2018-07-01, Yilmaz, TEMEL FATİH, Aralasmak, AYŞE, Toprak, HÜSEYİN, GULER, Serhat, Tüzün, Umit, Alkan, ALPAY, YILMAZ, TEMEL FATİH, ARALAŞMAK, AYŞE, TOPRAK, HÜSEYİN, ALKAN, ALPAY

Heat stroke is the outcome of over heat stress that results in multiorgan dysfunction with a tendency for central nervous system damage. Brain is very sensitive to hyperthermia, especially the cerebellum that has selective vulnerability to heat stroke. There is complex interaction between heat cytotoxicity, coagulation disorder, cytotoxine - mediated systemic inflammatory response causing multiorgan failure, metabolic derangement, and circulatory insufficiency. We reviewed the literature and discussed brain MRI and MR spectroscopy findings of heat stroke, detailed the pathophysiology underlying brain involvement and proposed excitotoxic injury as an alternative mechanism of brain damage in heat stroke.

2021-12-22T00:00:00Z, Yilmaz, TEMEL FATİH, Gultekin, Mehmet Ali, Turk, Hacı Mehmet, Cesme, Dilek Hacer, Besiroglu, Mehmet, Simsek, Melih, Toprak, Huseyin, Alkan, ALPAY, YILMAZ, TEMEL FATİH, TÜRK, HACI MEHMET, ÇEŞME, DİLEK HACER, ŞİMŞEK, MELİH, ALKAN, ALPAY, TOPRAK, HÜSEYİN

Background: We aimed to investigate whether there is a difference between intrahepatic cholangiocarcinoma (IHCC) and liver metastases of gastrointestinal system (GIS) adenocarcinoma in terms of apparent diffusion coefficient (ADC) values. Patients and methods: From January 2018 to January 2020, we retrospectively examined 64 consecutive patients with liver metastases due to gastrointestinal system adenocarcinomas and 13 consecutive IHCC in our hospital's medical records. After exclusions, fifty-three patients with 53 liver metastases and 10 IHCC were included in our study. We divided the patients into two groups as IHCC and liver metastases of GIS adenocarcinoma. For mean apparent diffusion coefficient (ADCmean) values, the region of interests (ROI) was placed in solid portions of the lesions. ADCmean values of groups were compared. Results: The mean age of IHCC group was 62.50 ± 13.49 and mean age of metastases group was 61.15 ± 9.18. ADCmean values were significantly higher in the IHCC group compared to the metastatic group (p < 0.001). ROC curves method showed high diagnostic accuracy (AUC = 0.879) with cut-off value of < 1178 x 10-6 mm2/s for ADCmean (Sensitivity = 90.57, Specificity = 70.0, positive predictive value [PPV] = 94.1, negative predictive value [NPV] = 58.3) in differentiating adenocarcinoma metastases from IHCC. Conclusions: The present study results suggest that ADC values have a potential role for differentiation between IHCC and GIS adenocarcinoma liver metastases which may be valuable for patient management.

2018-01-01, MEHDI, Elnur, Aralasmak, AYŞE, Toprak, HÜSEYİN, Yildiz, Seyma, Kurtcan, SERPİL, Kolukisa, MEHMET, Asil, TALİP, Alkan, ALPAY, ARALAŞMAK, AYŞE, TOPRAK, HÜSEYİN, YILDIZ, ŞEYMA, KURTCAN, SERPİL, KOLUKISA, MEHMET, ASİL, TALIP, ALKAN, ALPAY

Background: Craniocervical Dissections (CCD) are a crucial emergency state causing 20% of strokes in patients under the age of 45. Although DSA (digital substraction angiography) is regarded as the gold standard, noninvasive methods of CT, CTA and MRI, MRA are widely used for diagnosis. Aim: Our aim is to illustrate noninvasive imaging findings in CCD. Conclusion: Emphasizing on diagnostic pitfalls, limitations and mimicking diseases.