Person: ZORLU, MEHMET
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Publication Metadata only Sensitization pattern of inhalant allergens in children with asthma who are living different altitudes in Turkey(2015-11-01T00:00:00Z) ÖZKAYA, EMİN; Sogut, Ayhan; Kucukkoc, Mehmet; Eres, Mustafa; Acemoglu, Hamit; YÜKSEL, HASAN; MURAT, NACİ; ÖZKAYA, EMİN; ZORLU, MEHMETVariability in children-s allergic sensitization has been detected not only among different countries but also among cities within the same nation but yet different climatic areas. The aim of this study was to investigate the sensitization pattern of asthmatic children who lived in different altitude areas: the two largest Turkish cities, Istanbul (sea level) and Erzurum (high altitude). Five hundred and twelve asthmatic children (6-15 years old) from Istanbul (western Turkey, at sea level) and 609 from Erzurum (eastern Turkey, at an altitude of 1800 m) were included in the study. All participants underwent skin testing with common inhalant allergens, spirometry, total IgE level, and clinical examination. The positive sensitization ratio to aeroallergens in children with asthma living at sea level was statistically higher than that in children living in the high altitude group [p = 0.001, OR (odds ratio) 4.9 (confidence interval (CI) 3.67-6.459)]. However, pollen sensitization in asthmatic children living in high altitudes was significantly higher than that in children living at sea level [p = 0.00, OR 2.6 (CI 1.79-3.87)]. Children with asthma who live at high altitudes are characterized by higher pollen but lower mite sensitization rates than those living at sea level in Turkey. Different climatic conditions and altitudes may affect aeroallergen sensitization in children with asthma.Publication Metadata only Evaluation of the relationship between vitamin D level and adropin, IL-1β, IL-6, and oxidative status in women(2022-01-01T00:00:00Z) ZORLU, MEHMET; ŞEKERCİ, ABDÜSSELAM; TUNÇ, MUHAMMED; Güler, Eray Metin; Gülen, Bedia; KARATOPRAK, CUMALİ; KISKAÇ, MUHARREM; ÇAKIRCA, MUSTAFA; ZORLU, MEHMET; ŞEKERCİ, ABDÜSSELAM; TUNÇ, MUHAMMED; KARATOPRAK, CUMALİ; KISKAÇ, MUHARREM; ÇAKIRCA, MUSTAFABackground: Vitamin D, adropin, proinflammatory cytokines, and oxidative stress closely related with metabolic homeostasis and endothelial dysfunction. The aim of the present study is to investigate how vitamin D levels affect serum adropin, IL-1ß, IL-6, and oxidative stress. Methods: A total of 77 female subjects were divided into 3 groups according to vitamin D levels. Biochemical parameters, adropin, IL-1ß, IL-6, oxidative stress markers were studied in these groups, and the results were compared statistically. Results: Serum adropin, IL-1ß, IL-6, total oxidant status (TOS) and total antioxidant status (TAS) and oxidative stress index (OSI) levels differed significantly between the vitamin D groups (p < 0.05). A significant positive correlation was detected between vitamin D, and adropin and TAS (r = 0.807; p < 0.001, r = 0.814; p < 0.001, respectively). A significant negative correlation was detected between vitamin D, and IL-1ß, IL-6, TOS, OSI (r = -0.725; p < 0.001, r = -0.720; p < 0.001, r = -0.238; p = 0.037, r = -0.705; p < 0.001, respectively). Discussion: Vitamin D could show its effects through vitamin D receptors on tissues or on the ENHO gene in adropin secreting tissues via direct or indirect mechanisms. Proinflammatory cytokines, oxidative stress, and adropin targeted studies could contribute to the prevention and treatment of diseases associated with vitamin D deficiency in future.Publication Metadata only Diyabetik hastalarda diyetisyen kontrolü sıklığı bunun hasta memnuniyeti ve kan şeker regülasyonu üzerine etkisi(2011-05-15) KISKAÇ, MUHARREM; ÇAKIRCA, MUSTAFA; YOLBAŞ, SERVET; ÇIKRIKÇIOĞLU, MEHMET ALİ; ZORLU, MEHMET; BÜYÜKAYDIN, BANU; KISKAÇ, MUHARREM; ÇAKIRCA, MUSTAFA; ZORLU, MEHMET; BÜYÜKAYDIN, BANUPublication Metadata only Diyabetik hastaların kullandıkları ilaçları bilmelerinin HbA1c üzerine etkisi var mı(2011-05-15) ÇAKIRCA, MUSTAFA; KISKAÇ, MUHARREM; YOLBAŞ, SERVET; ZORLU, MEHMET; PERU, CELALETTİN; ÇIKRIKÇIOĞLU, MEHMET ALİ; ÇAKIRCA, MUSTAFA; KISKAÇ, MUHARREM; ZORLU, MEHMETPublication Metadata only Diyabetik Nefropatili Hastalarda Oksidatif Stresin Rolü(2016-03-21T00:00:00Z) Terzioğlu, Cemal; GÜLER, ERAY METİN; Uçak, Sinem; Çakmak, Orhan; ZORLU, MEHMET; KISKAÇ, MUHARREM; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİN; ZORLU, MEHMET; KISKAÇ, MUHARREM; KOÇYİĞİT, ABDÜRRAHİMPublication Metadata only Diyabetik hastalardaki sigara kullanımı ve kan şekeri regülasyonu ile ilişkisi(2011-05-15) ZORLU, MEHMET; KISKAÇ, MUHARREM; YOLBAŞ, SERVET; ÇAKIRCA, MUSTAFA; BÜYÜKAYDIN, BANU; ZORLU, MEHMET; KISKAÇ, MUHARREM; ÇAKIRCA, MUSTAFA; BÜYÜKAYDIN, BANUPublication Metadata only A case of rhabdomyolysis complicated with acute renal failure after resumption of fenofibrate therapy: a first report.(2013-05-01) KıSKAÇ, MUHARREM; ZORLU, MEHMET; CAKIRCA, MUSTAFA; Karatoprak, CUMALİ; PERU, C; ERKOÇ, R; YAVUZ, E; KISKAÇ, MUHARREM; ZORLU, MEHMET; ÇAKIRCA, MUSTAFA; KARATOPRAK, CUMALİPublication Metadata only RENAL TUBULAR FUNCTION IN CHILDREN W?TH NON CYSTIC FIBROSIS BRONCHIECTASIS(2015-05-01T00:00:00Z) Kucukkoc, Mehmet; Gedik, Ahmet Hakan; ÇAKIR, Erkan; Goknar, Nilufer; Demir, Aysegul Dogan; Yuksel, Mine; GÜZEL, GÜLSÜM; ZORLU, MEHMET; ÇAKIR, ERKAN; GÜZEL, GÜLSÜMPublication Metadata only Tekrarlayan piyüri ile gelen ve ailevi akdeniz ateşi tanısı konulan olgu sunumu(2014-10-19) KARATOPRAK, CUMALİ; ERKOÇ, REHA; ÇIKRIKÇIOĞLU, MEHMET ALİ; KISKAÇ, MUHARREM; ZORLU, MEHMET; ÇAKIRCA, MUSTAFA; ÇETİN, GÜVEN; KAZANCIOĞLU, RUMEYZA; KARATOPRAK, CUMALİ; KISKAÇ, MUHARREM; ZORLU, MEHMET; ÇAKIRCA, MUSTAFA; ÇETİN, GÜVENPublication Metadata only Pott-s disease and hypercalcemia in a patient with rheumatoid arthritis receiving methotrexate monotherapy(2013-11-01) KARATOPRAK, CUMALİ; ZORLU, MEHMET; KıSKAÇ, MUHARREM; CAKIRCA, MUSTAFA; YAVUZ, E; Cetin, GÜVEN; CIKRIKCIOGLU, MA; ZORLU, MEHMET; KISKAÇ, MUHARREM; KARATOPRAK, CUMALİ; ÇAKIRCA, MUSTAFA; ÇETİN, GÜVEN