Person: TOPRAK, HÜSEYİN
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Publication Open Access Diagnostic value of dynamic contrast-enhanced magnetic resonance imaging in the evaluation of the biliary obstruction(2012-01-01) BALCI, CEM NUMAN; Bilgin, MEHMET; Toprak, HÜSEYİN; BURGAZLI, MEHMET; BILGIN, SABRİYE ŞENNUR; CHASAN, RITVAN; ERDOĞAN, ALİ; BİLGİN, MEHMET; TOPRAK, HÜSEYİNPurpose: In this study, our purpose was to investigate the diagnostic efficacy of the dynamic contrast-enhanced magnetic resonance imaging (MRI) method in the patients with bile duct obstruction. Materials and methods: 108 consecutive patients (53 men, 55 women, mean age; 55.77 ± 14.62, range 18-86 years) were included in this study. All the patients underwent conventional upper abdomen MRI using intravenous contrast material (Gd-DTPA) and MRCP in 1.5 Tesla MRI scanner. MRCP images were evaluated together with the T1 and T2w images, and both biliary ducts and surrounding tissues were examined for possible pathologies that may cause obstruction. Results: MRI/MRCP findings compared with final diagnoses, MRI/MRCP in the demonstration of bile duct obstruction sensitivity 96%, the specificity 100%, and accuracy 96.3%, in the detection of presence and level of obstruction, the sensitivity 96.7%, specificity 100%, and accuracy 97.2%, in the diagnosis of choledocholithiasis, the sensitivity 82.3%, specificity 96%, and accuracy 91.7%, and in the determination of the character of the stenosis, sensitivity 95.6%, specificity 91.3%, and accuracy 94.5% were found. Conclusion: The combination of dynamic contrast-enhanced MRI and MRCP techniques in patients with suspected biliary obstruction gives the detailed information about the presence of obstruction, location, and causes and is a highly specific and sensitive method.Publication Open Access MRI and MR Spectroscopy Features of Heat Stroke: A Case Report(2018-07-01) Yilmaz, TEMEL FATİH; Aralasmak, AYŞE; Toprak, HÜSEYİN; GULER, Serhat; Tüzün, Umit; Alkan, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; ALKAN, ALPAYHeat stroke is the outcome of over heat stress that results in multiorgan dysfunction with a tendency for central nervous system damage. Brain is very sensitive to hyperthermia, especially the cerebellum that has selective vulnerability to heat stroke. There is complex interaction between heat cytotoxicity, coagulation disorder, cytotoxine - mediated systemic inflammatory response causing multiorgan failure, metabolic derangement, and circulatory insufficiency. We reviewed the literature and discussed brain MRI and MR spectroscopy findings of heat stroke, detailed the pathophysiology underlying brain involvement and proposed excitotoxic injury as an alternative mechanism of brain damage in heat stroke.Publication Open Access Stab injury of the thoracic aorta: computed tomography findings.(2013-01-01) Yildiz, S; Toprak, HÜSEYİN; SERTER, ASLI; KOCAKOÇ, ERCAN; YILDIZ, ŞEYMA; TOPRAK, HÜSEYİNStab injury of the thoracic aorta is a rare condition with high mortality rate. Patients must be evaluated carefully, and the diagnosis usually should be confirmed by radiological modalities. In this case, we report a 37-year-old man presented with a penetrating stab injury to the upper back and the thoracic aorta, and the diagnostic role of computed tomography is discussed.Publication Open Access Prenatal diagnosis of mediastinal neurenteric cyst: a case report and review of the literature(2018-10-01) Cay, ALİ; Aydogdu, Ibrahim; Mirapoglu, Semih Lutfu; Toprak, HÜSEYİN; ÇAY, ALI; AYDOĞDU, İBRAHİM; TOPRAK, HÜSEYİNNeurenteric cyst is a very rare developmental anomaly. Prenatal diagnosis of mediastinal neurenteric cysts has been reported rarely. We present a case of neurenteric cyst associated with vertebral anomalies diagnosed by prenatal ultrasonography at 31 weeks of gestation, which was treated successfully in the early neonatal period. In addition, we searched the English literature for all cases of mediastinal neurenteric cyst diagnosed in the prenatal period reported to date. We found that only 17 cases were reported previously. We reviewed the reports of these 17 patients along with our case, and we investigated the prenatal and postnatal diagnosis and treatment approaches and the factors influencing the prognosis. Fetuses with mediastinal neurenteric cysts should be monitored regularly by ultrasonography. Fetuses with no signs of hydrops are more likely to survive with proper neonatal center transfer, regular follow-up, and appropriate postnatal approach. Fetuses with hydrops findings have a high risk of fetal and neonatal death.Publication Open Access Ultrasound and Doppler US in Evaluation of Superficial Soft-tissue Lesions.(2014-02-27) Toprak, HÜSEYİN; KILIÇ, ERKAN; SERTER, ASLI; KOCAKOÇ, E; OZGOCMEN, SALİH; TOPRAK, HÜSEYİNImproved developments in digital ultrasound technology and the use of high‑frequency broadband transducers make ultrasound (US) imaging the first screening tool in investigating superficial tissue lesions. US is a safe (no ionizing radiation), portable, easily repeatable, and cheap form of imaging compared to other imaging modalities. US is an excellent imaging modality to determine the nature of a mass lesion (cystic or solid) and its anatomic relation to adjoining structures. Masses can be characterized in terms of their size, number, component, and vascularity with US and Doppler US especially with power Doppler US. US, however, is operator dependent and has a number of artifacts that can result in misinterpretation. In this review, we emphasize the role of ultrasound, particularly power Doppler, in superficial soft‑tissue lesions.Publication Open Access CT and MRI Findings of Hepatic Involvement in Rendu-Osler-Weber Disease.(2012-01-01) Bilgin, MEHMET; Yildiz, S; Toprak, HÜSEYİN; AHMAD, ISSAM CHEIKH; KOCAKOÇ, ERCAN; BİLGİN, MEHMET; YILDIZ, ŞEYMA; TOPRAK, HÜSEYİNRendu-Osler-Weber disease is a rare autosomal dominant disorder. Hepatic involvement manifests itself as vascular, parenchymal, and biliary lesions with characteristic telangiectasias and vascular shunts. In a 37-year-old female patient, dynamic contrastenhanced upper abdominal CT and MRI were performed. CT and MRI revealed dilated celiac trunk and hepatic artery. On early arterial phase, dilated hepatic veins showed significant enhancement. On arterial and portal venous phases, liver showed significantly heterogeneous contrast enhancement and showed homogenous enhancement in the hepatic parenchymal phase. On the magnetic resonance cholangiopancreatography, irregular biliary ducts with strictures and dilatation were seen.Publication Open Access Comparison of two types of proximal femoral hails in the treatment of intertrochanteric femur fractures(2015-09-01) Uzer, GÖKÇER; Elmadag, NUH MEHMET; Yildiz, FATİH; Bilsel, Kerem; Erden, TUNAY; Toprak, HÜSEYİN; UZER, GÖKÇER; ELMADAĞ, NUH MEHMET; YILDIZ, FATİH; BİLSEL, İSMAIL KEREM; ERDEN, TUNAY; TOPRAK, HÜSEYİNBackground: Hip nailing is frequently used to treat unstable intertrochanteric femoral fractures (ITF) in elderly patients. In this retrospective study, we compared the functional and radiological results, and the complications, of patients treated using proximal femoral nails (PFN) with an integrated, interlocking, compression lag screw, or two separate lag screws, which allow linear compression at the fracture site. Methods: A total of one hundred and eighteen patients were operated on for AO/OTA 31-A2 ITF between May 2010 and April 2012, and eighty-two of these patients, for whom sufficient follow-up data and documentation were available, were included into the study. PFNs with interlocking, integrated lag screws (Group I) were used in forty-four patients, and PFNs with two separate lag screws (Group II) in thirty-eight. Outcome parameters were the extent of varus collapse and leg length discrepancy on radiographs, and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) and Harris hip scores (HHS) as functional results. Results: Mean follow-up duration was 20 months (range, 12-36 months); fractures healed in all patients. Mean varus collapse values were 2.03±5.68° and 5.21±5.27° (p=0.01), Harris hip scores 73.2±11.65 and 74.72±11.15 (p=0.54), and WOMAC scores 70.78±11.41 and 71.78±11.19 (p=0.69) in Groups I and II, respectively. No difference was detected between the groups in terms of outcome parameters or complication rate. Conclusion: In the treatment of ITF, PFNs with an integrated, interlocking, compression lag screw, or two separate lag screws did not differ in terms of functional and radiological results or complication rate.Publication Open Access Coexistence of osteopoikilosis with seronegative spondyloarthritis and spinal stenosis.(2015-05-01) DEMIR, SALİHA EROĞLU; ÖZARAS, NİHAL; POYRAZ, ELİF; Toprak, HÜSEYİN; GÜLER, MUSTAFA; TOPRAK, HÜSEYİN[Purpose] Osteopoikilosis is a rare hereditary bone disease that is usually asymptomatic. It is generally diagnosed incidentally on plain radiography. The coexistence of osteopoikilosis with seronegative spondyloarthritis or spinal stenosis is rarely reported. Here, we report the case of a 27-year-old male patient with osteopoikilosis, seronegative spondyloarthritis, and spinal stenosis. [Subject] A 27-year-old male patient with buttock pain and back pain radiating to the legs. [Methods] A plain anteroposterior radiograph of the pelvis revealed numerous round and oval sclerotic bone areas of varying size. Investigation of the knee joints showed similar findings, and the patient was diagnosed with osteopoikilosis. Lumbar magnetic resonance images showed spinal stenosis and degenerative changes in his lumbar facet joints. Magnetic resonance images of the sacroiliac joints showed bilateral involvement with narrowing of both sacroiliac joints, nodular multiple sclerotic foci, and contrast enhancement in both joint spaces and periarticular areas. HLA B-27 test was negative. [Results] The patient was diagnosed with osteopoikilosis, seronegative spondyloarthritis, and spinal stenosis. Treatment included asemetasin twice daily and exercise therapy. [Conclusion] Symptomatic patients with osteopoikilosis should be investigated for other possible coexisting medical conditions; this will shorten the times to diagnosis and treatment.Publication Open Access Correlation between Breast Arterial Calcification and the 10-year fatal cardiovascular risk by means of the SCORE Risk System.(2018-11-01T00:00:00Z) Yildiz, S; Yildiz, A; Toprak, HÜSEYİN; Kocas, C; YILDIZ, ŞEYMA; TOPRAK, HÜSEYİNObjectives: The aim of this study was to investigate the relationship between Breast Arterial Calcification (BAC) on mammography and the 10-year fatal Cardiovascular Disease (CVD) risk by using SCORE risk system. Methods: The study was conducted from September 2013 to July 2014. A total of 66 women with BAC and 66 age-matched controls without BAC were analyzed. The groups were compared with respect to demographics, clinical, reproductive, laboratory parameters, and 10-year fatal CVD risk. Results: The mean ages of the women in the study was 54.0 years (40-85 years). Hypertension, systolic blood pressure, levels of serum total cholesterol and the calculated SCORE risk were higher in the BAC (+) group than in the BAC (-) group (p=0.04, p=0.031, p=0.046, and p=0.038 respectively). Multivariate analysis showed that none of them was independent factor of BAC on mammograms, only the 10-year fatal CVD risk was close to being statistically significant (OR:1.17, CI:0.98-1.38, p=0.06). Conclusion: BAC on mammography was found to be related to the 10-year fatal CVD risk as calculated by the SCORE risk score system. Additional large-scale prospective studies are required to further assess whether BAC can be considered a useful screening tool for CVD risk prediction in women who screened for breast cancer by mammography.Publication Open Access Interhemispheric Acute Subdural Hematoma: A Distinct Entity of Subdural Hematoma.(2016-02-01) SOGUT, OZGUR; YIGIT, MEHMET; TURKDOGAN, KENAN AHMET; YIGIT, EDa; Gulen, BEDİA; Sonmez, ERTAN; KAPLAN, ONUR; Toprak, HÜSEYİN; GÜLEN, BEDİA; SÖNMEZ, ERTAN; TOPRAK, HÜSEYİN