Person: UZUNER, SELÇUK
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Publication Open Access Hematological indices for differential diagnosis of Beta thalassemia trait and iron deficiency anemia.(2014-01-01) OZGURHAN, G; DEMIR, AD; Uzuner, SELÇUK; NURSOY, MUSTAFA ATİLLA; TURKMEN, S; KACAN, A; VEHAPOĞLU TÜRKMEN, AYSEL; UZUNER, SELÇUK; NURSOY, MUSTAFA ATİLLABackground. The two most frequent types of microcytic anemia are beta thalassemia trait (𝛽-TT) and iron deficiency anemia (IDA). We retrospectively evaluated the reliability of various indices for differential diagnosis of microcytosis and 𝛽-TT in the same patient groups. Methods. A total of 290 carefully selected children aged 1.1–16 years were evaluated. We calculated 12 discrimination indices in all patients with hemoglobin (Hb) values of 8.7–11.4 g/dL. None of the subjects had a combined case of IDA and 𝛽-TT. All children with IDA received oral iron for 16 weeks, and HbA2 screening was performed after iron therapy. The patient groups were evaluated according to red blood cell (RBC) count; red blood distribution width index; the Mentzer, Shine and Lal, England and Fraser, Srivastava and Bevington, Green and King, Ricerca, Sirdah, and Ehsani indices; mean density of hemoglobin/liter of blood; and mean cell density of hemoglobin. Results. The Mentzer index was the most reliable index, as it had the highest sensitivity (98.7%), specificity (82.3%), and Youden’s index (81%) for detecting 𝛽-TT; this was followed by the Ehsani index (94.8%, 73.5%, and 68.3%, resp.) and RBC count (94.8%, 70.5%, and 65.3%). Conclusion.The Mentzer index provided the highest reliabilities for differentiating 𝛽-TT from IDA.Publication Open Access A Rare Presentation of Acquired Laryngomalacia and Tracheomalacia in a Child Associated with Apricot Sulfurization(2020-12-01T00:00:00Z) Vehapoğlu Türkmen, Aysel; Çakır, Erkan; Uzuner, Selçuk; Çalım, Ömer Faruk; Yazan, Hakan; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIR, ERKAN; UZUNER, SELÇUK; ÇALIM, ÖMER FARUK; YAZAN, HAKANSulfur fumigation has come to replace traditional sun drying methods for drying fruits over the years around the world as it is a cheaper and faster method because of its pesticidal and anti-bacterial properties. We report the case of an 11-year-old boy with acquired severe biphasic stridor who was exposed to extremely high concentrations of sulfur dioxide (SO2) during apricot sulfurization processes with his mother. The patient's bronchoscopy revealed severe glottic and subglottic damage. Exposure to SO2 is a health risk, particularly for individuals who are sulfide-sensitive, especially in childhood. The pulmonary epithelium may be directly injured by inhaled toxic substances at various levels of the respiratory system. To the best of our knowledge, this is the first case reported of acquired airway damage associated with sulfurization in a pediatric patient without a known history of any respiratory disease or symptoms.Publication Open Access The different cutaneous presentations in three cases of Kawasaki disease as confounding factor of diagnosis(2016-09-01) DEMIR, Aysegul Dogan; GOKNAR, Nilufer; Uzuner, SELÇUK; Vehapoglu, Aysel; Saritas, Turkay; OKTEM, Faruk; UZUNER, SELÇUK; VEHAPOĞLU TÜRKMEN, AYSELWe report three paediatric cases of Kawasaki disease (KD). Erythema multiforme (EM) was the presenting cutaneous feature in two patients, with young age (43 days old), macular rash and meningitis in the third patient. Diagnosis of KD was difficult due either to initial misdiagnosis of drug eruption, incomplete presentation, or the young age of the patient. Clinicians should be aware of these cutaneous presentations to prevent KD complications.