Person: İNAN, BEKİR
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Publication Metadata only The Effects of Levosimendan Exposure on Oxidant/Antioxidant Status and Trace Element Levels in the Pulmonary Artery of Rats(2013-06-01T00:00:00Z) AY, YASİN; AYDIN, CEMALETTİN; Basel, Halil; Bektaş, Hava; Bulut, Gulay; İNAN, BEKİR; Ay, NURAY; Demir, Ismail; AY, YASİN; AYDIN, CEMALETTİN; İNAN, BEKİR; KAHRAMAN AY, NURAYWe investigated both the effect of levosimendan and the role of oxidant/antioxidant status and trace element levels in the pulmonary artery of rats. Fourteen male Wistar albino rats were randomly divided into two groups of seven animals each. Group 1 was not exposed to levosimendan and served as a control. Levosimendan (12 mu g/kg) diluted in 10 ml 0.9 % NaCl was administered intraperitoneally to group 2. Animals of both groups were killed after 3 days, and their pulmonary arteries were harvested to determine changes in tissue oxidant/antioxidant status and trace element levels. The animals in both groups were killed 72 h after the levosimendan exposure treatment, and pulmonary arteries were harvested to determine levels of the lipid peroxidation product MDA and the antioxidant GSH as well as the decreased activity of antioxidant enzymes such as SOD, GSH-Px and CAT. It was found that MDA levels increased in pulmonary artery tissues of rats after levosimendan administration. The GSH level decreased in the pulmonary artery of rats after levosimendan treatment. Co, Mn, Fe, Cd and Pb levels were significantly higher (P < 0.001) and Mg, Zn and Cu levels significantly lower (P < 0.001) in the levosimendan group compared to the control group. These results suggest that levosimendan treatment caused an increase in free radical production and a decrease in antioxidant enzyme activity in the pulmonary artery of levosimendan-treated rats. It also caused a decrease or increase in the levels of many minerals in the pulmonary artery, which is an undesirable condition for normal pharmacological function.Publication Metadata only The Last Option Before the Prosthetic Graft in Arteriovenous Fistula Formation: Brachiobasilic Vein Transposition(2011-04-01T00:00:00Z) İNAN, BEKİR; Aydin, Unal; Basel, Halil; Erkalp, Kerem; Yasar, Tahsin; Keskin, Sıddık; İNAN, BEKİRObjective: Simple arteriovenous fistulas created with cephalic vein provide good vascular access for hemodialysis. Brachiobasilic vein transposition (BBVT) and prosthetic graft (PG) are two alternative methods for vascular access if cephalic vein occlusion have occured. In this study we aimed to compared these two methods and determine the advantages of the procedure. Material and Methods: From June 2006 to April 2009, 83 patients who had undergone BBVT and PG procedures were analyzed retrospectively. The cases were evaluated with their follow up data of 24 months. Trombosis, patency, infection, revision and infection rates were determined with Chi Square and Fischer-s Exact tests. Results: No significiant difference was determined between the groups for demographic data and risk factors. However, trombosis (p=0.021), patency (p=0.040), infection (p=0.001) and revision (p=0.001) rates of BBVT group were superior to PG group. Mortality was similar in both groups (p=0.46). Conclusion: BBVT procedure with high patency and low infection rate is an efficient, safe and preferred method for vascular access.Publication Metadata only Ischaemic mitral regurgitation: The effects of ring annuloplasty and suture annuloplasty repair techniques on left ventricular re-remodeling(2013-01-01T00:00:00Z) AYDIN, CEMALETTİN; Kara, Ibrahim; AY, YASİN; İNAN, BEKİR; Basel, Halil; Yanartas, Mehmet; ZEYBEK, RAHMİ; AYDIN, CEMALETTİN; AY, YASİN; İNAN, BEKİR; ZEYBEK, RAHMİObjective: To examine the mid-term results of patients on whom a coronary revascularization as well as a mitral ring and suture annuloplasty have been performed due to coronary artery disease (CAD) and ischaemic mitral regurgitation (IMR).Publication Metadata only Surgical approach for the treatment of inferior vena cava injuries(2011-07-01T00:00:00Z) İNAN, BEKİR; Aydin, Unal; Erkalp, Kerem; Yasar, Tahsin; Basel, Halil; İNAN, BEKİRBackground: In this study, surgical treatments performed by using autologous materials and other methods along with their results of these treatments were investigated.Publication Open Access Comparison of the Health Related Quality of Life of Patients Following Mitral Valve Surgical Procedures in the 6-Months Follow-up: A Prospective Study(2013-04-01T00:00:00Z) AY, YASİN; KARA, İBRAHİM; AYDIN, CEMALETTİN; KAHRAMAN AY, Nuray; İNAN, BEKİR; Basel, Halil; ZEYBEK, RAHMİ; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY; İNAN, BEKİR; ZEYBEK, RAHMİPurpose: The aim of the present study is to evaluate the health-related quality of life of the patients who underwent mitral valve repair (MvRp) and mitral valve replacement (MVR).