Person: YILDIZ, PELİN
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Publication Metadata only Current Approach to the Prognostic Parameters of Testicular Germ Cell tumors Accompanied by Our Cases(2020-08-01T00:00:00Z) Çoban, Ganime; Yıldız, Pelin; Sezal, Zeynep; Adıllı, Adile; Beşiroğlu, Mehmet; Akçay, Muzaffer; Gücin, Zühal; ÇOBAN, GANİME; YILDIZ, PELİN; BEŞİROĞLU, MEHMET; AKÇAY, MUZAFFER; GÜCİN, ZÜHALPublication Metadata only Histopathological Features of Paratesticular Solid Tumors: 5 Years Experience(2020-05-01T00:00:00Z) Çoban, Ganime; Yıldız, Pelin; Kıran, Tuğçe; Ersöz, Cevper; ÇOBAN, GANİME; YILDIZ, PELİN; KIRAN, TUĞÇE; ERSÖZ, CEVPERPublication Metadata only The role of diffusion-weighted MRI and contrast-enhanced MRI for differentiation between solid renal masses and renal cell carcinoma subtypes(2020-09-01T00:00:00Z) Serter, Asli; ONUR, MEHMET RUHİ; ÇOBAN, Ganime; YILDIZ, PELİN; Armagan, Abdullah; Kocakoc, Ercan; ÇOBAN, GANİME; YILDIZ, PELİNPurpose To assess the value of diffusion-weighted magnetic resonance imaging (DW-MRI) and contrast-enhanced MRI (CE-MRI) for differentiation between benign and malignant solid renal masses, renal cell carcinoma (RCC) subtypes, oncocytomas, and lipid-poor angiomyolipomas (LP-AML). Methods Minimum or lowest -apparent diffusion coefficient- (ADC(1)) and representative ADC values (ADC(2)) of 112 renal masses (n: 46 benign renal mass,n: 66 malignant renal mass) were measured on DW-MRI images (b50, 400, 800 s/mm(2)). Signal intensity (SI) measurements were performed in normal renal parenchyma and most avid enhanced area of the renal masses at precontrast, corticomedullary, and nephrographic phases on CE-MRI. Contrast enhancement rate (CER) and contrast enhancement index (CEI) values of renal masses were compared between benign-malignant renal masses and RCC subtypes, oncocytomas, and LP-AMLs. Results There was no significant difference between ADC(1), ADC(2)values, and SI of benign and malignant renal masses (p = 0.721,p = 0.255,p = 0.872). Mean ADC(1)and ADC(2)values of clear cell RCCs were significantly higher than nonclear cell RCCs (p = 0.005p = 0.002). Mean CER value of clear cell RCCs was significantly higher than nonclear cell RCCs in nephrographic phase (p = 0.003). Mean CEI values of clear cell RCCs were significantly higher than nonclear cell RCCs in the corticomedullary and nephrographic phase (p = 0.027 vs. 0.008). LP-AMLs were differentiated from other renal masses with wash-out phenomenon. Conclusion Combined usage of ADC, SI, CER, and CEI values may be useful for discrimination between RCC subtypes, oncocytomas, and lipid-poor AMLs.Publication Open Access Expression of transient receptor potential melastatin 4 in differential diagnosis of eosinophilic renal tumors(2021-11-01T00:00:00Z) ÇOBAN, GANİME; YILDIZ, PELİN; DOĞAN, BAYRAM; ŞAHİN, NURHAN; GÜCİN, ZÜHAL; ÇOBAN, GANİME; YILDIZ, PELİN; DOĞAN, BAYRAM; ŞAHİN, NURHAN; GÜCİN, ZÜHALImmunohistochemical and molecular studies to differentiate eosinophilic kidney tumors are gradually increasing. The present study investigated the role of transient receptor potential cation channel subfamily M member 4 (TRPM4), a non-selective cation channel associated with migration, proliferation and invasion in cancer cells, in this differentiation. The aim was to investigate the effectiveness of TRPM4 in differentiation of eosinophilic kidney tumors. The study included a total of 112 patients, including 97 eosinophilic kidney tumors with the diagnoses of 33 eosinophilic clear cell renal cell carcinoma (CCRCC), 35 eosinophilic chromophobe renal cell carcinoma (ChRCC), 8 papillary renal cell carcinoma type 2 (P2RCC), 21 renal oncocytoma (RO), as well as 15 papillary renal cell carcinoma type 1 to differentiate from P2RCC. For TRPM4, diffuse staining (>10%) was observed in 2 CCRCC, 15 ChRCC, 20 RO and 4 P2RCC cases. There was a significant difference between eosinophilic CCRCC and other eosinophilic tumors (P<0.05). While basolateral staining was observed in papillary tumors, membrane staining was observed in other stained cases. It was hypothesized that the use of TRPM4 along with morphological findings, cytokeratin 7 and other markers may be useful for the differentiation of eosinophilic kidney tumors.Publication Metadata only Benign prostat hiperplazisinin cerrahi tedavisi sonrası tanı konulan insidental prostat kanseri(2021-10-01T00:00:00Z) İlktaç, Abdullah; Ersöz, Cevper; Doğan, Bayram; Akçay, Muzaffer; Yıldız, Pelin; Çoban, Ganime; Akbulut, Habib; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; DOĞAN, BAYRAM; AKÇAY, MUZAFFER; YILDIZ, PELİN; ÇOBAN, GANİME; AKBULUT, HABİB