Person: KUTLU, NURETTİN ONUR
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- PublicationMetadata onlyA Rare Presentation of Neurobrucellosis in a 6-Year-Old Pediatric Patient with Sagittal Sinus Thrombosis(2020-10-01T00:00:00Z) TÜREL, Özden; KUTLU, NURETTİN ONUR; YEŞİLBAŞ, Osman; Yozgat, Can Yilmaz; DÜNDAR, TOLGA TURAN; BURSAL DURAMAZ, BURCU; UZUNER, SELÇUK; ABDİLLAHİ, FATOUMA KHALİF; TÜREL, ÖZDEN; UZUNER, SELÇUK; BURSAL DURAMAZ, BURCU; DÜNDAR, TOLGA TURAN; SEYİTHANOĞLU, MEHMET HAKAN; YEŞİLBAŞ, OSMAN; KUTLU, NURETTİN ONURBrucellosis is one of the most common zoonosis worldwide. It is still endemic in many regions of the world. A 6-year-old female was admitted to the emergency department (ED) due to a sudden change in consciousness, urinary incontinence, vomiting, and difficulty in walking. Neurological examination demonstrated abducens nerve paralysis, mild-to-moderate motor deficit in hemiparesis in the left arm. Brain magnetic resonance imaging showed a hemorrhagic focus at the right frontal lobe and thrombosis in the superior sagittal sinus of the brain. The diagnosis of neurobrucellosis was confirmed by identifying Brucella spp. in the blood culture on the day 6 of pediatric intensive care unit admission; thus, trimethoprim-sulfamethoxazole and rifampicin, and ceftriaxone were promptly initiated. Despite neuroprotective management and acetazolamide, the patient-s neurological problems and high intracranial pressure (ICP) persisted. An external ventricular drainage tube and a Codman ICP monitor were placed to be on the consent vigilance of the patient-s neurological condition. The patient-s ICP continued to increase despite the current treatment regimen; therefore, a decompressive bitemporal craniectomy was performed. The ICP level of the patient returned to its normal range immediately after the craniectomy. The patient did not have any notable neurologic sequelae at the first-year follow-up. Neurobrucellosis is a rare complication of systemic brucellosis and may present as meningitis, encephalitis, myelitis, radiculitis, and/or neuritis. Herein, we describe a six-year-old girl with brucellosis complicated with cerebral vein thrombosis. This case illustrates the need for close monitoring of patients with unexplained neurological signs or symptoms for brucellosis in endemic areas.
- PublicationMetadata onlyPosterior reversible encephalopathy syndrome in children: a case series(2016-12-01) Emeksiz, Serhat; Kutlu, NURETTİN ONUR; Caksen, Huseyin; Alkan, Gulsum; Yikmaz, Hulya Seker; Tokgoz, Huseyin; KUTLU, NURETTİN ONURPosterior reversible encephalopathy syndrome is characterized by hypertension, seizure, headache, clouding of consciousness, and visual disturbance, and is diagnosed in the presence of typical lesions on magnetic resonance imaging. We retrospectively evaluated five patients who were diagnosed as having posterior reversible encephalopathy syndrome and followed up in Meram Medical Faculty, Pediatric Intensive Care and Hematology wards, between January 2010 and January 2014. We reviewed the demographic and clinical data, and neuroimaging findings. The primary diseases of the subjects included acute lymphocytic leukemia (n=2), Henoch-Scholein purpura (n=1), systemic lupus erythematous (n=1), and acute poststreptococcal glomerulonephritis (n=1). The mean age was 10 +/- 4.58 years (range, 5-14 years). Acute elevation of blood pressure was found in all patients (n=5). Initial neurologic manifestations included seizure, clouding of consciousness, headache, and visual disturbance. After the diagnosis was made through clinical evaluations and magnetic resonance imaging, complete clinical recovery was obtained in all patients with the appropriate therapeutic approach. In conclusion, posterior reversible encephalopathy syndrome should be considered in the differential diagnosis of patients who present with encephalopathy and underlying diseases such as nephritis, vasculitis, malignancy accompanied by hypertension, and a history of use of medication.
- PublicationMetadata onlyClinical significance of human metapneumovirus in refractory status epilepticus and encephalitis case report(2015-12-06T00:00:00Z) VEHAPOĞLU TÜRKMEN, AYSEL; TÜREL, ÖZDEN; UYGUR ŞAHİN, TÜRKAN; KUTLU, NURETTİN ONUR; İŞCAN, AKIN; VEHAPOĞLU TÜRKMEN, AYSEL; TÜREL, ÖZDEN; UYGUR ŞAHİN, TÜRKAN; KUTLU, NURETTİN ONUR; İŞCAN, AKIN
- PublicationOpen AccessThe role of plasma exchange in acute liver failure of autoimmune etiology(2021-03-01T00:00:00Z) Gokce, Selim; Cermik, Banu Bal; KUTLU, NURETTİN ONUR; Ocak, Ilhan; KUTLU, NURETTİN ONURBackground: Autoimmune hepatitis (AIH) is characterized by increased immunoglobulin G (IgG) levels, the presence of autoantibodies, and various degrees of lymphocyte predominant inflammation and fibrosis histologically. Immunosuppressive therapy induces remission in approximately 80% of those affected. However, liver transplantation is indicated in patients with acute liver failure with encephalopathy at presentation. Liver supporting systems, including plasma exchange (PE) allow bridging patients to transplantation or spontaneous recovery in the setting of liver failure. The role of these systems has not been assessed in children with liver failure of autoimmune etiology. Case: Herein, we report three cases of AIH with fulminant presentation, with marked symptom resolution with PE as an adjunct therapeutic option to immunosuppressive treatment. Conclusion: In the setting of AIH, PE may have a special therapeutic role by removing autoantibodies and cytokines, therefore preventing further liver damage and decompensation, and allowing time for recovery.
- PublicationMetadata onlyMisdiagnosis of Bupropion Intoxication(2015-09-01) KUTLU, NURETTİN ONUR; KUTLU, NURETTİN ONUR
- PublicationOpen AccessClinical Significance of Human Metapneumovirus in Refractory Status Epilepticus and Encephalitis: Case Report and Review of the Literature(2015-01-01) VEHAPOGLU, Aysel; Turel, Ozden; SAHIN, Turkan Uygur; Kutlu, NURETTİN ONUR; ISCAN, Akjn; VEHAPOĞLU TÜRKMEN, AYSEL; TÜREL, ÖZDEN; KUTLU, NURETTİN ONUREncephalitis is a complex neurological disease that is associated with significant morbidity and mortality, and the etiology of the disease is often not identified. Human metapneumovirus (hMPV) is a common cause of upper and lower respiratory tract infections in children. Few reports are available showing possible involvement of hMPV in development of neurologic complications. Here, we describe an infant, the youngest case in literature, with refractory status epilepticus and severe encephalitis in whom hMPV was detected in respiratory samples and review diagnostic workup of patient with encephalitis.
- PublicationMetadata onlyYurdakök Pediatri(2017-04-01) KUTLU, NURETTİN ONUR; KUTLU, NURETTİN ONUR
- PublicationUnknownÇocuklarda Anamnezden Tanıya(2016-05-01) KUTLU, NURETTİN ONUR; KUTLU, NURETTİN ONUR
- PublicationMetadata onlyCardiopulmonary Resuscitation in Children With In-Hospital and Out-of-Hospital Cardiopulmonary Arrest Multicenter Study From Turkey(2015-11-01) Kendirli, Tanil; Erkek, Nilgun; Koroglu, Tolga; Yildizdas, Dincer; Bayrakci, Benan; Guzel, Ahmet; Citak, Agop; Demirkol, Demet; Agin, Hasan; Arslankoylu, Ali Ertug; Kutlu, NURETTİN ONUR; Tuygun, Nilden; Paksu, Muhammet Sukru; Anil, Ayse Berna; Kalkan, Gokhan; Duman, Murat; Dundaroz, Rusen; Asilioglu, Nazik; Yaman, Ayhan; Odek, Caglar; Tekin, Deniz; Dursun, Oguz; Sevketoglu, Esra; Kesici, Selman; Ates, Can; Gordu, Zulfikar; Yilmaz, Hayri Levent; Ince, Erdal; Karabocuoglu, Metin; KUTLU, NURETTİN ONURObjectives The objectives of this study were to determine the causes, location of cardiopulmonary arrest (CPA) in children, and demographics of cardiopulmonary resuscitation (CPR) in Turkish pediatric emergency departments and pediatric intensive care units (PICUs) and to determine survival rates and morbidities for both in-hospital and out-of-hospital CPA.