Person: YILMAZ, ONUR
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Publication Metadata only Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment(2019-01-01) ÖZTÜRK, AHMET; Şahan, Ebru; MIRÇIK, ALİ BARLAS; DEVECİ, ERDEM; YILMAZ, ONUR; KIRPINAR, İSMET; ÖZTÜRK, AHMET; ŞAHAN, EBRU; MIRÇIK, ALİ BARLAS; DEVECİ, ERDEM; YILMAZ, ONUR; KIRPINAR, İSMETObjective: Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods: Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital psychiatry inpatient unit retrospectively included in the study. Control group consisted of 48 hospital workers with no known disease. Complete blood count, Hamilton Depression Rating Scale (HAM-D) and Clinical Global Impression-Severity Scale (CGI-S) scores at admission and at discharge were noted and compared for the patient group. Discussion: MPV of depressed patients was higher than controls. When we look at admission and discharge scores of clinical scales, decrement is statistically significant for both HAM-D and CGI-S. There was decline both in MPV and NLR which were both statistically significant. Conclusion: Decreasing MPV and NLR values with the treatment of depression confirm the involvement of inflammatory processes in the pathophysiology of depression.Publication Metadata only Childhood traumas in patients with bipolar disorder: association with alexithymia and dissociative experiences(2016-01-01) Yilmaz, ONUR; Ates, M. Alpay; Semiz, U. Basar; TÜTÜNCÜ, Recep; Bez, Yasin; ALGÜL, Ayhan; BALIBEY, Hakan; BAŞOĞLU, Cengiz; EBRİNÇ, Servet; ÇETİN, Mesut; YILMAZ, ONURObjective: The number of studies investigating the traumatic events experienced during childhood period in patients with bipolar disorder (BD) are limited and to our knowledge no previous study was conducted about alexithymia and dissociative experiences of these patients as well. Besides investigation of childhood traumas and associated dissociative and alexithymic properties, identification of the differences between BD patients with and without childhood trauma (CT) was aimed in this study. Methods: Among the admissions to the psychiatry outpatient clinic, 70 BD patients and 70 healthy control subjects were included into the study. Structured Clinical Interview for DSM-IV Axis-I Disorders, Dissociative Experiences Scale (DES), Childhood Trauma Questionnaire (CTQ) and Toronto Alexithymia Scale (TAS-20) were administered. Results: Mean subscale and total scores of patients with BD in both CTQ and TAS-20, and mean DES score were found to be significantly higher than healthy control subjects. Psychopathological acts, number of episodes and suicide attempts were higher in the BD patients with childhood trauma history than that of the BD patients without any history of childhood trauma. Additionally, positive correlations were found between -sexual abuse- and alexithymia total score along with -difficulty identifying feelings- subscale score. Moreoever, mean DES score was also found to be positively correlated with -difficulty identifying feelings- subscale score, -difficulty to describe feelings- subscale score, alexithymia total score, and episode frequency. Conclusion: These results highlight the importance of protective mental health in the treatment of BD and reveal that childhood traumas should be questioned when evaluating patients especially with the diagnosis of BD.Publication Metadata only Oxidative stress and inflammatory response in patients with psoriasis; is there any relationship with psychiatric comorbidity and cognitive functions?(2019-01-01) DEVECİ, ERDEM; Kocacenk, Tuba; ŞAHAN, EBRU; YILMAZ, ONUR; ÖZTÜRK, AHMET; KIRPINAR, İSMET; DEVECİ, ERDEM; ŞAHAN, EBRU; YILMAZ, ONUR; ÖZTÜRK, AHMET; KIRPINAR, İSMETPublication Metadata only Essential Tremor and Alexithymia(2018-10-01) ŞENGÜL, YILDIZHAN; ŞENGÜL, HAKAN SERDAR; GÖKÇAL, ELİF; ÜSTÜN, İSMET; ÖZTÜRK, AHMET; YILMAZ, ONUR; YILDIZ, GÜLSEN; ŞENGÜL, YILDIZHAN; GÖKÇAL, ELİF; ÜSTÜN, İSMET; ÖZTÜRK, AHMET; YILMAZ, ONURPublication Metadata only Alkol Kullanım Bozukluklarına Yaklaşım(2018-07-01) YILMAZ, ONUR; DEVECİ, ERDEM; ÖZTÜRK, AHMET; YILMAZ, ONUR; DEVECİ, ERDEM; ÖZTÜRK, AHMETPublication Metadata only Şizofreni Aile Hekimliği İçin Bir Gözden Geçirme(2018-07-01) DEVECİ, ERDEM; YILMAZ, ONUR; ÖZTÜRK, AHMET; DEVECİ, ERDEM; YILMAZ, ONUR; ÖZTÜRK, AHMETPublication Metadata only The relationship of insight with obsessive beliefs and metacognition in obsessive compulsive disorder(2020-01-01T00:00:00Z) YILMAZ, Onur; BOYRAZ, Rabia Kevser; Kurtulmus, Ayse; PARLAKKAYA, FATMA BÜŞRA; ÖZTÜRK, AHMET; YILMAZ, ONUR; BOYRAZ, RABIA KEVSER; PARLAKKAYA, FATMA BÜŞRA; ÖZTÜRK, AHMETPublication Metadata only Esansiyel Tremor Hastalarında Yüz Duygu Tanıma(2018-12-01) Şengül, YILDIZHAN; TUNÇ, ABDULKADİR; YILMAZ, ONUR; ÖZTÜRK, AHMET; ŞENGÜL, YILDIZHAN; TUNÇ, ABDULKADIR; YILMAZ, ONUR; ÖZTÜRK, AHMETPublication Metadata only Temperament and Character Differences of Patients with Polycystic Ovary Syndrome(2019-01-01) ÖZTÜRK, AHMET; YÜKSEL, KADRİYE BERİL; KABİL KUCUR, SUNA; DEVECİ, ERDEM; YILMAZ, ONUR; ÖZTÜRK, AHMET; DEVECİ, ERDEM; YILMAZ, ONURAim: There is an unclear relationship between Polycystic Ovary Syndrome and psychiatric disorders including anxiety and depression. We aimed to evaluate temperamental and personal characteristics of patients with PCOS.Publication Metadata only Does psychotherapy improve alexithymia? A comparison study among patients with mild or moderate depression(2019-11-01) YILMAZ, ONUR; Mircik, Ali Barlas; Kunduz, Merve; Combas, Muge; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMET; YILMAZ, ONUR; MIRÇIK, ALİ BARLAS; ÖZTÜRK, AHMET; DEVECİ, ERDEM; KIRPINAR, İSMETBackground: Alexithymia is reported to be a risk factor for depression. Psychotherapy is efficient for treatment of depression. Yet, the effect of psychotherapies on alexithymia is poorly understood. Objectives: We aimed to compare Cognitive Behavioral Therapy (CBT), Existential Psychotherapy (ExP) and Supportive Counseling (SUP) for therapeutic efficacy and effect on alexithymia in depression. Methods: There were 22 patients for each patient group. Sessions were performed as eight consecutive weekly and following two monthly boosters. Sixty six healthy controls were added. Prior to the sessions, patients received Sociodemographic Data Form, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-1), Hamilton Depression Rating Scale (HDRS) and 20-item Toronto Alexithymia Scale (TAS-20). The control group received Sociodemographic Data Form, SCID-1 and TAS-20. Patients additionally received HDRS and TAS-20 after their weekly and booster sessions. Results: Patients- mean TAS-20 score was greater than of controls, however, it did not have a significant change throughout the study. Mean HDRS scores of ExP and CBT groups were lower than SUP group at the end. Discussion: Alexithymia did not improve with psychotherapy. The exception was effect of ExP on externally oriented thinking. Psychotherapies all improved depression. CBT and ExP were more helpful than SUP.