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YARDIMCI, ERKAN

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ERKAN
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YARDIMCI
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2014 - 20198
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Start date: 2012 × End date: 2019 × Author: MALYA, FATMA ÜMİT ×

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Now showing 1 - 8 of 8
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    Elektif Kolorektal Kanser Cerrahisinde Laparoskopiden Açık Ameliyata Geçişi Etkileyen Faktörler: Bezmialem Genel Cerrahi Deneyimi.
    (2014-04-20) ÇİPE, GÖKHAN; YARDIMCI, ERKAN; MEMMİ, NAİM; AKÇAKAYA, ADEM; YARDIMCI, ERKAN; MALYA, FATMA ÜMİT; MEMMİ, NAİM; AKÇAKAYA, ADEM
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    PublicationOpen Access
    Comparison of Weight Loss, Ghrelin, and Leptin Hormones After Ligation of Left Gastric Artery and Sleeve Gastrectomy in a Rat Model.
    (2017-03-24) YARDIMCI, ERKAN; BOZKURT, SÜLEYMAN; CENGIZ, MB; Malya, FATMA ÜMİT; YARDIMCI, ERKAN; BOZKURT, SÜLEYMAN; MALYA, FATMA ÜMİT
    BACKGROUND Ligation of the left gastric artery (LLGA), which supplies the fundus of the stomach, may reduce the appetite hormone ghrelin, resulting in weight control. The aim of this study was to compare LLGA and sleeve gastrectomy (SG) in terms of postoperative outcomes in a rat model. MATERIAL AND METHODS Fifteen male Wistar albino rats, weighing >350 grams (range 350-525 grams), were enrolled in LLGA (N=5), SG (N=5), and control (N=5) groups. Blood samples were drawn preoperatively and also during the first and fourth week postoperatively to assay ghrelin and leptin hormone levels. Body weight was measured in each group. RESULTS The maximum reduction in ghrelin level (41.5%) was found in the LLGA group. Considerable% total weight loss (TWL) (mean 24.1%) was observed in the SG group, and slight%TWL was noted in the control and LLGA groups (means of 0.1% and 2.1%, respectively). There was no significant difference in mean percent weight change between the LLGA and the SG groups (p=0.08). Blood sample analysis revealed no statistically significant changes in ghrelin or leptin levels between the groups (p=0.9 and p=0.3, respectively). CONCLUSIONS We present evidence that LLGA causes the same reduction in ghrelin hormone levels as SG at 4 weeks after surgery in a rat model. However, LLGA did not cause the same%TWL as SG. The mechanism of weight loss in SG is most likely due to restriction and to the effects of the procedure, rather than due to neurohormonal changes.
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    PublicationOpen Access
    Nonclosure of the Peritoneum during Appendectomy May Cause Less Postoperative Pain: A Randomized, Double-Blind Study
    (2019-01-01) BEKTAŞOĞLU, HÜSEYİN KAZIM; Hasbahceci, Mustafa; YIĞMAN, SAMET; YARDIMCI, ERKAN; KUNDUZ, ENVER; MALYA, FATMA ÜMİT; BEKTAŞOĞLU, HÜSEYİN KAZIM; YIĞMAN, SAMET; YARDIMCI, ERKAN; KUNDUZ, ENVER; MALYA, FATMA ÜMİT
    Objective: We aim to evaluate the effect of peritoneal closure on postoperative pain and life quality associated with open appendectomy operations. Methods: This is a single-center, prospective, randomized, and double-blinded study. Here, 18-65-year-old patients who underwent open appendectomy for acute appendicitis were included. Demographic data of the patients, operation time, length of hospital stay, pain scores using a 10 cm visual analogue scale (VAS) on the first postoperative day, quality of life assessment using the EuroQol-5D-5L questionnaire on postoperative 10th day, deep wound dehiscence, bowel obstruction, and mortality data were recorded. Results: In total, 112 patients were included in the study. The demographic data showed no significant difference between the groups. The median VAS score was lower in the group with open peritoneum, but this difference was not statistically significant (3 vs. 4, p=0.134). The duration of surgery was significantly shorter in the peritoneal nonclosure group (31.0 ± 15.1 vs. 38.5 ± 17.5 minutes, p=0.016). Overall complication rates and life quality test (EuroQol-5D-5L) results were similar between groups. Conclusion: Nonclosure of the peritoneum seems to shorten the duration of surgery without increasing complications during open appendectomy. Postoperative pain and life quality measures were not affected by nonclosure of the peritoneum. This trial is registered with NCT02803463.
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    The Effects of Preoperative Endoscopic Tattooing on Distal Surgical Margin and Ileostomy Rates in Laparoscopic Rectal Cancer Surgery: A Prospective Randomized Study.
    (2016-08-01) CIPE, G; CENGIZ, MB; IDIZ, UO; YARDIMCI, ERKAN; Malya, U; FIRAT, D; MUSLUMANOGLU, M; YARDIMCI, ERKAN; MALYA, FATMA ÜMİT
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    PublicationOpen Access
    Intraoperative palpation of sentinel lymph nodes can accurately predict axilla in early breast cancer
    (2019-01-01) Ozkurt, Enver; Yardimci, ERKAN; Tukenmez, Mustafa; Ersoy, YELİZ EMİNE; Yilmaz, Ravza; Cabioglu, Neslihan; Karanlik, Hasan; Kulle, Cemil Burak; Malya, FATMA ÜMİT; Onder, Semen; Gucin, ZÜHAL; Igci, Abdullah; Ozmen, Vahit; Dinccag, Ahmet Sait; Muslumanoglu, Mahmut; YARDIMCI, ERKAN; ERSOY, YELIZ EMINE; MALYA, FATMA ÜMİT; GÜCİN, ZÜHAL
    Recent randomized trials have shown that completion axillary lymph node dissection (ALND) is not required in all patients with a positive sentinel lymph node (SLN) who will receive radiation therapy. Although routine intraoperative pathologic assessment (IPA) becomes unnecessary and less indicated by breast surgeons in the United States and some European countries, it is still widely used all around the world. In this prospective study, the feasibility of intraoperative nodal palpation (INP) as opposed to IPA of the SLN has been analyzed. Between March 2014 and June 2015, 305 patients with clinical T1-2/N0 breast cancer from two different breast clinics (cohort A; [n = 225] and cohort B; [n = 80]) who underwent any breast surgery with sentinel lymph node biopsy (SLNB) were included in this study. Surgeons evaluated the SLNs by manual palpation before sending for IPA, and findings compared with the final pathology. The positive predictive values (PPV) of INP and IPA were 81.8% and 97.9%, respectively, whereas the negative predictive values (NPV) of INP and IPA were 83% and 92.4%. The accuracies of INP and IPA were 82.6% and 94.1%, respectively. If patients with SLNB including micrometastasis were also considered in the final pathologic assessment (FPA) (-) group that would not require a further axillary dissection, the revised NPV of INP and FPA were found to be 92.6% and 98.1%, respectively. The revised accuracy of INP also found to be increase to 86.9%. Our study, which is the only prospective one about palpation of dissected SLNs in the literature, suggests that INP can help to identify patients who do not need ALND, which encourages omitting IPA in cT1-2 N0 breast cancer.
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    Pankreatikoduodenektomiden laparoskopik pankreatikoduadenektomiye geçişte karşılaşılan zorluklar
    (2014-04-20) KARATEPE, OĞUZHAN; MALYA, FATMA ÜMİT; HASBAHCECI, MUSTAFA; YARDIMCI, ERKAN; AKBULUT, HÜSEYİN; ÇİPE, GÖKHAN; ÇİTGEZ, BÜLENT; AKÇAKAYA, ADEM; MÜSLÜMANOĞLU, MAHMUT; MALYA, FATMA ÜMİT; YARDIMCI, ERKAN; AKBULUT, HÜSEYİN; AKÇAKAYA, ADEM
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    Bariatrik cerrahide Bezmialem deneyimi
    (2015-04-26) TAŞCI, YUNUS; BOZKURT, SÜLEYMAN; COŞKUN, HALİL; YARDIMCI, ERKAN; MALYA, FATMA ÜMİT; HASBAHCECI, MUSTAFA; ERSOY, YELİZ EMİNE; AKÇAKAYA, ADEM; BOZKURT, SÜLEYMAN; COŞKUN, HALIL; YARDIMCI, ERKAN; KUNDUZ, ENVER; MALYA, FATMA ÜMİT; ERSOY, YELIZ EMINE; AKÇAKAYA, ADEM
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    Pankreas başı tümörlerinde preoperatif tam kaplı metal stent ile plastik bilier stentin pankreatikoduadenektomi operasyonu üzerine etkileri
    (2014-04-20) KARATEPE, OĞUZHAN; HASBAHCECI, MUSTAFA; CENGİZ, MERVE BÜŞRA; AKBULUT, HÜSEYİN; YARDIMCI, ERKAN; AKÇAKAYA, ADEM; MÜSLÜMANOĞLU, MAHMUT; MALYA, FATMA ÜMİT; BEKTAŞOĞLU, HÜSEYİN KAZIM; AKBULUT, HÜSEYİN; YARDIMCI, ERKAN; AKÇAKAYA, ADEM; ŞENTÜRK, HAKAN