2019-06-12T00:00:00Z, Kelahmetoğlu, Osman, Gürkan, Volkan, Güneren, Ethem, KELAHMETOĞLU, OSMAN, GÜRKAN, VOLKAN, GÜNEREN, ETHEM

2020-06-01T00:00:00Z, Mehdizade, Turan, Kelahmetoğlu, Osman, Gürkan, Volkan, Çetin, Güven, Güneren, Ethem, KELAHMETOĞLU, OSMAN, GÜRKAN, VOLKAN, ÇETİN, GÜVEN, GÜNEREN, ETHEM

Heparin-induced thrombocytopenia (HIT) is an underestimated complication of heparin treatment. Flap loss and related morbidity (even mortality) are caused by occlusion of the capillary vessels by a highly immunogenic complex formed by adherence of antiheparin antibodies to platelet factor 4. Early suspicion and effective treatment of HIT developing in two free flaps are described. We report on the management of two patients with HIT. Both patients were treated successfully by early suspicion and hematology consultation. Heparin products were discontinued; the patients were switched to a nonheparin anticoagulant. We emphasize the importance of early diagnosis, hematologist assessment, and a change to a nonheparin anticoagulant to prevent flap failure and possibly the catastrophic consequences of such failure.

2015-04-01, IMREN, Y., Gurkan, VOLKAN, Bilsel, K., DESTELI, E. E., Tuna, M., Gurcan, C., Tuncay, I., Sen, C., GÜRKAN, VOLKAN, BİLSEL, İSMAIL KEREM, TUNCAY, İBRAHİM

PURPOSE OF THE STUDY

2020-04-01T00:00:00Z, Abdallah, Anas, Sofuoglu, Ozden Erhan, Abdallah, Betul Guler, Emel, Erhan, Gunduz, Hasan Burak, Asilturk, Murad, GÜRKAN, VOLKAN

Objectives: This study aims to investigate the choke of graft or cement, the relationship between the graft types and union rates, functional results. and complications in hand and wrist benign bone lesions while also evaluating the diagnosis and treatment modalities of lesions with high recurrence potential like giant cell-containing lesions.

2022-11-01, DEMİRÖZ S., ÖKTEM F., Celik A., Erdogan O., ÖZKAN K., GÜRKAN V., GÜRKAN, VOLKAN

Introduction: There are several studies in the literature about pathological fractures but almost no in-formation about patients whose pathological fracture caused by a malignant lesion misdiagnosed and treated as a simple fracture. The aim of this study was to investigate patient and fracture characteristics, and outcomes in cases where fractures occurred in the presence of a malign pathology but were treated as simple fractures. Patients andMethods: Cases of malign bone lesions between 20 0 0 and 2020 were retrospectively re-viewed. Patients with a final diagnosis of malign bone lesion but whose pathological fractures were treated ignoring the underlying malign bone disease were included. Demographic, clinical and outcome data were collected from patient\"s medical records and analyzed.Results: Six patients met the inclusion criteria. Three of the patients were female and the cohort mean age was 56.8 +/- 21.8 years at the time of admission. Patient diagnoses were: renal cell carcinoma metas-tasis ( n = 1); colon cancer metastasis ( n = 1); chondrosarcoma ( n = 2); osteosarcoma ( n = 1); and undif-ferentiated pleomorphic sarcoma of bone ( n = 1). In all cases surgical management differed from those that should have been applied if the pathological fracture had been identified. Furthermore, surgical man-agement after definitive histological diagnosis were more aggressive compared to if the malignancy had been identified at first admission. All patients died after a mean follow-up of 16.67 +/- 11.7 months and the complication rate was 100%.Conclusion: When a pathological fracture is misdiagnosed and managed as a simple bone fracture, out-comes are extremely poor. In these situations, remedial surgery is more extensive, with increased com-plication rates and there is poor life expectancy.(c) 2022 Elsevier Ltd. All rights reserved.

2013-04-01, Bilsel, K., ERDIL, M., Elmadag, M., ERZINCANLI, A., Gurkan, VOLKAN, Tuncay, I., SEN, C., BİLSEL, İSMAIL KEREM, ELMADAĞ, NUH MEHMET, GÜRKAN, VOLKAN, TUNCAY, İBRAHİM

Aim. In this prospective randomized study with intraobserver and interobserver assessment, we aimed to compare the classifications and operative decisions of intertrochanteric fractures realized by orthopedic surgeons with standard radiographs and traction internal rotation radiographs by intraobserver and interobserver assessment.

2011-01-01, ORHUN, H, DURSUN, M, Gürkan, VOLKAN, SARıOĞLU, E, ALTUN, GAMZE, AKÇA, O, GÜRKAN, VOLKAN, ALTUN, GAMZE

2022-09-01, Özger H., ALPAN B., Salduz A., GÜRKAN V., Sungur M., Valiyev N., Eralp L., GÜRKAN, VOLKAN

© 2021, The Author(s).Aim: Mega-prosthetic reconstruction is the most common treatment method for massive osteoarticular defects caused by tumor resection around the knee. The new implant is a highly modular rotational-hinged megaprosthesis system with a distinct pentagonal stem geometry and variable implantation options. The aim of this study is to present the mid-term implant survival characteristics, functional and radiological results and mechanical complication profile of the new megaprosthesis. Methods: One hundred and one mega-prosthetic knee reconstruction procedures in 90 patients (M/F: 51/39) utilizing the new implant system were retrospectively analyzed. In 68 patients, the megaprosthesis was used for primary reconstruction following tumor resection while it was used for revision of other implants in 22. The mean age was 28.5 (7–66) years and the mean follow-up was 59.2 (24–124) months. The most common primary pathology was osteosarcoma with 63–70% patients, the most common anatomical site of involvement was the distal femur with 56–62% patients. Results: Henderson Type 2 failure (aseptic loosening) was seen in only 2–2.2% patients while Type 3 (structural failure) was seen in 29–32.2% Although the 5-year anchorage survival rate was 94.3%, overall mechanical implant survival was 76.1% at 5 years due to a relatively high failure rate in the first-generation hinge mechanism of the implant. The 5-year hinge survival rate demonstrated a significant improvement rate from 61.7% to 87.2% between the first and second generations of the implant (p = 0.027). The mean MSTS score was 24 out of 30 (14–29). The mean cumulative ISOLS radiographic score for index megaprosthesis operations was 19.7 (12–24), which corresponded to excellent outcome. Conclusion: The new megaprosthesis system is a reliable choice for the reconstruction of tumor-related massive osteoarticular defects around the knee. Although long-term follow-up is necessary for a definitive evaluation of the implant\"s survival characteristics, midterm follow-up yields exceptional anchorage properties related to pentagonal stem geometry with very good functional outcomes.

2018-01-01, GÜRKAN, VOLKAN, SÖNMEZ, FATMA CAVİDE, ATASOY, SEZEN, GÜRKAN, VOLKAN, SÖNMEZ, FATMA CAVİDE, ATASOY, SEZEN

Kötü huylu sinir kılıfı tümörleri; Kötü huylu periferik sinir kılıfı tümörü (MPSKT), Kötü huylu granüler hücreli tümör ve Ektomezenkimoma olarak sınıflandırılmaktadır. MPSKT dışındaki tümörler oldukça ender görülmektedir. MPSKT, tüm yumuşak doku sarkomları içerisinde %5 gibi küçük bir orana sahiptir. Tipik olarak 20-50 yaşları arasında görülür ve kadınlar erkeklere oranla daha fazla etkilenmektedir. Alt ekstremiteler lezyonların en sık rastlandığı yerlerdir. Çoğu MPSKT siyatik sinir gibi büyük periferal sinirleri tutar. Hastalarda gittikçe büyüyen kitle varlığıyla beraber nöropatik semptomlar da gözlenebilir. Görüntülemede manyetik rezonans (MR) öncelikli tercihtir. Kötü huylu damar tümörleri ise damar endotelinden kaynaklanan lezyonlardır. Tüm yaşlarda görülmesine rağmen yedinci dekatta daha sık rastlanırlar. Çoğu olguda etyoloji belirsizdir ancak bazı vakaların radyasyonla ilişkili olduğu bilinmektedir. Sıklıkla alt ekstremitelere lokalizedir. Dünya Sağlık Örgütü (WHO) kötü huylu damar tümörlerini farklı alt tiplere ayırmış olmakla beraber ön sırada "anjiyosarkom" gelmektedir. Bu tümörler oldukça agresif olup, yüksek mortalite oranına sahiptir.

2010-08-01T00:00:00Z, ORHUN, H, Gürkan, VOLKAN, DURSUN, M, ORHUN, E, SENER, B, GÜRKAN, VOLKAN