2020-01-06T00:00:00Z, Karslıoglu, T, Karasu, AFG, Yildiz, PELİN, YILDIZ, PELİN

2016-09-01, Su, Ozlem, OZKAYA, Dilek Biyik, Emiroglu, NAZAN, Cengiz, FATMA PELİN, Bahali, ANIL GÜLSEL, Yildiz, PELİN, DEMIRKESEN, Cuyan, Onsun, NAHİDE, EMİROĞLU, NAZAN, SU KÜÇÜK, ÖZLEM, CENGİZ, FATMA PELIN, BAHALI, ANIL GÜLSEL, YILDIZ, PELİN, ONSUN, NAHIDE

ackground:: Pigmented purpuric dermatosis is a chronic skin disorder of unknown aetiology characterised by symmetrical petechial and pigmented macules, often confined to the lower limbs. The aetiology of pigmented purpuric dermatosis is unknown. Dermatoscopy is a non-invasive diagnostic technique that allows the visualisation of morphological features invisible to the naked eye; it combines a method that renders the corneal layer of the skin translucent with an optical system that magnifies the image projected onto the retina. Objectives:: The aim of this study is to investigate the dermatoscopic findings of pigmented purpuric dermatosis. Methods:: This study enrolled patients diagnosed histopathologically with pigmented purpuric dermatosis who had dermatoscopic records. We reviewed the dermatoscopic images of PPD patients who attended the outpatient clinic in the Istanbul Dermatovenereology Department at the Bezmialem Vakıf University Medical Faculty. Results:: Dermatoscopy showed: coppery-red pigmentation (97%, n = 31) in the background, a brown network (34%, n = 11), linear vessels (22%, n = 7), round to oval red dots, globules, and patches (69%, n = 22; 75%, n = 24; 34%, n = 11; respectively), brown globules (26%, n = 8) and dots (53%, n = 17), linear brown lines (22%, n = 7), and follicular openings (13%, n = 4). Conclusion:: To our knowledge, this is the first study to report the dermatoscopy of pigmented purpuric dermatosis. In our opinion, dermatoscopy can be useful in the diagnosis of pigmented purpuric dermatosis.

2017-07-01, Su, Ozlem, Emiroglu, NAZAN, Yildiz, PELİN, OZKAYA, Dilek Biyik, Bahali, ANIL GÜLSEL, Onsun, NAHİDE, EMİROĞLU, NAZAN, YILDIZ, PELİN, BIYIK ÖZKAYA, DİLEK, BAHALI, ANIL GÜLSEL, SU KÜÇÜK, ÖZLEM, ONSUN, NAHIDE

Background/ObjectivesSpitz nevi are melanocytic lesions with clinical, dermoscopic, and histopathologic presentations that may resemble those of melanoma. The evolution of Spitz nevi is a well-known feature. The objectives of this study were to investigate the clinical and dermoscopic features of Spitz nevi and define their evolution.

2014-08-01T00:00:00Z, HUQ, Gulben Erdem, Canberk, Sule, Oznur, Meltem, Yildiz, PELİN, Bahadir, Burak, BEHZATOĞLU, Kemal, YILDIZ, PELİN

Micropapillary carcinoma (MPC) is a rare aggressive tumor, which generally accompanies the primary carcinoma of the organ of its origin, while the pure form is extremely uncommon. Angiolymphatic involvement is widespread and a considerable proportion of the cases present with metastases. The current study presents eight pure MPC cases arising from the breast (n=3), urinary bladder (n=3), parotid gland (n=1) and lung (n=1, presenting with pericardial effusion), with the cytological findings. The eight patients included three female and five male cases aged between 48 and 74 years. The most common cytological findings were three-dimensional aggregates, cell clusters with angulated or scalloped borders, single cells with a columnar configuration and eccentric nuclei, and high-grade nuclear features. Histopathological sections showed accompanying in situ ductal carcinoma in the cases of MPC arising in the parotid gland and breast (n=3), and one case in the bladder exhibited only in situ MPC. The average follow-up period was 20 months (range, 6-54 months) and, during this period, three patients succumbed to the disease. At present, four patients are alive with disease and one patient is alive and disease-free. In conclusion, cytology is an important tool for the diagnosis and management of MPC.

2016-08-01, BAHALI, Anil G., Su, Ozlem, Biyik Ozkaya, DİLEK, Dizman, DİDEM, Yildiz, PELİN, Demirkesen, Cuyan, Onsun, NAHİDE, BAHALI, ANIL GÜLSEL, SU KÜÇÜK, ÖZLEM, BIYIK ÖZKAYA, DİLEK, DİZMAN, DİDEM, YILDIZ, PELİN, ONSUN, NAHIDE

2019-08-22T00:00:00Z, Yildiz, PELİN, Aung, PP, Milton, DR, Hruska, C, Ivan, D, Nagarajan, P, Tetzlaff, MT, Curry, JL, Torres-Cabala, C, Prieto, VG, YILDIZ, PELİN

2014-06-01T00:00:00Z, Yildiz, PELİN, Tosuner, ZEYNEP, Guneren, ETHEM, Demirkesen, Cuyan, YILDIZ, PELİN, TOSUNER, ZEYNEP, GÜNEREN, ETHEM

Primary cutaneous carcinosarcomas (CS) are extremely rare biphasic tumors mainly located on sun-exposed areas of the body. Two hypotheses-multiclonal (convergence) and monoclonal (divergence)-have been suggested for the evolution of these tumors. According to multiclonal hypothesis two or more stem cells of epithelial and mesenchymal origin give rise to these tumors, while a single totipotential cell differentiate into epithelial and mesenchymal components, either synchronously or metachronously according to monoclonal hypothesis. Cutaneous CSs are subdivided into two distinct groups as epidermal and adnexal CSs, due to their epithelial content. We present an interesting case of cutaneous adnexal CS, showing peripheral nerve sheath differentiation and having the spiradenocarcinoma component derived from spiradenoma. To the best of our knowledge, it is the first reported case of CS with these features in the literature.

2015-06-01, HASBAHCECI, Mustafa, Akcakaya, ADEM, Memmi, NAİM, TURKMEN, Ihsan, Cipe, Gokhan, Yildiz, PELİN, Arici, DİLEK SEMA, MUSLUMANOGLU, Mahmut, AKÇAKAYA, ADEM, MEMMİ, NAİM, YILDIZ, PELİN, ARICI, DILEK SEMA

Objective: The purpose of this study was to evaluate the accuracy of diffusion weighted magnetic resonance imaging (MRI) in preoperative assessment of metastatic lymph nodes of gastric cancer. Methods: A total of 23 gastric cancer patients with a mean age of 59.4±10.9 years were analyzed. Lymph nodes were grouped as perigastric lesser curvature (Group Ia), perigastric greater curvature (Group Ib), D1+/D2 lymph nodes (Group II). Identification of histologically metastatic lymph nodes by diffusion weighted MRI was regarded as the main outcome. Results: A total of 1,056 lymph nodes including 180 histologically proven metastatic lymph nodes were dissected. Although diffusion weighted MRI could identify the metastatic lymph nodes in 18 out of 23 patients (77.8%), only 69 of total 1,056 nodes (6.53%), either metastatic or non-metastatic, could be detected. There was no correlation between histopathology and diffusion weighted MRI with regard to lymph node groups (P>0.05 for all). Overall accuracy was calculated as 69.56, 65.21 and 52.17 for Groups II, Ib and Ia lymph nodes, respectively. Apparent diffusion coefficient (ADC) values could not be helpful to differentiate metastatic lymph nodes (P=0.673). Conclusions: Diffusion weighted MRI has low accuracy to detect or to differentiate metastatic and non-metastatic lymph nodes based on their ADC values in gastric cancer.

2019-04-01T00:00:00Z, Cengiz, FP, Kelahmetoglu, O, Guneren, E, Yildiz, PELİN, CENGİZ, FATMA PELIN, YILDIZ, PELİN, GÜNEREN, ETHEM

2021-03-01T00:00:00Z, Yildiz, PELİN, Aydin Ulgen, Ovgu, Yol, Cansu, Demirkesen, Cuyan, YILDIZ, PELİN