2020-02-25T00:00:00Z, Türk, HM, Gültekin, MEHMET ALİ, Uysal, Ö, Beşiroğlu, M, Yilmaz, TF, Yurtsever, I, GÜLTEKİN, MEHMET ALİ, TÜRK, HACI MEHMET, TOPRAK, HÜSEYİN, YURTSEVER, İSMAİL, YILMAZ, TEMEL FATİH, SHARIFOV, RASUL, UYSAL, ÖMER

Purpose: We aimed to investigate whether there are any differences in apparent diffusion coefficient (ADC) values obtained from colorectal liver metastases (CRLM) according to Kirsten rat sarcoma (KRAS) gene mutation status.

2022-01-01T00:00:00Z, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, YILMAZ, TEMEL FATİH, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA

Aim: We aimed to investigate the magnetic resonance imaging (MRI) features of benign, atypical, or malignant papillary breast lesions and to assess the additional value of diffusion-weighted imaging (DWI) and turbo inversion recovery magnitude (TIRM) sequences to routine breast MRI. Background: Differentiation between benign and malignant papillary breast lesions is essential for patient management. However, morphologic features and enhancement patterns of malignant papillary lesions may overlap with those of benign papilloma. Methods: Seventy-two papillary breast lesions (50 benign, 22 atypical or malignant) were included in the current study, retrospectively. We divided the patients into two groups: benign papillary breast lesions and atypical or malignant papillary breast lesions. Morphologic, dynamic, turbo inversion recovery magnitude (TIRM) values and diffusion features of the papillary lesions were compared between two groups. Results: Benign papillary lesions were smaller in size (p=0.006 and p=0.005, for radiologists 1 and 2 respectively), closer to the areola (p=0.045 and 0.049 for radiologist 1 and 2 respectively), and had higher ADC values (p=0.001 for two radiologists) than the atypical or malignant group. ROC curves showed diagnostic accuracy for ADC (AUC=0.770 and 0.762, p & lt; 0.0001 for two radiologists), and showed a cut-off value of <= 957 x 10-6 mm(2/s) (radiologist 1) and <= 910 x 10-6 mm(2/s) (radiologist 2). Conclusion: MRI is a useful method for differentiation between benign and malignant papillary breast lesions. Centrally located, lesser in size, and higher ADC values should be considered benign, whereas peripherally located, larger in size, and lower ADC values should be considered malignant.

2022-01-01T00:00:00Z, YILMAZ, TEMEL FATİH, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, GÜCİN, ZÜHAL, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA, YILMAZ, TEMEL FATİH, OTÇU TEMUR, HAFİZE, SARI, LÜTFULLAH, GÜCİN, ZÜHAL, GÜLTEKİN, MEHMET ALİ, ÇELİK YABUL, FATMA, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA

To evaluate breast MRI and DWI and demographic features of pleomorphic invasive lobular carcinoma (pILC) and classic invasive lobular carcinoma (cILC). Invasive lobular (ILC) is the second most common breast malignancy after invasive ductal carcinoma (IDC) and constitutes the 8-14% of all invasive breast cancers. ILC morphologically can be classified into the classic, alveolar, solid, tubulolobular, and pleomorphic subtypes according to WHO. This study was performed retrospectively. The MRI and demographic features of 18 patients with 23 pILC were compared with those 22 consecutive patients with 27 cILC. There was no significant difference in demographic features of patients, MR appearance, kinetics, and ADC values between two groups. pILC, an aggressive subtype of ILC, cannot be differentiated from cILC with breast MRI.