Person: MERAL, İSMAİL
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Publication Metadata only Kardiyovasküler Hastalıklarda Biyotinidaz ve TCA Enzim Aktivitelerinin İncelenmesi(2023-07-09) Sarıkaya U.; Çimen Y. A.; Taşlıdere B.; Selek Ş.; Açıkgöz N.; Meral İ.; SARIKAYA, UFUK; ÇİMEN, YASİN ALİ; TAŞLIDERE, BAHADIR; SELEK, ŞAHABETTİN; AÇIKGÖZ, NUSRET; MERAL, İSMAİLPublication Metadata only Raftlin, presepsin levels and thiol-disulfide homeostasis in acute appendicitis: A pilot study(2018-11-01) KOÇYİĞİT, ABDÜRRAHİM; ERSOY, YELİZ EMİNE; SELEK, ŞAHBETTİN; SÜMBÜL, BİLGE; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; MERAL, İSMAİL; YİĞİT, MEHMET; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; MERAL, İSMAİL; SÜMBÜL, BİLGE; SELEK, ŞAHABETTİN; ERSOY, YELIZ EMINEObjective: To investigate some of the new inflammatory and oxidative stress markers in acute appendicitis.Publication Metadata only Sulodexide protected the heart against ischemia/reperfusion injury by reducing oxidative stress, inflammation, and apoptosis in the isolated rat heart(2022-11-17) ÜSTÜNOVA S.; AKSOY R.; BULUT H.; KILIÇ A.; MERAL İ.; RABUŞ M. B.; BOZKURT A. K.; KÖKSAL C.; ÜSTÜNOVA, SAVAŞ; KILIÇ, AYSU; MERAL, İSMAİL; KÖKSAL, CENGİZPublication Metadata only Effects of Thymoquinone On Erythrocyte Aggregation Kinetics: An In Vitro Study(2022-01-01T00:00:00Z) ÜSTÜNOVA, SAVAŞ; Uyuklu, Mehmet; MERAL, İSMAİL; ÜSTÜNOVA, SAVAŞ; MERAL, İSMAİL© 2022, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.Erythrocyte aggregation is associated with a series of physio-pathological processes in body and according to this, current study was designed to examine how the thymoquinone (TQ) and a ggregation kinetics relation changes when the aggregation properties of erythrocyte suspensions are intervened using different approaches, such as changing the suspension environment or erythrocyte surface properties. Blood samples from 40 male Wistar albino rats (three months old weighing 250-300 g) were randomly divided into four groups, as 1) whole blood (control), 2) 1/2 dilution (plasma was diluted with PBS), 3) dextran 500 (1% dextran 500 was dissolved in plasma) and 4) glutaraldehyde. Blood samples were taken from abdominal aorta under anesthesia. The erythrocyte suspensions were incubated at 37°C for one hour in the absence or presence of TQ, with a final concentration of 1 mg/ml. Then, the electrical properties of erythrocyte suspensions were recorded, and the electrical capacitance was monitored using an inductance, capacitance, and resistance meter (LCR meter) at 100 kHz. It was found that TQ incubation decreased the aggregation index in control and dextran groups while increased it in 1/2 dilution and GA groups. It was also found that TQ incubation increased the time constant in whole blood and dextran while decreased it in 1/2 dilution and GA. The TQ can normalize the altered erythrocyte aggregation responses in both ways that is, it decreases the increased aggregation or increases the decreased aggregation. Therefore, it may have very critical role in rouleaux formation-induced circulatory disorders.Publication Metadata only Serum Electrolyte Values and Blood Oxidative Stress Parameters in Patients with Focal and Generalized Epilepsy(2023-02-01) Sarı G.; Kılıç A.; Uslu F.; Selek Ş.; Üstünova S.; Meral İ.; KILIÇ, AYSU; ÜSTÜNOVA, SAVAŞ; MERAL, İSMAİL