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MİRAPOĞLU, SEMİH LÜTFİ

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MİRAPOĞLU
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SEMİH LÜTFİ
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Now showing 1 - 3 of 3
  • Publication
    Open Access
    Does ozone administration have a protective or therapeutic effect against radiotherapy-induced testicular injury?
    (2019-03-01) AYDOĞDU, İBRAHİM; İLBEY, YUSUF ÖZLEM; ÇOBAN, GANİME; EKİN, RAHMİ GÖKHAN; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALİ; KIZILTAN, HURİYE ŞENAY; EKİN, ZÜBEYDE YILDIRIM; SILAY, MESRUR SELÇUK; SEMERCİ, MEHMET BÜLENT; AYDOĞDU, İBRAHİM; ÇOBAN, GANİME; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALI; KIZILTAN, HURİYE ŞENAY
    Objective: We investigate the protective and therapeutic effects of ozone therapy (OT) in radiotherapy (RT)‑induced testicular damage. Methods: Thirty healthy adult male Wistar rats divided into five groups consisting of six animals each as follows: (1) Control (C), (2) RT, (3) OT, (4) OT + RT, and (5) RT + OT group. Histopathological findings, Johnsen scores, thiobarbituric acid‑reactive substances (TBARS), glutathione (GSH), superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) levels were evaluated. Results: RT caused a significant decrease in testicular weight and Johnsen score compared to the control group. In addition, TBARS level was significantly higher, whereas GSH, SOD, catalase, and GPx levels were significantly lower in the RT group when compared to the control group. Pre and postRT OT significantly increased GSH, SOD, catalase, and GPx levels and decreased TBARS level. Furthermore, testicular weight and Johnsen score were increased with OT. Conclusions: The present study showed that OT is protective and therapeutic in radiation‑induced testicular damage. OT may be beneficial to the patients who underwent RT.
  • Publication
    Metadata only
    Perforated appendicitis in children: antimicrobial susceptibility and antimicrobial stewardship
    (2018-09-01) TÜREL, ÖZDEN; MİRAPOĞLU, SEMİH LÜTFİ; GÜLTEPE, BİLGE; TÜREL, ÖZDEN; MİRAPOĞLU, SEMİH LÜTFİ; SÜMBÜL, BİLGE
  • Publication
    Metadata only
    Buschke-Löwenstein tumor of childhood presentation of three cases
    (2015-10-11) AYDOĞDU, İBRAHİM; UZUN, ERSAN; KILINCASLAN, HUSEYIN; MİRAPOĞLU, SEMİH LÜTFİ; AYDOĞDU, İBRAHİM; MİRAPOĞLU, SEMİH LÜTFİ
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