Person: TOPRAK, HÜSEYİN
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Publication Open Access Diagnostic performance of apparent diffusion coefficient values for the differentiation of intrahepatic cholangiocarcinoma from gastrointestinal adenocarcinoma liver metastases(2021-12-22T00:00:00Z) Yilmaz, TEMEL FATİH; Gultekin, Mehmet Ali; Turk, Hacı Mehmet; Cesme, Dilek Hacer; Besiroglu, Mehmet; Simsek, Melih; Toprak, Huseyin; Alkan, ALPAY; YILMAZ, TEMEL FATİH; TÜRK, HACI MEHMET; ÇEŞME, DİLEK HACER; ŞİMŞEK, MELİH; ALKAN, ALPAY; TOPRAK, HÜSEYİNBackground: We aimed to investigate whether there is a difference between intrahepatic cholangiocarcinoma (IHCC) and liver metastases of gastrointestinal system (GIS) adenocarcinoma in terms of apparent diffusion coefficient (ADC) values. Patients and methods: From January 2018 to January 2020, we retrospectively examined 64 consecutive patients with liver metastases due to gastrointestinal system adenocarcinomas and 13 consecutive IHCC in our hospital's medical records. After exclusions, fifty-three patients with 53 liver metastases and 10 IHCC were included in our study. We divided the patients into two groups as IHCC and liver metastases of GIS adenocarcinoma. For mean apparent diffusion coefficient (ADCmean) values, the region of interests (ROI) was placed in solid portions of the lesions. ADCmean values of groups were compared. Results: The mean age of IHCC group was 62.50 ± 13.49 and mean age of metastases group was 61.15 ± 9.18. ADCmean values were significantly higher in the IHCC group compared to the metastatic group (p < 0.001). ROC curves method showed high diagnostic accuracy (AUC = 0.879) with cut-off value of < 1178 x 10-6 mm2/s for ADCmean (Sensitivity = 90.57, Specificity = 70.0, positive predictive value [PPV] = 94.1, negative predictive value [NPV] = 58.3) in differentiating adenocarcinoma metastases from IHCC. Conclusions: The present study results suggest that ADC values have a potential role for differentiation between IHCC and GIS adenocarcinoma liver metastases which may be valuable for patient management.Publication Metadata only A Rare Complication of Umbilical Vein Catheterization: TPNoma: US, X-ray, and MRI Findings(2023-01-01) Sari L.; ORAN Z.; Ali Gültekin M.; Sharifov R.; TOPRAK H.; SARI, LÜTFULLAH; ORAN, ZEYNEP; SHARIFOV, RASUL; TOPRAK, HÜSEYİNBACKGROUND: Umbilical vein catheterization (UVC) is an early venous access route in newborns and is frequently used for delivering total parenteral nutrition (TPN) and medications. Vascular, hepatic parenchymal, and infectious complications of UVC can be seen rarely. OBJECTIVE: We present preterm neonates\" X-ray, US, and MRI findings with parenchymal TPN extravasation and portal vein thrombosis. Our case was the first case about MRI findings of TPNoma. CASE PRESENTATION: A 30 week female with a birth weight of 1340 g was born via Cesarean section. Due to the diagnosis of transient tachypnea of the newborn and prematurity, the infant was hospitalized in the neonatal intensive care unit. On the first day of hospitalization, UVC was inserted and TPN with 20% lipid content was started. After 10 days, UVC was removed and TPN treatment was continued with a piccline catheter. Abdominal US and portal venous Doppler examination was applied to the patient whose general condition deteriorated on the 12th day. US and Doppler revealed a lesion of 17x17x18mm in size with lobulated contour, hyperechoic heterogeneous internal structure, and no central or peripheral blood supply was observed in the left lobe of the liver. Moreover, a filling defect compatible with a thrombus was observed in the proximal part of the left portal vein. An abdominal MRI was performed to characterize this liver lesion. Axial T1 weighted and T2- weighted images showed a heterogeneous hyperintense lesion without contrast enhancement. Axial fat saturation T1-weighted and out of phase T1-weighted images showed a reduction in signal intensity. US and MRI examinations showed that the thrombosed umbilical vein ended superior to the lesion. In the differential diagnoses, fat-containing lesions such as lipoma-teratoma and fat-containing collection secondary to extravasation of TPN treatment via UVC were thought. CONCLUSION: In the differential diagnosis of liver localized lesions in newborns, UVC-related liver injury should be considered and the localization of the catheter tip should be checked. In case of the doubt based on US and X-ray findings, presence of fat on MRI could be diagnosed. Serious complications should be avoided with catheter revision or removal.Publication Open Access Secondary Involvement of the Penis by Non-Hodgkin Lymphoma(2021-07-01T00:00:00Z) Timocin Yigman, Gizem; PEKER, ABDUSSELİM ADİL; SHARIFOV, RASUL; TOPRAK, HÜSEYİN; PEKER, ABDUSSELİM ADİL; SHARIFOV, RASUL; TOPRAK, HÜSEYİNPrimary penile lymphoma is extremely rare and there are less than 30 reported cases worldwide. Frequently penile lymphoma is seen as a secondary involvement of the penis by lymphoma, most likely by Non-Hodgkin lymphoma (NHL). Here, we report a case with penile lymphoma caused by previously known NHL.Publication Open Access CT and MRI findings of sarcomatoid cholangiocarcinoma.(2012-10-16) Bilgin, MEHMET; Toprak, HÜSEYİN; BILGIN, SABRİYE ŞENNUR; KONDAKÇI, MUSTAFA; BALCI, CEM NUMAN; BİLGİN, MEHMET; TOPRAK, HÜSEYİNComputed tomography (CT) and magnetic resonance imaging (MRI) findings for a case of intrahepatic sarcomatoid cholangiocarcinoma is presented. A 48-year-old man with upper abdominal pain underwent contrast-enhanced CT and MRI. A 13 10 7 cm mass was seen in the left liver lobe, which had hypodense internal architecture on CT and mixed signal intensities on both T1- and T2-weighted images with an overwhelmingly hypointense signal on T1-weighted images and a hyperintense signal on T2-weighted images. The lesion had heterogeneous enhancement on both CT and MRI. A satellite nodule with the same imaging features was distinctive for the lesion.Publication Open Access Radiological Appearences of Benign Soft-tissue Tumors of the Hand and Wrist with Special Emphasis on NRI(2022-04-01T00:00:00Z) YILMAZ, TEMEL FATİH; TOPRAK, HÜSEYİN; Atasoy, Bahar; SÖNMEZ, FATMA CAVİDE; ARALAŞMAK, Ayşe; GÜRKAN, Volkan; YILMAZ, TEMEL FATİH; TOPRAK, HÜSEYİN; ATASOY, BAHAR; SÖNMEZ, FATMA CAVİDE; ARALAŞMAK, AYŞE; GÜRKAN, VOLKANTumoral and pseudotumoral lesions of the hand and wrist are commonly encountered in routine clinical practice. Although most of them arc benign, radiological differential diagnosis of these lesions is difficult, because of their nonspecific imaging findings, except ganglia, localized type of tenosynovial giant cell tumors and lipomas. Digital radiography, computed tomography, and ultrasound may be useful in identification of the lesions in the wrist and hand, but magnetic resonance imaging with superior contrast and spatial resolution is the most important imaging modality.Publication Metadata only Advanced cerebrospinal fluid flow MRI findings of aqueductal stenosis caused by web(2023-01-01) YILMAZ T. F.; Sari L.; TOPRAK H.; YILMAZ, TEMEL FATİH; TOPRAK, HÜSEYİNBackground: The aqueductal web (AW) is one of the causes of aqueductus stenosis (AS). Recent advances in Magnetic resonance (MR) imaging have enabled us to better reveal the cerebrospinal fluid (CSF) flow dynamics and aqueductal anatomy. Purpose: The aim of this study is to evaluate the CSF flow dynamics of patients with AW with phase contrast Magnetic resonance imaging (MRI) and compare them with the imaging findings. Materials and Methods: We evaluated 23 patients under 65-year-old age. On constructive interference in steady-state (T2 CISS) images, the width of prepontine cistern (PPC) and the width of Sylvian aqueduct (SA) were measured. Localization and number of webs were evaluated. The existence of flow at the aqueduct and the presence of spontaneous third ventriculostomy (STV) were evaluated on sagittal Sampling Perfection with Application optimized Contrast (SPACE) sequences. Results: Of the 23 patients included in the study, 11 were male and 12 were female. The mean age was 34.02 (0.5–64). A total of 31 AWs were detected in 23 patients. Six of 23 patients (26.1%) had STV and 17 of those not. Four of 23 patients (17.4%) had aqueductal flow on SPACE sequences. The PPC distance was significantly wider in patients with STV (median: 6.7–4.5, interquartile range (IQR): 1.35, p = 0.004). In the cases where artifact secondary to flow is observed in SPACE sequences in aqueduct, the Evan index (EI) was significantly lower (median: 0.2955–0.3900, IQR: 0.03–0.14, p < 0.001). Conclusion: In patients with a low EI, there may be flow in the SA even if there is a web. In patients with a wide PPC distance, it is necessary to consider the presence of STV and evaluate the presence of flow with the SPACE sequences.Publication Metadata only Diagnostic utility of Magnetic Resonance Imaging in discriminating immature teratoma: Insights from a case series(2024-01-01) AKÇAY A.; Dönmez Z.; PEKER A. A.; TOPRAK H.; GÜLTEKİN M. A.; AKÇAY, AHMET; PEKER, ABDUSSELİM ADİL; TOPRAK, HÜSEYİN; GÜLTEKİN, MEHMET ALİImmature teratomas (IT) are rare germ cell tumors with malignant behavior, distinct from the benign mature teratomas. Clinical differentiation poses challenges, demanding a comprehensive, multidisciplinary diagnostic approach. This case series delves into the detailed radiological imaging findings of ITs. Pelvic MRI was conducted on five cases with adnexal masses, all of which were histopathologically confirmed as ITs. Radiologically, larger tumor size and scattered fatty components were key diagnostic indicators. This study underlines the importance of comprehensive evaluation in IT diagnosis and management, with MRI as an essential tool in the clinical workflow.