Person: UZUNER, SELÇUK
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Publication Open Access The relationship between severity of disease and vitamin D levels in children with atopic dermatitis(2017-01-01) Su, Ozlem; BEHALI, Anil Gulsel; DEMIR, Aysegul Dogan; OZKAYA, Dilek Biyik; Uzuner, SELÇUK; Dizman, DİDEM; Onsun, NAHİDE; SU KÜÇÜK, ÖZLEM; UZUNER, SELÇUK; DİZMAN, DİDEM; ONSUN, NAHIDEIntroduction: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disorder. Vitamin D is a liposoluble vitamin synthesized mainly in the skin. Vitamin D has several effects on the skin. Aim: To assess the serum level of vitamin D in children with AD and determine its relation to AD severity. Material and methods: Sixty patients with AD were enrolled in the study. We evaluated disease severity using the SCORing Atopic Dermatitis (SCORAD) index. The control group consisted of 37 healthy subjects. Results: The mean serum concentration of 25(OH)D3 in patients with AD was not statistically different from control subjects (p = 0.065). The vitamin D level was significantly lower in moderate and severe AD compared with mild AD, and this difference was statistically significant (p = 0.001 and p = 0.004). Vitamin D showed a negative correlation with serum total IgE levels (p = 0.007). There was no significant correlation between total IgE levels and SCORAD scores (p = 0.089). Conclusions: This study suggests that a low serum vitamin D level is inversely associated with severity of AD in children. Vitamin D has not been included in the routine treatment of AD because of the conflicting results of various studies. Thus, there is a need for more detailed and prospective studies.Publication Metadata only Two Siblings with Hyper IGE Syndrome Presenting with Molloscum contagiosum Infection and Recurrent Pneumonia(2014-05-10T00:00:00Z) KÜÇÜK, ÖZLEM SU; ARI, ENGİN; DOĞAN DEMİR, AYŞEGÜL; DÖNMEZ, TUĞRUL; UZUNER, SELÇUK; ÇAKIR, ERKAN; TÜREL, ÖZDEN; TÜRK, İBRAHİM; DOĞAN DEMİR, AYŞEGÜL; UZUNER, SELÇUK; ÇAKIR, ERKAN; SU KÜÇÜK, ÖZLEM; TÜREL, ÖZDENPublication Metadata only Two siblings with hyper IgE syndrome presenting with molloscum contagıosum ınfectıon and recurrent pneumoniae,(2015-05-06T00:00:00Z) Arı, Engin; Doğan Demir, Ayşegül; Sönmez, Tuğrul; Uzuner, Selçuk; Çakır, Erkan; Türel, Özden; Küçük, Özlem Su; DOĞAN DEMİR, AYŞEGÜL; UZUNER, SELÇUK; ÇAKIR, ERKAN; TÜREL, ÖZDEN; SU KÜÇÜK, ÖZLEM