Person:
TOPÇU, GÜLAÇTI

Profile Picture
Status
Organizational Units
OrgUnit Logo
Organizational Unit
Job Title
First Name
GÜLAÇTI
Last Name
TOPÇU
Name
Email Address
Birth Date

Filters

2013 - 20205
Reset filters

Settings

Author: Topçu, Gülaçtı × Type: Article ×

Search Results

Now showing 1 - 5 of 5
  • No Thumbnail Available
    PublicationMetadata only
    Investigation of Anticholinesterase Activity of a Series of Salvia Extractsand the Constituents of Salvia staminea
    (2013-03-01) Topçu, Gülaçtı; Boğa, Mehmet; Kolak, Ufuk; Öztürk, Mehmet; Dirmenci, Tuncay; Bahadori, Fatemeh; Bütün, Burcu; TOPÇU, GÜLAÇTI; BAHADORİ, FATEMEH; BÜTÜN, BURCU
  • No Thumbnail Available
    PublicationMetadata only
    A High-Performance Liquid Chromatographic Method for the Determination of Meropenem in Serum
    (2020-02-01T00:00:00Z) Dincel, Demet; Topçu, Gülaçtı; DİNCEL, DEMET; TOPÇU, GÜLAÇTI
  • No Thumbnail Available
    PublicationMetadata only
    Synthesis of new fatty acid derivatives of oleanane and ursane triterpenoids and investigation of their in vitro cytotoxic effects on 3T3 fibroblast and PC3 prostate cancer cell lines
    (2020-09-01T00:00:00Z) Şenol, Halil; Çokuludağ, Kübra; Aktaş, Asude Sena; Atasoy, Sezen; Dağ, Aydan; Topçu, Gülaçtı; ŞENOL, HALIL; ATASOY, SEZEN; DAĞ, AYDAN; TOPÇU, GÜLAÇTI
  • No Thumbnail Available
    PublicationMetadata only
    Adaçayı Yaprağı, Kara Şalba
    (2018-10-01) Tan, Nur; Yazıcı Tütüniş, Seçil; Yeşil, Yeter; Ekinci, Miraç; Topçu, Gülaçtı; ALİM TORAMAN, GÜLBAHAR ÖZGE; TOPÇU, GÜLAÇTI
  • Thumbnail Image
    PublicationOpen Access
    Natural Alkaloids as Potential Anti-Coronavirus Compounds
    (2020-12-01T00:00:00Z) Topçu, Gülaçtı; Şenol, Halil; Alim Toraman, Gülbahar Özge; Altan, Vecdi Melih; TOPÇU, GÜLAÇTI; ŞENOL, HALIL; ALİM TORAMAN, GÜLBAHAR ÖZGE; ALTAN, VECDİ MELİH
    Coronaviruses are causative agents of the last three epidemics/pandemic; Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) and the last one Severe Acute Respiratory Syndrome-Cov-2 (SARS-CoV-2). Although meta-analysis of treatment studies against these three coronaviruses found no clear benefit of any spesific regimen, currently, remdesivir and favipiravir are promising potential therapies for SARS-CoV-2. On the other hand, since natural products have always played a crucial role in drug discovery and development process against various diseases, many groups in the world, are now trying to find new or repurposed natural or naturally originated drugs against viruses and coronaviruses. Secondary metabolites of the plants, particularly alkaloids and terpenoids have been exhibited strong antimicrobial and anticancer activities besides synthetic drugs and other natural compounds (nucleosides and nucleotides and bacterial and fungi originated ones). The first isolated secondary metabolites have been converted into important drugs since 1800’s such as morphine, codeine, cocaine, and quinine have alkaloid skeleton as well as some of the recent anticancer drugs vinblastine, vincristine, taxol, etc. This review includes the last two decades of publications about natural alkaloids rather than their plant extracts which showed some promising results against coronaviruses. Marine organisms are also another rich source to discover new lead drugs, however they were excluded in the present review article.