Person: ÇAĞMAN, ZEYNEP
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Publication A Candidate Therapeutic Target For Diabetic Nephropathy: Gas6 (Growth Arrest Spesific Protein)(2010-06-12T00:00:00Z) Çağman, Zeynep; ÇAĞMAN, ZEYNEPPublication Reference Interval For Plasma Gas6 Growth Arrest Specific 6(2012-07-18T00:00:00Z) Çağman, Zeynep; ÇAĞMAN, ZEYNEPPublication THE RELATION BETWEEN GROWTH ARREST-SPECIFIC 6 (GAS6) AND CONVENTIONAL CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH PSORIASIS(2014-05-01T00:00:00Z) Uras, F.; SÜNBÜL, MURAT; Cagman, Zeynep; Gerin, F.; ÖZGEN, ZÜLEYHA; Durmus, E.; Seckin, D.; Agirbasli, M.; ÇAĞMAN, ZEYNEPPublication SERUM GROWTH ARREST PROTEIN 6 LEVELS BEFORE AND AFTER VITAMIN K PROPHYLAXIS IN TERM AND PRETERM NEWBORNS(2014-05-01T00:00:00Z) Alp, E. Eksi; Cagman, Zeynep; Uras, F.; Ercan, R. Gokmen; Altinkaya, N.; ÇAĞMAN, ZEYNEPPublication Estimation Of Reference İntervals For Plasma Growth Arrest-Specific 6(2017-04-29T00:00:00Z) Çağman, Zeynep; ÇAĞMAN, ZEYNEPPublication Sağlıklı yetişkinlerde plazma Gas6 seviyelerinin belirlenmesi(2010-09-25T00:00:00Z) Çağman, Zeynep; ÇAĞMAN, ZEYNEPPublication Mesane Kanserli Hastalarda Gas6 Gen Ekspresyonu Ve Tirozin Kinaz Axl – Sky Reseptorleri: Tumor Evresi Ve Derecesi İle İlişkisi(2013-11-07T00:00:00Z) Çağman, Zeynep; ÇAĞMAN, ZEYNEPPublication Alendronatın Overektomili Sıçanlarda Karaciğer Dokusu Üzerindeki Biyokimyasal Etkileri(2011-07-02T00:00:00Z) Çağman, Zeynep; ÇAĞMAN, ZEYNEPPublication Association of plasma growth arrest-specific protein 6 (Gas6) concentrations with albuminuria in patients with type 2 diabetes(2014-06-01T00:00:00Z) Erek-Toprak, Aybala; Bingol-Ozakpinar, Ozlem; Karaca, Zeynep; Cikrikcioglu, Mehmet Ali; Hursitoglu, Mehmet; Uras, Ahmet Riza; Adeli, Khosrow; Uras, Fikriye; ÇAĞMAN, ZEYNEPAims: New biomarkers are required to detect diabetic nephropathy earlier in persons with type 2 diabetes mellitus. Recent experimental studies indicate that growth arrest-specific protein 6 (Gas6) may have a role in pathogenesis of complications associated with diabetes. The objective of the current study is to examine whether plasma Gas6 concentrations are associated with albuminuria in persons with type 2 diabetes mellitus. Methods: About 32 patients with diabetes which have micro or macroalbuminuria, 37 patients with diabetes and normoalbuminuria, and 30 healthy volunteers were recruited. Plasma Gas6 levels were measured by ELISA. Hemoglobin A(1c) (HbA(1c)), serum C reactive protein, fibrinogen and 24-h urine samples for microalbuminuria were analyzed by Primus PDQ, Beckman Coulter Immage 800, STA Compact and Roche Cobas Integra 800 analyzer, respectively. Statistical analysis was performed using SPSS (Statistical Package for Social Sciences) for Windows 11.5. Results: There was a noteworthy difference among the three groups for Gas6 according to the Kruskal-Wallis test (p<0.01). Plasma Gas6 concentrations were higher in patients with micro or macroalbuminuria [20.9 ng/mL (16.7-27.0); median (25-75% percentile)] compared to patients with normoalbuminuria [16.5 ng/mL (13.1-22.9)], and healthy controls [15.3 ng/mL (8.3-33.6)]. Conclusions: In conclusion, this is the first study indicating that plasma Gas6 levels are associated with albuminuria in patients with type 2 diabetes. This study could be considered a starting point to focus on the association between Gas6 and diabetic nephropathy.Publication Gas6 gene expression and tyrosine kinase Axl Sky receptors: Its relation with tumor stage and grade in patients with bladder cancer(2014-04-15T00:00:00Z) Çağman, Zeynep; ÇAĞMAN, ZEYNEP
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