Person: KALKAN, SENAD
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Publication Metadata only C-reactive protein and Procalcitonin levels in Prostate Cancer.(2020-12-16T00:00:00Z) Kalkan, Senad; Çalışkan, Selahattin; İLKTAÇ, ABDULLAH; KALKAN, SENADPublication Metadata only Long term results of augmentation cystoplasty and urinary diversion in multiple sclerosis(2019-06-01T00:00:00Z) KALKAN, Senad; Jaffe, William I.; Simma-Chiang, Vannita; Li, Eric S. W.; Blaivas, Jerry G.; KALKAN, SENADIntroduction: There is a paucity of data about augmentation cystoplasty (AC) in multiple sclerosis (MS) patients with refractory lower urinary tract symptoms (LUTS). The aim of this study is to evaluate the long term outcomes and morbidity of these procedures in MS patients.Publication Metadata only Systematic versus cognitive targeted biopsy: evaluation of parameters related to clinically significant prostate cancer and comparison of detection rates(2022-10-01) Ersöz C.; İlktaç A.; Kalkan S.; Kayalı Y.; Akbulut H.; Toprak H.; Doğan B.; ERSÖZ, CEVPER; İLKTAÇ, ABDULLAH; KALKAN, SENAD; AKBULUT, HABİB; TOPRAK, HÜSEYİN; DOĞAN, BAYRAMPublication Open Access High D-dimer levels are associated with prostate cancer(2020-05-01T00:00:00Z) KALKAN, Senad; Caliskan, Selahattin; KALKAN, SENADProstate cancer is one of the most common types of cancer among men in the world1 and a significant health problem in developed and developing countries2 . The association between cancer and hemostasis has been shown in several studies3 . The main risk factors for coagulation activation and thrombosis are aging and malignancy4 . The increased risk of thrombosis in cancer patients may be associated with high levels of coagulation markers (fibrinogen), and thrombogenesis markers (D-dimer) are likely evidence of this process5 . Fibrinogen is an acute-phase protein that is mainly synthesized by hepatocytes and converted into insoluble fibrin by activated thrombin. It is also an important indicator of the coagulation system6 . The plasma fibrinogen level increases in some circumstances, such as malignancy and systemic inflammation. D-dimer is a degradation product of fibrin which is produced by plasmin-induced fibrinolytic activity7 . It is a biomarker that indicates the activation of hemostasis and fibrinolysis. Elevated plasma levels may be associated with some scenarios such as cancer, pregnancy, infectious diseases, trauma, surgery, and venous thromboembolism. When fibrinogen levels are increased, they are deemed to be an unfavorable prognostic factor in some malignancies, such as those of the digestive system, gynecologic malignancies, urologic neoplasms, and soft tissue sarcomas6 . A high level of D-dimer is a prognostic factor associated with increased mortality risk in patients with brain tumors, lymphomas, breast, lung, stomach, colorectal, pancreatic, and prostate cancers7 . We investigated the levels of D-dimer and fibrinogen in patients with prostate cancer and benign prostate hyperplasia.Publication Metadata only Mesh related vesıcoperitoneal fistula presenting with urinary ascites. A case report.(2018-11-01) İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; DOĞAN, BAYRAM; KALKAN, SENAD; ERSÖZ, CEVPER; DOĞAN, BAYRAM; KALKAN, SENADPublication Metadata only Gunshot injury to the penis in a patient with penile prosthesis: a case report.(2011-09-01T00:00:00Z) ÖZTÜRK, MI; Ilktaç, ABDULLAH; KOCA, O; KALKAN, SENAD; KAYA, C; KARAMAN, MI; İLKTAÇ, ABDULLAH; KALKAN, SENADPublication Open Access Mesh related vesico-peritoneal fistula presenting with urinary ascites: A case report(2019-03-01T00:00:00Z) İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; DOĞAN, BAYRAM; KALKAN, Senad; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; DOĞAN, BAYRAM; KALKAN, SENADVesicoperitoneal fistula is a very rare entity of epithelialized communication between peritoneal cavity and bladder.1 It results in accumulation of urine in peritoneal cavity and causes elevated urea and creatinine levels mimicking acute renal failure. Incisional hernia is common complication of abdominal surgery and often repaired with non-absorbable mesh.2 Using dual mesh can reduce mesh related complications but migration to adjacent organs can still happen and cause severe complications. Here we present a case of mesh related vesico-peritoneal fistula presenting with urinary ascites 2 years after incisional hernia repair.Publication Metadata only MESH SLING COMPLICATIONS: FEASIBILITY OF ACCESSING DATA FROM PATIENTS INVOLVED IN MESH LITIGATION(2019-04-01T00:00:00Z) Blaivas, Jerry G.; Chughtai, Bilal; Li, Eric S. W.; Kalkan, Senad; Dayan, Linda; Prishtina, Learta; Mathew, Joel; KALKAN, SENADPublication Metadata only AUTOLOGOUS RECTUS FASCIAL PUBOVAGINAL SLING AFTER VAGINOPLASTY: AN OLD TRICK FOR A NEW PROBLEM(2019-04-01T00:00:00Z) Purohit, Rajveer; Blaivas, Jerry G.; Kalkan, Senad; KALKAN, SENADPublication Open Access Comparison of Scoring Systems in Predicting Success of Percutaneous Nephrolithotomy(2019-01-01T00:00:00Z) AKÇAY, MUZAFFER; Tosun, Muhammed; GEVHER, FATİH; KALKAN, Senad; ERSÖZ, CEVPER; Kayali, Yunus; Tepeler, Abdulkadir; AKÇAY, MUZAFFER; TOSUN, MUHAMMED; GEVHER, FATİH; KALKAN, SENAD; ERSÖZ, CEVPER; KAYALI, YUNUSBackground: Scoring systems are useful to inform the patients about the success and complication rates of the operation prior the surgery. Aims: To determine the applicability of the popular scoring systems (Guy’s, stone size, tract length, obstruction, number of involved calices, and essence/stone density and Clinical Research Office of the Endourological Society) by means of examining preoperative data of patients treated with percutaneous nephrolithotomy. Study Design: Cross sectional study. Methods: We retrospectively reviewed files of the patients who had undergone percutaneous nephrolithotomy in our center between 2011 and 2015. Excluded from the study were patients aged <18 years, and those who were not assessed preoperatively with computed tomography. Preoperative computed tomography images of all patients were assessed by a single observer, and patients were graded based on three scoring system. Demographic data were analyzed along with perioperative data (operation, fluoroscopy, length of hospital stay, changes in hematocrit values, location, and number of access sites, stone-free and complication rates). Results: A total of 298 patients who had been treated with 300 procedures were enrolled into the study. Mean age, stone burden, number of stones, and density were 48.1±12.9 years, 663.5±442.8 mm2, 1.8±1.1 and 888.3±273 HU respectively. Scores of the cases based on Guy’s, stone size, tract length, obstruction, number of involved calices, and essence/stone density, and Clinical Research Office of the Endourological Society scoring system were calculated as 2, 7.6, and 222.1 points respectively. 81.6% of the patients were stonefree. Complications were detected in 30 (9.9%) patients. Based on receiver operating characteristic curve analysis a positive correlation was detected between success rate and scoring systems, i.e., Guy’s (p=<0.001, r=-0.309), stone size, tract length, obstruction, number of involved calices, and essence/stone density (p=<0.001, r=-0.295), and Clinical Research Office of the Endourological Society (p=<0.001, r=0.426). The Clinical Research Office of the Endourological Society scoring system had the highest predictive value. The sensitivity rates rates for Guy’s, Clinical Research Office of the Endourological Society and Stone scoring system were as 78.78%, 80% and 82.34% respectively. Conclusion: All of scoring systems predicted correctly the success of the percutaneous nephrolithotomy procedures. The Clinical Research Office of the Endourological Society scoring system had the highest predictive value. Keywords: Percutaneous nephrolitotomy, scoring methods, specificity and sensitivity, urinary calculi