Person: GÖKMEN KARASU, AYŞE FİLİZ
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Publication Metadata only Administration of rectal cytotec versus rectal buscopan before hysteroscopy(2020-06-01T00:00:00Z) GÖKMEN KARASU, AYŞE FİLİZ; AYDIN, SERDAR; ATEŞ, SEDA; TAKMAZ, TAHA; Comba, Cihan; GÖKMEN KARASU, AYŞE FİLİZ; AYDIN, SERDAR; ATEŞ, SEDA; TAKMAZ, TAHAIntroduction:Our objective was to compare the effect of rectal misoprostol (Cytotec) versus rectal hyoscine-n-butyl bromide (Buscopan) on patients undergoing hysteroscopy. We hypothesised that HBB may have a role in cervical priming. Material and methods:This trial was conducted at Bezmialem Vakif University Hospital. Women of reproductive age between 18-50 years who were scheduled for operative hysteroscopy indicated by type 1 submucous myoma or endometrial polyps were recruited for the study. Ninety patients were divided randomly into three groups. Group 1 received placebo treatment. Group 2 received rectal 200 mcg misoprostol and Group 3 received rectal 20 mg hyoscine-n-butyl bromide two hours before the procedure. Procedures were performed using a bipolar 26 F (9 mm) continuous-flow rigid resectoscope with a 30 degrees lens. The outcome measures included cervical dilation width and time, ease of cervical dilation, procedure time and operative complications. Postoperative self-rated pain was assessed one hour after the procedure. Results:Thirteen patients (43. 3%) in the placebo treatment group, 11 patients (36.7%) in the misoprostol group and four patients (13.3%) in the hyoscine-n-butyl bromide group needed analgesics postoperatively (p = .02). The mean duration of cervical dilation time was longest in Group 1 and shortest in Group 3, however this difference did not reach statistical significance (p=.11). There was no difference with regard to other studied parameters. Summary:HBB reduced the need for pain medication compared to placebo. Larger studies are needed to further investigate the role of HBB in facilitating pre-operative cervical priming.Publication Metadata only Is procidentia a distinct disease Comparison of risk factors(2016-05-21T00:00:00Z) AYDIN, SERDAR; KILIÇ, GÖKHAN; DANSUK, RAMAZAN; GÖKMEN KARASU, AYŞE FİLİZ; AYDIN, SERDAR; KILIC, GÖKHAN; DANSUK, RAMAZAN; GÖKMEN KARASU, AYŞE FİLİZPublication Metadata only A rat hysteropexy model for evaluating adhesion formation and comparison of two different structured meshes.(2017-11-01T00:00:00Z) Gokmen-Karasu, Ayse Filiz; Aydin, SERDAR; Sonmez, Fatma Cavide; Adanir, Ilknur; Ilhan, Gulsah; Ates, Seda; GÖKMEN KARASU, AYŞE FİLİZ; AYDIN, SERDAR; ATEŞ, SEDAIntroduction and hypothesis Peritonization of mesh during sacrohysteropexy is generally advocated to prevent adhesions to the viscera; however, randomized clinical trials are lacking, and peritonization may not be completely possible in a laparoscopic hysteropexy procedure. Our main objective was to describe a basic experimental rat sacrohysteropexy model. We hypothesized that even when peritoneal closure was omitted, using composite mesh would result in less adhesions to the viscera.Publication Metadata only Association between maternal vitamin D status in pregnant women and risk of gestational diabetes mellitus(2016-05-15T00:00:00Z) ATEŞ, SEDA; AYDIN, SERDAR; GÖKMEN KARASU, AYŞE FİLİZ; KILIÇ, GÖKHAN; KILIÇOĞLU DANE, PAKİZER BANU; ATEŞ, SEDA; AYDIN, SERDAR; GÖKMEN KARASU, AYŞE FİLİZ; KILIC, GÖKHAN; KILIÇOĞLU DANE, PAKİZER BANUPublication Metadata only Search for the G spot: microvessel and nerve mapping of the paraurethral anterior vaginal wall(2020-06-01T00:00:00Z) AYDIN, SERDAR; SÖNMEZ, FATMA CAVİDE; GÖKMEN KARASU, AYŞE FİLİZ; GÜL, Burcu; Arioglu, Cagri; AYDIN, SERDAR; SÖNMEZ, FATMA CAVİDE; GÖKMEN KARASU, AYŞE FİLİZ; GÜL, BURCUIntroduction and hypothesis Orgasm and other sexual responses such as pain, arousal and lubrication may be mediated by nerve fibers and vessels in the lamina propria and muscularis of the vaginal wall, in which case the number of nerve fibers and vessels would be associated with sexual functions. The aim of the study is to map the distribution of nerves and vessels in the anterior vaginal wall along the paraurethral region in a systematic fashion. Methods Specimens were taken from women with anterior vaginal wall prolapse undergoing colporrhaphy anterior repair. All specimens were mapped in a standard way starting 15 mm proximal to the external urethral orifice. Selected blocks of samples were immunohistochemically stained: actin, smooth muscle Ab-1 and S100 Protein Ab-1. The numbers of microvessels and nerves in the lamina propria and muscularis were counted in five consecutive high-power fields of a light microscope. Pairwise comparisons of proximal, distal, right and left paravaginal microvessel and nerve fiber density were analyzed with paired-sample t-test or Wilcoxon signed-rank test. Results Vaginal nerve fibers in the lamina propria and muscularis have a fairly even distribution in the anterior vaginal wall. Vaginal small vessel vascularization and microvascularization are also evenly distributed, with no concentrated site along the paraurethral region of the anterior vaginal wall. Conclusions Nerve fiber, nerve bundle, microvessel and small vessel densities in the lamina propria and muscularis were fairly regular, with no concentrated site on the paraurethral region of the anterior vaginal wall.Publication Metadata only Dental health dispositions of pregnant women: A survey from a hospital clinic in Istanbul.(2017-08-01) Gokmen, Karasu; KUTUK, NÜKHET; Aydin, SERDAR; Adanir, I; Ates, SEDA; Bademler, N; GÖKMEN KARASU, AYŞE FİLİZ; KÜTÜK, NÜKHET; AYDIN, SERDAR; ADANIR, İLKNUR; ATEŞ, SEDAPublication Metadata only Association between maternal vitamin D status and risk of gestational diabetes mellitus in pregnant women(2017-03-01) ATEŞ, SEDA; AYDIN, SERDAR; GÖKMEN KARASU, AYŞE FİLİZ; KILIÇOĞLU DANE, PAKİZER BANU; ATEŞ, SEDA; AYDIN, SERDAR; GÖKMEN KARASU, AYŞE FİLİZ; KILIÇOĞLU DANE, PAKİZER BANUPublication Metadata only The usual suspect: cross-sectional study of fundal pressure at second stage of delivery and the association with pelvic floor damage(2020-09-01T00:00:00Z) TAKMAZ, TAHA; AYDIN, SERDAR; Gorchiyeva, Irana; GÖKMEN KARASU, AYŞE FİLİZ; TAKMAZ, TAHA; AYDIN, SERDAR; GÖKMEN KARASU, AYŞE FİLİZIntroduction and hypothesis Uterine fundal pressure is applied to accelerate birth by increasing the expulsive force of the uterus in the second stage of delivery. The aim of the study was to evaluate the effect of using uterine fundal pressure during the second stage of delivery on the rate of pelvic floor damage among primiparous women using three-dimensional transperineal ultrasonography. Methods The women were divided into two groups: the fundal pressure group included women where the fundal pressure maneuver was applied (n = 39); the control group included women who delivered spontaneously without fundal pressure (n = 47). 3D-TPU was performed within 48 h of delivery, and LAM biometry, LAM defect and loss of tenting were determined. Results Anteroposterior hiatal dimensions on resting, maximal Valsalva and maximal PFMC were found to be higher in the fundal pressure group (p < 0.0001,p = 0.008,p = 0.007, respectively). The mean hiatal area at rest was larger in the fundal pressure group than in the control group (p = 0.04). The rate of LAM defect was significantly higher in the fundal pressure group (p = 0.001). The rate of loss of tenting was significantly higher in the fundal pressure group (p < 0.0001). According to multivariate regression models, the fundal pressure was the only independent factor associated with LAM defect (OR = 5.63; 95% CI = 12.01-15.74) and loss of tenting (OR = 8.74; 95% CI = 2.89-26.43). Conclusions Fundal pressure during the second stage of delivery is associated with a higher risk of LAM defect and loss of anterior vaginal wall support.Publication Metadata only Is Procidentia a Distinct Disease? Comparison of Risk Factors(2016-07-01) AYDIN, SERDAR; GÖKMEN KARASU, AYŞE FİLİZ; AYDIN, SERDAR; GÖKMEN KARASU, AYŞE FİLİZPublication Metadata only Age is the only variable affecting microhematuria prevalance in pelvic organ prolapse(2017-10-21T00:00:00Z) GÖKMEN KARASU, AYŞE FİLİZ; AYDIN, SERDAR; ADANIR, İLKNUR; İLHAN, GÜLŞAH; MARAŞLI, MUSTAFA; ATEŞ, SEDA; GÖKMEN KARASU, AYŞE FİLİZ; AYDIN, SERDAR; ATEŞ, SEDA