Person: AKBULUT, HABİB
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Publication Systematic versus cognitive targeted biopsy: evaluation of parameters related to clinically significant prostate cancer and comparison of detection rates(2022-10-01) Ersöz C.; İlktaç A.; Kalkan S.; Kayalı Y.; Akbulut H.; Toprak H.; Doğan B.; ERSÖZ, CEVPER; İLKTAÇ, ABDULLAH; KALKAN, SENAD; AKBULUT, HABİB; TOPRAK, HÜSEYİN; DOĞAN, BAYRAMPublication The Success of Pyeloplasty in Adult Patients with Ureteropelvic Junction Obstruction(2022-12-01) İLKTAÇ A.; ERSÖZ C.; DOĞAN B.; AKBULUT H.; İLBEY Y. Ö.; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; DOĞAN, BAYRAM; AKBULUT, HABİB; İLBEY, YUSUF ÖZLEMPublication The effect of post-treatment PSA change and multiparametric prostate MRI findings in the detection of prostate cancer in patients receiving antibiotics due to PSA elevation(2020-07-24T00:00:00Z) Kayalı, Yunus; Doğan, Bayram; İlktaç, Abdullah; Ersöz, Cevper; Akçay, Muzaffer; Gevher, Fatih; Akbulut, Habib; Balbay, Mevlana Derya; DOĞAN, BAYRAM; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; AKÇAY, MUZAFFER; GEVHER, FATİH; AKBULUT, HABİBPublication The relationship of neutrophil to lymphocyte ratio with testicular cancer(2020-01-01) İlktaç, Abdullah; Akbulut, Habib; Akçay, Muzaffer; Ersöz, Cevper; Doğan, Bayram; İLKTAÇ, ABDULLAH; DOĞAN, BAYRAM; ERSÖZ, CEVPER; AKÇAY, MUZAFFER; AKBULUT, HABİBPurpose: To assess the relationship between testicular germ cell tumors (TGCT) and neutrophil to lymphocyte ratio (NLR) and to determine whether this ratio can be used as a serum tumor marker. Material and Methods: Sixty-one patients with testicular germ cell tumors were included into the study. Patients were grouped as localized and non-localized. Histologically patients were categorized as seminoma and nonseminomatous germ cell tumors. Complete blood cell count was measured the day before surgery and at the postoperative 1st month. Preoperative and postoperative mean NLR values were compared. Results: Thirty-six patients (59%) had seminomas and 25 patients (41%) had nonseminomatous testicular cancer. Forty-fi ve patients (73.8%) had localized and 16 patients (26.2%) had non-localized testicular cancer. There was a statistically signifi cant difference between preoperative and postoperative mean NLR of the localized patients (p=0.001) but no such difference was detected for non-localized patients (p=0.576). Nineteen patients with localized seminomas had normal preoperative serum tumor markers. There was a signifi cant difference between preoperative and postoperative mean NLR in this group of patients (p=0.010). Twenty-six patients with localized tumors had preoperative increased serum tumor markers which normalized after orchiectomy. Mean NLR of these patients signifi cantly decreased from 3.10±2.13 to 1.62±0.59 postoperatively (p=0.010). Conclusions: NLR appears to be a useful marker for TGCT. It is successful in predicting localized and non-localized disease in early postoperative period.Publication Benign prostat hiperplazisinin cerrahi tedavisi sonrası tanı konulan insidental prostat kanseri(2021-10-01T00:00:00Z) İlktaç, Abdullah; Ersöz, Cevper; Doğan, Bayram; Akçay, Muzaffer; Yıldız, Pelin; Çoban, Ganime; Akbulut, Habib; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; DOĞAN, BAYRAM; AKÇAY, MUZAFFER; YILDIZ, PELİN; ÇOBAN, GANİME; AKBULUT, HABİBPublication Effects of Lipokit (R) Centrifugation on Morphology and Resident Cells of Adipose Tissue(2013-03-01T00:00:00Z) Duman, Selcuk; Aktan, Tahsin Murad; Cuce, Gokhan; Cihantimur, Bulent; Tokac, Mehmet; Akbulut, HABİB; AKBULUT, HABİBThe aim of adipose tissue engineering is creating autologus vascularized fat tissue to be used for practical soft tissue reconstruction in human clinic. Unfortunately, in practice, long-term results of fat transplantation are often untrustworthy and unreliable, to overcome this problem different many lipoinjection techniques developed in the last 20 years. Centrifuge is a fundamental step in the preparation of adipose tissue. We focused on some cell markers especially MSCs markers and histological structural properties after with lipokit centrifugation and without lipokit centrifugation of adipose tissue obtained by liposuction by this new technique. Adipose tissue was taken by liposuction and separates to two portions. One of them is centrifugated by Lipokit machine (C+) has a micro filter and the other is not (C-). After centrifugation smear slides and paraffin sections were prepared from these tissues. These slides were stained with H&E and Toluidine Blue. Paraffin sections were immunohistochemically stained with CD34, von Willebrand Factor, CD73, CD90 and CD105. Smear preparations showed a continuous three dimensional plasma membrane appearance of adipocytes. C+ and C-showed expression of CD34, von Willebrand Factor, CD73, CD90, CD105. C+ seems to have more free cells expressing than C-. While passing the filter of Lipokit, large adipocytes and connective tissue parts disintegrate and thus increases the surface area of lipoaspirate. Lipokit (R) machine release the group cells which are necessary for angiogenesis and they become more freely to construct angiogenesis.Publication Functional Genetic Variants in Apoptosis-associated FAS and FASL Genes and Risk of Bladder Cancer in a Turkish Population(2014-05-01T00:00:00Z) Verim, Levent; Timirci-Kahraman, Ozlem; AKBULUT, HABİB; AKBAŞ, ALPASLAN; Ozturk, Tulin; Turan, Saime; Yaylim, Ilhan; Ergen, Arzu; Ozturk, Oguz; Isbir, Turgay; AKBULUT, HABİBBackground: The present study aimed to evaluate the role of functional polymorphisms of apoptosis-associated Fatty acid synthase (FAS) and fatty acid synthase ligand (FASL) genes in bladder cancer susceptibility as first presentation in a Turkish population. Patients and Methods: Genotypes of 91 patients with bladder cancer and 101 healthy controls were evaluated for the polymorphism of FAS-1377 G/A and FASL-844 T/C genes by polymerase chain reaction and restriction fragment length polymorphism analysis. Results: The frequency of the FAS-1377 G allele was significantly higher in patients with bladder cancer compared to controls (p<0.001). A significantly increased risk for developing bladder cancer was found for the group bearing a T allele for FASL-844 compared to the homozygous FASL-844 CC genotype (p=0.027). FAS-1377 GG genotype and FASL-844 T allele were found to be independently associated with an increased risk of bladder cancer. Additionally, gene gene interaction analysis revealed that the frequency of FAS-1377AA with FASL-844TC was significantly lower in patients with bladder cancer in comparison to those of controls (p<0.001). Extensive studies for gene gene interaction are still needed. Conclusion: Our study provides new evidence that FAS-1377 G and FASL-844 T alleles may be used as low-penetrant risk factors for bladder cancer development in a Turkish population.Publication Mesane taşına bağlı penoskrotal lokalizasyonlu fatal nekrotizan fasiitis (Fournier gangreni)(2019-10-13T00:00:00Z) ŞALVARCI, AHMET; GÜRBÜZ, RECAİ; KAYALI, YUNUS; AKÇAY, MUZAFFER; AKBULUT, HABİB; DOĞAN, BAYRAM; Gevher, Fatih; İlktaç, Abdullah; KAYALI, YUNUS; AKÇAY, MUZAFFER; AKBULUT, HABİB; DOĞAN, BAYRAMPublication Ateşli silah yaralanması sonrası rekonstrikte peniste gelişen distal üretral striktürün fibrotik çevre doku ile eksizyonu ( Rekonstrikte penis, parsiyel penektomisi)(2019-10-13T00:00:00Z) GÜRBÜZ, RECAİ; ŞALVARCI, AHMET; KAYALI, YUNUS; AKÇAY, MUZAFFER; AKBULUT, HABİB; DOĞAN, BAYRAM; Gevher, Fatih; İlktaç, Abdullah; KAYALI, YUNUS; AKÇAY, MUZAFFER; AKBULUT, HABİB; DOĞAN, BAYRAMPublication Opuntica ficus indica’s anti-cancer and anti-inflammatory effect on prostate cancer cell line(2019-03-14T00:00:00Z) Erdoğdu, Ayşenur; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; AKBULUT, HABİB; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; AKBULUT, HABİB