Person: HEKİMOĞLU, EMİNE RÜMEYSA
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Publication Metadata only Fetal Cell Microchimerism; Normal and Immunocompromised Gestations in Mice(2019-01-01) Beksac, M. Sinan; Fadiloglu, Erdem; Cakar, Ayse Nur; Gurbuz, Rumeysa Hekimoglu; Atilla, Pergin; Onbasilar, Ilyas; Beksac, Kemal; Katlan, Doruk Cevdi; Mumusoglu, Sezcan; Calis, Pinar; Beksac, Meral; HEKİMOĞLU, EMİNE RÜMEYSAPublication Metadata only Impaired Placentation and Early Pregnancy Loss in Patients with MTHFR Polymorphisms and Type-1 Diabetes Mellitus(2019-01-01) Gurbuz, Rumeysa Hekimoglu; ATİLLA, PERGİN; Orgul, Gokcen; TANAÇAN, ATAKAN; Dolgun, Anil; Cakar, Ayse Nur; BEKSAÇ, MEHMET SİNAN; HEKİMOĞLU, EMİNE RÜMEYSAPublication Metadata only Histopathological Analysis of Internal Limiting Membrane Surgically Peeled From Eyes with Epiretinal Membrane(2016-02-01) Beyazyildiz, Özlem; Tirhiş, Mehmet Hakan; Hekimoğlu, Emine Rümeysa; Beyazyildiz, Emrullah; Kaymaz, Figen; Yilmazbaş, Pelin; Öztürk, Faruk; HEKİMOĞLU, EMİNE RÜMEYSAPublication Metadata only Differential expression of leukemia inhibitory factor and insulin like growth factor-1 between normal pregnancies, partial hydatidiform moles and complete hydatidiform moles(2018-09-01) Yucel Cicek, Ozge Senem; Hekimoglu, Emine Rümeysa; Turgal, Mert; ATİLLA, PERGİN; Cakar, Ayse Nur; USUBÜTÜN, ALP; BEKSAÇ, MEHMET SİNAN; HEKİMOĞLU, EMİNE RÜMEYSAPublication Metadata only Prefabricated Osteocutaneous Neural Island Flap Model(2011-11-01) Sonmez, Erhan; Ocal, Engin; Konas, Ersoy; Hekimoglu, Rumeysa; KORKUSUZ, PETEK; Dadaci, Mehmet; Safak, Tunc; HEKİMOĞLU, EMİNE RÜMEYSANeural-based flaps are an interesting clinical choice particularly in difficult cases that may not be reconstructed with known techniques. Their popularity is gradually increasing because these flaps offer the advantage of preservation of major extremity arteries and avoidance of microsurgical techniques. Our aim was to explore the feasibility of prefabrication of an osteocutaneous neural island flap model in this study. A peripheral nerve of the rat was implanted into the subcutaneous tissue of a skin flap that was connected to a segment of bone by a soft-tissue bridge, to prefabricate an osteocutaneous flap that was supplied only by the intrinsic vasculature of that nerve after a preliminary delay period. At the end of this study, based on direct observation, microangiographic findings, and additionally, a detailed histologic analysis consisting of both qualitative and quantitative assessments, we have proved that it was possible to prefabricate an osteocutaneous composite flap based on the vascularity of a peripheral nerve after a 2-step delay period. We believe that the clinical application of this new flap will gradually develop based on further experimental studies.Publication Metadata only Trimetazidine has protective effects on spermatogenesis in a streptozotocin-induced diabetic rat model(2017-12-01) Ozcan, M.F.; Hekimoglu, Emine Rümeysa; Ener, K.; Namuslu, M.; Altintas, R.; Celik, H.T.; Akbulut, Z.; Altinova, S.; HEKİMOĞLU, EMİNE RÜMEYSAPublication Metadata only Local Ocular Surface Alterations in Children with Hashimoto-s Thyroiditis(2019-08-17) Kiziltoprak, Hasan; Koc, Mustafa; Tekin, Kemal; Hekimoglu, Rumeysa; Inanc, Merve; Yilmaz, Aslihan Arasli; Elmaogullari, Selin; Aycan, Zehra; HEKİMOĞLU, EMİNE RÜMEYSAPurpose: To evaluate the ocular surface characteristics based on Schirmer-s test, tear break-up time (TBUT), and conjunctival impression cytology (CIC) in children with Hashimoto-s thyroiditis (HT). Methods: This study included 51 children with HT and 53 control subjects. The ocular surface characteristics of participants were assessed via Schirmer-s test, TBUT, and CIC. Conjunctival samples were examined cytologically according to the Nelson grading system. Results: Schirmer-s and TBUT results were significantly lower in HT group (p < .05). All samples in both the study and control groups were evaluated as grade 0 according to the Nelson classification (p = .841), however, goblet cell density (GCD) was significantly lower in HT group (p = .001). Schirmer test results were significantly associated with the duration of HT (p = .025, r = -0.311). Conclusion: Hashimoto-s thyroiditis without any ocular complaints may cause ocular surface changes with TBUT and Schirmer-s. Although CIC analysis showed similar grading results, GCD was significantly decreased in HT group.Publication Metadata only Alterations of Tear Film and Ocular Surface in Children with Type 1 Diabetes Mellitus(2019-01-01) Inanc, Merve; Kiziltoprak, Hasan; Hekimoglu, Rumeysa; Tekin, Kemal; Ozalkak, Servan; Koc, Mustafa; Bayramoglu, Elvan; ZIRH, SELİM; Yuruker, Sinan; Aycan, Zehra; HEKİMOĞLU, EMİNE RÜMEYSAPublication Metadata only Effects of nitrite on hepatic ischemia-reperfusion injury(2012-01-01) Ciftci, Samiye Yabanoglu; Yalovac, Acelya; Hekimoglu, Rumeysa; Gumusel, Bulent; KORKUSUZ, PETEK; UÇAR, GÜLBERK; HEKİMOĞLU, EMİNE RÜMEYSAAim: Hepatic ischemia-reperfusion (IR) injury is a major complication associated with liver transplantation and surgery. The aim of this study is to investigate the cytoprotective effects of nitrite on hepatic IR injury.Publication Metadata only Angiotensin-Converting Enzyme Inhibitor Enalapril Reduces Formation of Hypertrophic Scars in a Rabbit Ear Wounding Model(2013-09-01) UZUN, HAKAN; Bitik, Ozan; Hekimoglu, Rumeysa; Atilla, Pergin; Kayikcioglu, Aycan Ugur; HEKİMOĞLU, EMİNE RÜMEYSABackground: Angiotensin-converting enzyme inhibitors are widely used in medicine because of their antihypertensive and antifibrogenic effects. Angiotensin-converting enzyme activates angiotensin I to angiotensin II, which plays an important regulatory role in wound healing and collagen production. The authors investigated whether systemic administration of angiotensin-converting enzyme inhibitors has any effect on formation of hypertrophic scars using the rabbit ear wound model.