2020-02-25T00:00:00Z, Türk, HM, Gültekin, MEHMET ALİ, Uysal, Ö, Beşiroğlu, M, Yilmaz, TF, Yurtsever, I, GÜLTEKİN, MEHMET ALİ, TÜRK, HACI MEHMET, TOPRAK, HÜSEYİN, YURTSEVER, İSMAİL, YILMAZ, TEMEL FATİH, SHARIFOV, RASUL, UYSAL, ÖMER

Purpose: We aimed to investigate whether there are any differences in apparent diffusion coefficient (ADC) values obtained from colorectal liver metastases (CRLM) according to Kirsten rat sarcoma (KRAS) gene mutation status.

2022-10-01, Ersöz C., İlktaç A., Kalkan S., Kayalı Y., Akbulut H., Toprak H., Doğan B., ERSÖZ, CEVPER, İLKTAÇ, ABDULLAH, KALKAN, SENAD, AKBULUT, HABİB, TOPRAK, HÜSEYİN, DOĞAN, BAYRAM

2022-03-24T00:00:00Z, Cetinkaya, Ezra, Aralasmak, Ayse, Atasoy, Bahar, Tokdemir, Sevil, Toprak, Huseyin, Toprak, Ali, Kurtcan, Serpil, Alkan, ALPAY, TOPRAK, HÜSEYİN, ALKAN, ALPAY

2023-02-01, Kayalı Y., Balbay M. D., İlktaç A., Ersöz C., Toprak H., Tarım K., Baygül A., Akçay M., Doğan B., İLKTAÇ, ABDULLAH, ERSÖZ, CEVPER, TOPRAK, HÜSEYİN, AKÇAY, MUZAFFER, DOĞAN, BAYRAM

2022-01-01T00:00:00Z, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA

Aim: We aimed to investigate the magnetic resonance imaging (MRI) features of benign, atypical, or malignant papillary breast lesions and to assess the additional value of diffusion-weighted imaging (DWI) and turbo inversion recovery magnitude (TIRM) sequences to routine breast MRI. Background: Differentiation between benign and malignant papillary breast lesions is essential for patient management. However, morphologic features and enhancement patterns of malignant papillary lesions may overlap with those of benign papilloma. Methods: Seventy-two papillary breast lesions (50 benign, 22 atypical or malignant) were included in the current study, retrospectively. We divided the patients into two groups: benign papillary breast lesions and atypical or malignant papillary breast lesions. Morphologic, dynamic, turbo inversion recovery magnitude (TIRM) values and diffusion features of the papillary lesions were compared between two groups. Results: Benign papillary lesions were smaller in size (p=0.006 and p=0.005, for radiologists 1 and 2 respectively), closer to the areola (p=0.045 and 0.049 for radiologist 1 and 2 respectively), and had higher ADC values (p=0.001 for two radiologists) than the atypical or malignant group. ROC curves showed diagnostic accuracy for ADC (AUC=0.770 and 0.762, p & lt; 0.0001 for two radiologists), and showed a cut-off value of <= 957 x 10-6 mm(2/s) (radiologist 1) and <= 910 x 10-6 mm(2/s) (radiologist 2). Conclusion: MRI is a useful method for differentiation between benign and malignant papillary breast lesions. Centrally located, lesser in size, and higher ADC values should be considered benign, whereas peripherally located, larger in size, and lower ADC values should be considered malignant.

2020-05-13T04:00:00Z, KILINÇ, YAĞMUR BAŞAK, SARI, LÜTFULLAH, KARABULUT, ÜMMÜHAN EBRU, AYKAN, MAHMUT ESAT, TOPRAK, HÜSEYİN, KILINÇ, YAĞMUR BAŞAK, SARI, LÜTFULLAH, KARABULUT, ÜMMÜHAN EBRU, AYKAN, MAHMUT ESAT, TOPRAK, HÜSEYİN

Intussusception usually occurs in children due to benign causes, whereas in adults, it is mostly caused by malign causes in the colon. On the other hand, the causes of small bowel intussusceptions in adulthood are usually benign, such as polyps, lipomas, adenomas, and Meckel-s diverticulum. Intestinal lipomas are an uncommon entity among benign tumors. Here, we present MR enterography features of jejunojejunal intussusception caused by an intramural lipoma.

2022-02-11, Çetinkaya E., Aralaşmak A., Goksungur G., Kaya M. O., Toprak H., Kolukısa M., Asıl T., Kurtcan S., Özdemir H., TOPRAK, HÜSEYİN

2022-01-01T00:00:00Z, YILMAZ, TEMEL FATİH, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, GÜCİN, ZÜHAL, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA, YILMAZ, TEMEL FATİH, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, GÜCİN, ZÜHAL, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA

To evaluate breast MRI and DWI and demographic features of pleomorphic invasive lobular carcinoma (pILC) and classic invasive lobular carcinoma (cILC). Invasive lobular (ILC) is the second most common breast malignancy after invasive ductal carcinoma (IDC) and constitutes the 8-14% of all invasive breast cancers. ILC morphologically can be classified into the classic, alveolar, solid, tubulolobular, and pleomorphic subtypes according to WHO. This study was performed retrospectively. The MRI and demographic features of 18 patients with 23 pILC were compared with those 22 consecutive patients with 27 cILC. There was no significant difference in demographic features of patients, MR appearance, kinetics, and ADC values between two groups. pILC, an aggressive subtype of ILC, cannot be differentiated from cILC with breast MRI.

2021-12-22T00:00:00Z, Yilmaz, TEMEL FATİH, Gultekin, Mehmet Ali, Turk, Hacı Mehmet, Cesme, Dilek Hacer, Besiroglu, Mehmet, Simsek, Melih, Toprak, Huseyin, Alkan, ALPAY, YILMAZ, TEMEL FATİH, TÜRK, HACI MEHMET, ÇEŞME, DİLEK HACER, ŞİMŞEK, MELİH, ALKAN, ALPAY, TOPRAK, HÜSEYİN

Background: We aimed to investigate whether there is a difference between intrahepatic cholangiocarcinoma (IHCC) and liver metastases of gastrointestinal system (GIS) adenocarcinoma in terms of apparent diffusion coefficient (ADC) values. Patients and methods: From January 2018 to January 2020, we retrospectively examined 64 consecutive patients with liver metastases due to gastrointestinal system adenocarcinomas and 13 consecutive IHCC in our hospital's medical records. After exclusions, fifty-three patients with 53 liver metastases and 10 IHCC were included in our study. We divided the patients into two groups as IHCC and liver metastases of GIS adenocarcinoma. For mean apparent diffusion coefficient (ADCmean) values, the region of interests (ROI) was placed in solid portions of the lesions. ADCmean values of groups were compared. Results: The mean age of IHCC group was 62.50 ± 13.49 and mean age of metastases group was 61.15 ± 9.18. ADCmean values were significantly higher in the IHCC group compared to the metastatic group (p < 0.001). ROC curves method showed high diagnostic accuracy (AUC = 0.879) with cut-off value of < 1178 x 10-6 mm2/s for ADCmean (Sensitivity = 90.57, Specificity = 70.0, positive predictive value [PPV] = 94.1, negative predictive value [NPV] = 58.3) in differentiating adenocarcinoma metastases from IHCC. Conclusions: The present study results suggest that ADC values have a potential role for differentiation between IHCC and GIS adenocarcinoma liver metastases which may be valuable for patient management.

2022-08-01T00:00:00Z, DEĞER, KAMURAN CUMHUR, KÖKER, İBRAHİM HAKKI, Destek, Sabahattin, TOPRAK, HÜSEYİN, Yapalak, Yunus, GÖNÜLTAŞ, CEREN, ŞENTÜRK, HAKAN, DEĞER, KAMURAN CUMHUR, KÖKER, İBRAHİM HAKKI, TOPRAK, HÜSEYİN, GÖNÜLTAŞ, CEREN, ŞENTÜRK, HAKAN

BACKGROUND: Groove pancreatitis (GP) is a rare form of chronic pancreatitis that is less common and is now gaining awareness with multimodal imaging modalities. Our aim is to analyze the mid-long term outcomes of patients diagnosed with GP with different treatment approaches.