The effect of fibromyalgia on bone mineral density in patients with hypothyroidism(2019-05-01T00:00:00Z) TAŞPINAR, ÖZGÜR; KESKİN, YAŞAR; kiziltan, huriye; ÇAMLI, AHMET ADİL; URKMEZ, BERNA; mutluer, ahmet serdar; AYDIN, TEOMAN; eriş, ali h; KESKİN, YAŞAR; AYDIN, TEOMAN; ÇAMLI, AHMET ADİLPublication Open Access The impact of COVID-19 on familial Mediterranean fever: a nationwide study(2021-05-25T00:00:00Z) Günendi, Zafer; Yurdakul, Fatma Gül; Bodur, Hatice; Cengiz, Ahmet Kıvanç; Uçar, Ülkü; Çay, Hasan Fatih; Şen, Nesrin; Keskin, Yaşar; Gürer, Gülcan; Melikoğlu, Meltem Alkan; Altıntaş, Duygu; Deveci, Hülya; Baykul, Merve; Nas, Kemal; Çevik, Remzi; Karahan, Ali Yavuz; Toprak, Murat; Ketenci, Sertaç; Nayimoğlu, Mehmet; Sezer, İlhan; Demir, Ali Nail; Ecesoy, Hilal; Duruöz, Mehmet Tuncay; Yurdakul, Ozan Volkan; Sarıfakıoğlu, Ayşe Banu; Ataman, Şebnem; KESKİN, YAŞAR; YURDAKUL, OZAN VOLKANThe study aimed to evaluate the impact of the coronavirus disease 2019 (COVID-19) in patients with familial Mediterranean fever (FMF) and to assess the relationships between FMF characteristics and severe COVID-19 outcomes such as hospitalization. The study was planned within a national network of 21 different centers. Demographics, FMF-related clinical and genetic characteristics, and COVID-19 outcomes were obtained. A total of 822 patients with FMF (mean age of 36 years) were included in the study. Fifty-nine of them (7%) had a COVID-19 diagnosis confirmed by real-time PCR test or chest CT findings. Most FMF patients with COVID-19 (58) had mild and moderate disease activity. All patients were on colchicine treatment. However, 8 of them (13.6%) were not compliant with colchicine use and 9 of them (15.3%) were colchicine resistant. Twelve FMF patients with COVID-19 were hospitalized. There were 4 patients requiring oxygen support. COVID-19 related complications were observed in 2 patients (1 thromboembolism, 1 acute respiratory distress syndrome). Hospitalized COVID-19 patients with FMF were older than non-hospitalized patients (median ages: 51 and 31 years, respectively; p: 0.002). Other FMF-related characteristics were similar between the groups. FMF-related characteristics were not found to be associated with poor outcomes in COVID-19. Thus, FMF may not be a risk factor for poor COVID-19 outcomes.Publication Metadata only Clinical course and prognostic factors of COVID-19 infection in patients with chronic inflammatory-rheumatic disease: A retrospective, case-control study(2022-09-01T00:00:00Z) Nas, Kemal; Guclu, Ertugrul; KESKİN, Yaşar; Dilek, Gamze; Unan, Mehtap Kalcik; Can, Nurselin; Tekeoglu, Ibrahim; Kamanli, Ayhan; KESKİN, YAŞARObjectives: This study aims to investigate the prognosis of novel coronavirus disease-2019 (COVID-19) infection in patients with the chronic inflammatory-rheumatic disease and evaluate the effects of immunosuppressive drugs on the prognosis, clinical characteristics, laboratory findings and hospitalization periods of the rheumatic patients with COVID-19 infection. Patients and methods: Between April 2020 and March 2021, a total of 101 patients (30 males, 71 females; mean age: 48±14.4 years; range, 46 to 48 years) with the rheumatic diseases diagnosed with COVID-19 infection were included. A total of 102 age- and sex-matched patients (35 males, 67 females; mean age: 44±14.4 years; range, 28 to 44 years) who were diagnosed with COVID-19 infection and had no history of rheumatic disease in the same period were included as the control group. Data including demographic characteristics of the patients, presence of any symptoms of COVID-19 disease, laboratory data at the time of diagnosis, and treatments administered were collected. Results: The rate of hospitalization was higher in 38 (37%) patients without rheumatic diseases than in 31 (31%) patients with rheumatic diseases (p=0.324). The rate of lung infiltration on radiographic examination was higher in patients without rheumatic diseases (40% vs. 49%) (p=0.177). COVID-19 infection symptoms such as anosmia 45 (45%), ageusia 51 (50%), shortness of breath 45(45%), nausea 29 (29%), vomiting 16 (16%), diarrhea 25 (25%) and myalgia-arthralgia 81 (80%) were higher in patients with rheumatic diseases. In terms of laboratory values, lymphocyte count (p=0.031) was statistically higher in patients without rheumatic diseases. Hydroxychloroquine (35%), oseltamivir 10 (10%), antibiotics 27 (26%), acetylsalicylic acid 52 (51%), and supplementary oxygen 25 (25%) treatments which used to cure COVID 19 infection were administered more in patients without rheumatic diseases. The number of treatments administered was higher in patients without rheumatic diseases (p<0.001). Conclusion: Patients with the chronic inflammatory-rheumatic disease have more symptoms due to COVID-19 infection, but the disease course is not poor and hospitalization rates are lower.Publication Metadata only Comparing the efficacy of exercise, internal and external shoe modification in pes planus: A clinical and pedobarographic study(2017-01-01T00:00:00Z) TASPINAR, Ozgur; Kabayel, Derya Demirbag; Ozdemir, Ferda; Tuna, Hakan; Keskin, YAŞAR; MERCİMEK, Oznur Berke; Sut, Necdet; Yavuz, Selcuk; Tuna, Filiz; KESKİN, YAŞARPes planus is a condition that can cause pain along the innerfoot due to the absence or abnormal depression of the longitudinal arch. There are few studies available that compare therapy modalities used in these patients. In our study, those treated with conservative therapies-internal and external shoe modifications and pes planus exercises -were compared clinically and pedobarographyically. 60 pes planus patients were included in the study. In the first group; internal modification was performed by placing a medial longitudinal arch support inside the shoe. In the second group, external shoe modification was performed using the Thomas heel. In the third group of patients however, only an exercise program was executed. The patients- foot pain levels, functional asssessment, satisfaction and quality of life were recorded. Pedobarography was used in measuring both static and dynamic plantar pressure. Assessments were carried out at baseline and at the end of the first and third months respectively where intra-and inter-group comparisons were performed. Each group was composed of 20 subjects. While improvement in terms of foot pain, foot function index and quality of life was observed in all the study groups (p < 0.05), the most improvement was observed in the group of patients treated with internal modification (p < 0.016). This was followed by the external modification and the exercise groups respectively. No difference was observed between the internal and external modification groups in terms of patient satisfaction. Cross-sectionally; clinical assessments, pedobarographic analysis were correlated. The changes observed after static and dynamic pedobarographic studies were not significantly different between the study groups. At the end of the study it was observed that internal modification yielded the most significant clinical improvement. In the literature, there are limited publications comparing the conservative treatments with each other. In this study we aimed to compare the conservative treatments for flatfoot.Publication Metadata only Association between nutritional status and Modic classification in degenerative disc disease(2016-04-01) TASPINAR, Ozgur; Seyithanoglu, Hakan; CAMLI, Adil; KIZILTAN, Huriye; HOCAOGLU, Ilknur Turk; Aydin, TEOMAN; Keskin, YAŞAR; Ozder, ACLAN; Eris, ALİ HİKMET; DENIZLI, Ebru; KEPEKCI, Muge; SEYİTHANOĞLU, MEHMET HAKAN; AYDIN, TEOMAN; ERİŞ, ALİ HİKMET; ÖZDER, ACLAN; KESKİN, YAŞAR[Purpose] This study was conducted to examine the association between Modic classification and the eating habits in patients with degenerative disc disease (DDD) and to determine the influence of nutrition on disease severity. [Subjects and Methods] Sixty patients with DDD visiting a low back pain outpatient clinic were enrolled. Through face-to-face interviews, they completed questionnaires regarding their demographics, disease activity, smoking and alcohol use, concomitant diseases, disease duration, and nutritional status. Exclusion criteria were age 65 years, other comorbidities, missing MRI data, and inability to speak Turkish. [Results] Forty patients were finally included in the study. The frequency with which they consumed water, salt, fast food, eggs, milk, yogurt, cheese, whole wheat bread, white bread, butter, and margarine was recorded. A weak negative correlation was observed between the Modic types and fish and egg consumption. [Conclusion] Modic changes, which indicate the severity of DDD, seem to be correlated to patients- dietary habits. However, studies with comparison groups and larger samples are needed to confirm our promising results before any cause-and-effect relationship can be proposed.Publication Metadata only Correlation between sitting duration and position and lumbar pain among office workers(2021-02-01T00:00:00Z) KEPEKÇİ, MÜGE; AYDIN, TEOMAN; KESKİN, YAŞAR; ÜRKMEZ, BERNA; KESKİN, YAŞAR; AYDIN, TEOMANPublication Metadata only THE IMPACT OF SOCIOECONOMIC STATUS ON CLINICAL PARAMETERS IN FEMALE PSA PATIENTS(2021-09-01T00:00:00Z) Tekeoglu, I.; Nas, K.; KESKİN, Yaşar; Kilic, E.; Sargin, B.; Kasman, Acer S.; Alkan, H.; Sahin, N.; Cengiz, G.; Cuzdan, N.; Gezer, Albayrak; Keskin, D.; Mulkoglu, C.; Resorlu, H.; Ataman, S.; Hasturk, Bal A.; Duruoz, Tuncay M.; Kucukakkas, O.; Yurdakul, Volkan O.; Melikoglu, Alkan M.; Ayhan, Figen F.; Baykul, M.; Bodur, H.; Calis, M.; Capkin, E.; Devrimsel, G.; Ecesoy, H.; Gok, K.; Hizmetli, S.; Kamanli, A.; Kutluk, O.; Sen, N.; Sendur, Faruk O.; Toprak, M.; Tolu, S.; Tuncer, T.; KESKİN, YAŞAR; YURDAKUL, OZAN VOLKANPublication Metadata only Evaluation of hepatitis serology and frequency of viral reactivation in patients with inflammatory arthritis receiving biologic agents: a multicenter observational study(2022-09-01T00:00:00Z) ÇAPKIN, ERHAN; YAZICI, ALİ; KARKUCAK, MURAT; Durmaz, Yunus; Toprak, Murat; ATAMAN, ŞEBNEM; Sahin, Nilay; Cuzdan, Nihan; Kasapoglu Aksoy, Meliha; Onder, Mustafa Erkut; Serdaroglu Beyazal, Munevver; Mesci, Nilgun; Baykul, Merve; Alkan Melikoglu, Meltem; Alkan, Hakan; Dulgeroglu, Deniz; Cengiz, Ahmet Kivanc; Nas, Kemal; Balevi Batur, Elif; Caliskan Uckun, Asli; Deveci, Hulya; Erol, Kemal; Albayrak Gezer, Ilknur; Akgol, Gurkan; Duruoz, Mehmet Tuncay; Kucukakkas, Okan; Sarikaya, Selda; Rezvani, Aylin; Atan, Tugba; Gogus, Feride; Caglayan, Gokhan; KESKİN, Yaşar; Bulut Keskin, Ayse Selcen; Oz, Nuran; Yilmaz, Gurdal; KESKİN, YAŞARTo evaluate of hepatitis serology and reactivation frequency in patients with rheumatic disease receiving biologic agents. Our study included patients with inflammatory rheumatic diseases from 23 centers, who were followed up with biological therapy. Demographic and clinical characteristics of the patients, duration of drug use and hepatitis serology and the state of viral reactivation were analyzed. A total of 4060 patients, 2095 being males, were included in our study. Of the patients, 2463 had Ankylosing Spondylitis (AS), 1154 had Rheumatoid Arthritis (RA), 325 had Psoriatic Arthritis (PsA), and 118 had other inflammatory rheumatic diseases. When the viral serology of the patients was evaluated, 79 patients (2%) who were identified as HBs Ag positive, 486 (12%) patients who were HBs Ag negative and anti-HBc IgG positive and 20 patients (0.5%) who were anti-HCV positive. When evaluated on a disease-by-disease basis, the rate of HBsAg was found to be 2.5% in RA, 2% in AS and 0.9% in PsA. Viral reactivation was detected in 13 patients while receiving biologic agents. HBs Ag was positive in nine patients with reactivation and negative in four patients. Anti-HBc IgG, however, was positive. Six of these patients had AS, four had RA, and three had PsA. The development of hepatitis reactivation in 11.4% of HBs Ag positive patients and 0.82% of anti-HBc IgG positive patients due to the use of biologic agents is an important problem for this group of patients. Antiviral prophylaxis is recommended to be started especially in patients who are HBs Ag positive and who are using biologic agents due to viral reactivation. Therefore, it is important to carry out hepatitis screenings before biologic agent treatment and to carefully evaluate the vaccination and prophylaxis requirements.Publication Metadata only Comparison Between Kinesio Taping And Extracorporeal Shockwave Therapy in Treatment of Subacromial Impingement Syndrome(2019-01-01T00:00:00Z) KEPEKCI, MÜGE; ÜRKMEZ, BERNA; KESKİN, YAŞAR; AYDIN, TEOMAN; ÜRKMEZ, BERNA; KESKİN, YAŞAR; AYDIN, TEOMANPublication Metadata only Coexistence of fibromyalgia and metabolic syndrome in females: The effects on fatigue, clinical features, pain sensitivity, urinary cortisol and norepinephrine levels: A cross-sectional study(2021-03-01T00:00:00Z) KESKİN, Yaşar; Nas, Kemal; Kilic, Erkan; Sargin, Betul; Kasman, Sevtap Acer; Alkan, Hakan; Sahin, Nilay; CENGİZ, GİZEM; Cuzdan, Nihan; Gezer, Ilknur Albayrak; Keskin, Dilekk; Mulkoglu, Cevriye; Resorlu, Hatice; Ataman, Sebnem; Bal, Ajda; Duruoz, Mehmet Tuncay; Kucukakkas, Okan; YURDAKUL, Ozan Volkan; Melikoglu, Meltem Alkan; Aydin, Yildiray; Ayhan, F. Figen; Bodur, Hatice; Calis, Mustafa; Capkin, Erhan; Devrimsel, Gul; Gok, Kevser; Hizmetli, Sami; Kamanli, Ayhan; Ecesoy, Hilal; Kutluk, Oznur; Sen, Nesrin; Sendur, Omer Faruk; Tekeoglu, Ibrahim; Tolu, Sena; Toprak, Murat; Tuncer, Tiraje; KESKİN, YAŞAR; KÜÇÜKAKKAŞ, OKAN; YURDAKUL, OZAN VOLKANObjectives: This study aims to evaluate the coexistence of metabolic syndrome (MetS) and fibromyalgia syndrome (FMS) and determine the effects of this coexistence on neuroendocrine levels and clinical features of FMS.