Person: ÇAKIR, FATMA BETÜL
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Publication Metadata only Central Nervous System Metastases in Neuroblastoma: Results of Turkish Pediatric Oncology Group Neuroblastoma 2009 (TPOG-NB-2009) Protocol(2018-11-01) Cecen, E.; Ince, D.; Sevinir, B.; Cakir, FATMA BETÜL; KURUCU, NİLGÜN; GÜLER, ELİF; VURAL, S.; KOKSAL, Y.; ONIZ, H.; Oguz, A.; Sarialioglu, F.; Olgun, N.; ÇAKIR, FATMA BETÜLPublication Metadata only False Positivity of Gallium-68 Dota-Octreotid PET/MR Secondary to cis-Retinoic Asid Treatment in a Patient with Neuroblastoma(2018-11-01T00:00:00Z) Cakir, FATMA BETÜL; Besli, L. Uslu; KIRAN, Tuğçe; ÇAKIR, FATMA BETÜL; KIRAN, TUĞÇEPublication Metadata only Nimotuzumab-containing regimen for pediatric diffuse intrinsic pontine gliomas: a retrospective multicenter study and review of the literature.(2019-01-01T00:00:00Z) Kebudi, R; Cakir, FATMA BETÜL; Bay, SB; Gorgun, O; Altınok, P; Iribas, A; Agaoglu, FY; Darendeliler, E; ÇAKIR, FATMA BETÜLPublication Open Access Ceftriaxone-induced hemolytic anemia in a child successfully managed with intravenous immunoglobulin(2016-03-01) Vehapoglu, AYSEL; GOKNAR, Nilufer; TUNA, Rumeysa; Cakir, FATMA BETÜL; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIR, FATMA BETÜLDrug-induced hemolytic anemia is an immune-mediated phenomenon that leads to the destruction of red blood cells. Here, we present a case of life-threatening ceftriaxone-induced hemolytic anemia (CIHA) in a previously healthy 3-year-old girl. We also reviewed the literature to summarize the clinical features and treatment of hemolytic anemia. Acute hemolysis is a rare side effect of ceftriaxone therapy associated with high mortality. Our patient had a sudden loss of consciousness with macroscopic hematuria and her hemoglobin dropped from 10.2 to 2.2 g/dl over 4 hours, indicating that the patient had life-threatening hemolysis after an intravascular dose of ceftriaxone who had previously been treated with ceftriaxone in intramuscular form for six days. CIHA is associated with a positive direct antiglobulin test, revealing the presence of IgG in all cases and C3d in most cases. Our patient's direct antiglobulin test was positive for IgG (3+) and for C3d (4+). The case was managed successfully with supportive measures and intravenous immunoglobulin therapy. Ceftriaxone is used very frequently in children; an early diagnosis and proper treatment of hemolytic anemia are essential to improve the patient outcome. The pathophysiological mechanism is the same as for non-drug autoimmune hemolytic anemia. However, there is still no consensus treatment for CIHA. Intravenous immunoglobulin can be used in clinical emergencies, such as our case, or in refractory cases.Publication Metadata only Prediction of outcome in pediatric Hodgkin lymphoma based on interpretation of <sup>18</sup>FDG-PET/CT according to ΔSUV<sub>max</sub>, Deauville 5-point scale and IHP criteria.(2017-11-01) ISIK, EG; KUYUMCU, S; KEBUDI, R; SANLI, Y; KARAKAS, Z; Cakir, FATMA BETÜL; UNAL, SN; ÇAKIR, FATMA BETÜLPublication Metadata only Primary Osteosarcoma of the Rib: Distribution of Sex.(2018-08-01) Büyükkapu, Bay; KEBUDI, R; Cakir, FATMA BETÜL; ÇAKIR, FATMA BETÜLPublication Metadata only Testis Involvement in Neuroblastoma: Report of 3 Cases in the Turkish Pediatric Oncology Group-Neuroblastoma Study and Review of the Literature.(2019-01-01T00:00:00Z) Kebudi, R; Koc, BS; Akici, F; Cakir, FATMA BETÜL; Gorgun, O; Olgun, N; ÇAKIR, FATMA BETÜL