Person: HEKİMOĞLU, EMİNE RÜMEYSA
Search Results
Prefabricated Osteocutaneous Neural Island Flap Model
2011-11-01, Sonmez, Erhan, Ocal, Engin, Konas, Ersoy, Hekimoglu, Rumeysa, KORKUSUZ, PETEK, Dadaci, Mehmet, Safak, Tunc, HEKİMOĞLU, EMİNE RÜMEYSA
Neural-based flaps are an interesting clinical choice particularly in difficult cases that may not be reconstructed with known techniques. Their popularity is gradually increasing because these flaps offer the advantage of preservation of major extremity arteries and avoidance of microsurgical techniques. Our aim was to explore the feasibility of prefabrication of an osteocutaneous neural island flap model in this study. A peripheral nerve of the rat was implanted into the subcutaneous tissue of a skin flap that was connected to a segment of bone by a soft-tissue bridge, to prefabricate an osteocutaneous flap that was supplied only by the intrinsic vasculature of that nerve after a preliminary delay period. At the end of this study, based on direct observation, microangiographic findings, and additionally, a detailed histologic analysis consisting of both qualitative and quantitative assessments, we have proved that it was possible to prefabricate an osteocutaneous composite flap based on the vascularity of a peripheral nerve after a 2-step delay period. We believe that the clinical application of this new flap will gradually develop based on further experimental studies.
Effects of nitrite on hepatic ischemia-reperfusion injury
2012-01-01, Ciftci, Samiye Yabanoglu, Yalovac, Acelya, Hekimoglu, Rumeysa, Gumusel, Bulent, KORKUSUZ, PETEK, UÇAR, GÜLBERK, HEKİMOĞLU, EMİNE RÜMEYSA
Aim: Hepatic ischemia-reperfusion (IR) injury is a major complication associated with liver transplantation and surgery. The aim of this study is to investigate the cytoprotective effects of nitrite on hepatic IR injury.
Local Ocular Surface Alterations in Children with Hashimoto-s Thyroiditis
2019-08-17, Kiziltoprak, Hasan, Koc, Mustafa, Tekin, Kemal, Hekimoglu, Rumeysa, Inanc, Merve, Yilmaz, Aslihan Arasli, Elmaogullari, Selin, Aycan, Zehra, HEKİMOĞLU, EMİNE RÜMEYSA
Purpose: To evaluate the ocular surface characteristics based on Schirmer-s test, tear break-up time (TBUT), and conjunctival impression cytology (CIC) in children with Hashimoto-s thyroiditis (HT). Methods: This study included 51 children with HT and 53 control subjects. The ocular surface characteristics of participants were assessed via Schirmer-s test, TBUT, and CIC. Conjunctival samples were examined cytologically according to the Nelson grading system. Results: Schirmer-s and TBUT results were significantly lower in HT group (p < .05). All samples in both the study and control groups were evaluated as grade 0 according to the Nelson classification (p = .841), however, goblet cell density (GCD) was significantly lower in HT group (p = .001). Schirmer test results were significantly associated with the duration of HT (p = .025, r = -0.311). Conclusion: Hashimoto-s thyroiditis without any ocular complaints may cause ocular surface changes with TBUT and Schirmer-s. Although CIC analysis showed similar grading results, GCD was significantly decreased in HT group.
Angiotensin-Converting Enzyme Inhibitor Enalapril Reduces Formation of Hypertrophic Scars in a Rabbit Ear Wounding Model
2013-09-01, UZUN, HAKAN, Bitik, Ozan, Hekimoglu, Rumeysa, Atilla, Pergin, Kayikcioglu, Aycan Ugur, HEKİMOĞLU, EMİNE RÜMEYSA
Background: Angiotensin-converting enzyme inhibitors are widely used in medicine because of their antihypertensive and antifibrogenic effects. Angiotensin-converting enzyme activates angiotensin I to angiotensin II, which plays an important regulatory role in wound healing and collagen production. The authors investigated whether systemic administration of angiotensin-converting enzyme inhibitors has any effect on formation of hypertrophic scars using the rabbit ear wound model.
Alterations of Tear Film and Ocular Surface in Children with Type 1 Diabetes Mellitus
2019-01-01, Inanc, Merve, Kiziltoprak, Hasan, Hekimoglu, Rumeysa, Tekin, Kemal, Ozalkak, Servan, Koc, Mustafa, Bayramoglu, Elvan, ZIRH, SELİM, Yuruker, Sinan, Aycan, Zehra, HEKİMOĞLU, EMİNE RÜMEYSA