Person: ŞENGÜL, YILDIZHAN
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Publication Metadata only Comparison of optic coherence tomography results in patients with diagnosed epilepsy: Findings in favor of neurodegeneration(2019-03-01T00:00:00Z) TAK, ALİ ZEYNAL ABİDİN; ŞENGÜL, YILDIZHAN; Ekmekci, Burcu; KARADAĞ, AYŞE SEVGİ; ŞENGÜL, YILDIZHANBackground: Epilepsy is a chronic neurological disease characterized with recurrent seizures. Progressive neuronal degeneration is a common consequence of long-term and/or recurrent seizure activity in epilepsy. Optical coherence tomography (OCT) is a new medical imaging technique that displays biological tissue layers as high-resolution tomographic sections. The aim of our study was to evaluate OCT findings in patients with epilepsy and to compare OCT findings in terms of disease duration, presence of status, seizure frequency, and drug use.Publication Open Access EVALUATION OF NEUTROPHIL-TO-LYMPHOCYTE RATIO AND PLATELET-TO-LYMPHOCYTE RATIO IN ESSENTIAL TREMOR IS THERE SYSTEMIC INFLAMMATION IN ESSENTIAL TREMOR?(2019-01-01T00:00:00Z) TAK, ALİ ZEYNAL ABİDİN; ŞENGÜL, YILDIZHAN; ŞENGÜL, YILDIZHANIntroduction - Although essential tremor (ET) is the most common cause of tremor, the pathology and underlying mechanisms have not fully understood yet. In addition to kinetic tremor, patients may present several types of tremor, gait ataxia, hearing deficits and eye movement abnormalities. Non-motor symptoms and signs have also added to definition of ET. There is significant evidence indicating the neurodegenerative nature of the disease. New studies indicate that inflammation may have a place in the etiology. The neutrophil-to lymphocyte ratio (NLR) and the platelet-to lymphocyte ratio (PLR) have recently begun to be used as a marker of systemic inflammation. Our study aims at finding a clue for systemic inflammation in ET.Publication Metadata only Inflammation with Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Restless Legs Syndrome(2019-01-01T00:00:00Z) TAK, ALİ ZEYNAL ABİDİN; ŞENGÜL, YILDIZHAN; ŞENGÜL, YILDIZHANPublication Open Access Investigation and Clinical Importance of Obsessive and Compulsive Signs Among Patients with Restless Legs Syndrome(2019-07-01T00:00:00Z) ŞENGÜL, YILDIZHAN; YILMAZ, Onur; Sengul, Hakan Serdar; PARLAKKAYA, FATMA BÜŞRA; ÖZTÜRK, AHMET; ŞENGÜL, YILDIZHAN; YILMAZ, ONUR; PARLAKKAYA, FATMA BÜŞRA; ÖZTÜRK, AHMETObjective: The purpose of this study was to examine obsessive and compulsive signs among patients with Restless Legs syndrome (RLS), to compare the results with healthy controls and to investigate clinic importance of those signs. Methods: Thirty nine patients with RLS and 40 age-, sex- and education- matched healthy controls were assessed in Bezmialem Foundation University Medical Faculty Hospital Neurology and Psychiatry Clinics Hospital. Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-IV axis-1 disorders severe combined immune deficiency-1, socio-demographic data form and Maudsley obsessive compulsive inventory (MOCI) were applied to both patients and controls. Patient group seas also classified according to the International RLS study group RLS severity scale. Results: Patient group had higher MOCI total scores and doubting and rumination subscale scores than the control group and the difference was statistically significant (p<0.05). No statistically significant relationship was found between RLS severity score and MOCI total and subscale scores. Conclusion: Patients with RLS were generally found to have more obsessive and compulsive signs than healthy controls. In view of the fact that RLS is often a late-diagnosed syndrome, searching for concomitant RLS among young people who have obsessive and compulsive signs may be helpful for early diagnosis of RLS.