Person: HEKİMOĞLU, EMİNE RÜMEYSA
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Histopathological Analysis of Internal Limiting Membrane Surgically Peeled From Eyes with Epiretinal Membrane
Investigation of Neuroinflammation and Neuroprotective effects of 6paradol in amyloid beta infused Alzheimer-s Disease rat model
Comparison of Ocular Surface Alterations Following Laser Assisted in Situ Keratomileusis and Photorefractive Keratectomy
HISTOLOGICAL FINDINGS OF HETEROTOPIC AUTOTRANSPLANTATİON OF THE ADRENAL GLAND IN RATS PERFORMED BY BILATERAL ADRENALECTOMY
Extremely High Anti-Mullerian Hormone Levels Detected During Infertility Work-up Revealing Sex Cord Tumor with Annular Tubules and Underlying Peutz-Jeghers Syndrome
A low direct electrical signal attenuates oxidative stress and inflammation in septic rats
Electrical stimulation is proposed to exert an antimicrobial effect according to studies performed using bacterial and cell cultures. Therefore, we investigated the effects of electrification on inflammation in septic rats. Twenty-eight male Wistar albino rats were divided into 4 groups: healthy control (C), electrified healthy (E), sepsis (S), and electrified sepsis (SE) groups. Staphylococcus aureus (1 x 109 colonies) in 1 ml of medium was intraperitoneally injected into rats to produce a sepsis model. The rats in the E and SE groups were exposed to a low direct electrical signal (300 Hz and 2.5 volts) for 40 min and 1 and 6 h after bacterial infection. Immediately after the second electrical signal application, blood and tissue samples of the heart, lung, and liver were collected. An antibacterial effect of a low direct electrical signal was observed in the blood of rats. The effects of electrical signals on ameliorating changes in the histological structure of tissues, blood pH, gases, viscosity and cell count, activities of some important enzymes, oxidative stress parameters, inflammation and tissue apoptosis were observed in the SE group compared to the S group. Low direct electrical signal application exerts antibacterial, antioxidant, anti-inflammatory and antiapoptotic effects on septic rats due to the induction of electrolysis in body fluids without producing any tissue damage.