Person: MATUR, ZELİHA
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Publication Metadata only Somatosensory Evoked Potentials In Patients With Juvenile Myoclonic Epilepsy(2016-01-01T00:00:00Z) Ozemir, Zeynep Aydin; Matur, ZELİHA; BAYKAL, Betül; ÖGE, Ali Emre; MATUR, ZELİHAWhile a small number of studies dealing with somatosensory evoked potential (SEP) have demonstrated hyperexcitability in the primary somatosensory cortex of juve-nile myoclonic epilepsy (JME) patients, the underlying mechanisms have yet to be illuminated. Determination of higher cortical SEP responses in some JME patients and recordings of very high amplitude responses, called -giant SEP,- in a specific subgroup may indicate a clinical and possibly genetic heterogeneity within JME patients. In the present review, the findings of previous studies concerned with SEP in JME patients are summarized, and their importance regarding JME etiopathogenesis and related clinical findings is discussed.Publication Metadata only Restless Legs Syndrome in Patients with Behcet-s Disease and Multiple Sclerosis: Prevalence, Associated Conditions and Clinical Features(2020-03-01T00:00:00Z) Onalan, Aysenur; Matur, ZELİHA; Pehlivan, Munevver; Akman, Gulsen; MATUR, ZELİHAIntroduction: To investigate the prevalence and characteristics of Restless Legs Syndrome (RLS) in patients with Behcet-s Disease (BD) and Multiple Sclerosis (MS).Publication Metadata only Clinical, Electrophysiological, and Serological Evaluation of Patients with Cramp-Fasciculation Syndrome(2017-06-01T00:00:00Z) Poyraz, Muruvvet; Matur, ZELİHA; Aysal, Fikret; TÜZÜN, Erdem; Hanoglu, Lutfu; ÖGE, Ali Emre; MATUR, ZELİHAIntroduction: Cramp-fasciculation syndrome (CFS) is a rare peripheral nerve hyperexcitability syndrome. There are only a few reports on clinical and serological profile of a CFS cohort that was followed up by a single outpatient clinic.Publication Metadata only Exonic duplication CNV of NDRG1 associated with autosomal-recessive HMSN-Lom/CMT4D(2014-05-01T00:00:00Z) Okamoto, Yuji; Goksungur, Meryem Tuba; Pehlivan, Davut; Beck, Christine R.; Gonzaga-Jauregui, Claudia; Muzny, Donna M.; Atik, Mehmed M.; Carvalho, Claudia M. B.; Matur, ZELİHA; BAYRAKTAR, Şerife; Boone, Philip M.; Akyuz, Kaya; Gibbs, Richard A.; Battaloglu, Esra; Parman, Yesim; Lupski, James R.; MATUR, ZELİHAPurpose: Copy-number variations as a mutational mechanism contribute significantly to human disease. Approximately one-half of the patients with Charcot-Marie-Tooth (CMT) disease have a 1.4Mb duplication copy-number variation as the cause of their neuropathy. However, non-CMTIA neuropathy patients rarely have causative copy-number variations, and to date, autosomal-recessive CMT disease has not been associated with copy-number Variation as a mutational mechanism.Publication Metadata only Erratum: Evaluation of OnabotulinumtoxinA Treatment in Patients with Concomitant Chronic Migraine and Temporomandibular Disorders.(2019-03-01T00:00:00Z) Kocaman, Gülşen; Kahraman, Neşe; Köseoğlu, Banu Gürkan; Bilgiç, Başar; Matur, ZELİHA; Ertaş, Mustafa; Gülşen, Yeşim; Baykan, Betul; MATUR, ZELİHAPublication Metadata only The Impact of Affective State on Quality of Life in Focal Epilepsy in Turkey(2019-04-01T00:00:00Z) TAŞKIRAN, EMİNE; Matur, ZELİHA; Gul, Gunay; BEBEK, Nerses; BAYKAL, Betül; Gokyigit, Aysen; Gurses, Candan; MATUR, ZELİHAContext: Seizures and accompanying situations including social, medical, and psychiatric problems threaten the quality of life (QOL) in patients with epilepsy. The World Health Organization defines health is a state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity. Aims: This study examines the prevalence of both depression and anxiety symptoms and also impact of the affective state on QOL in patients with focal epilepsy in Turkey. Settings and Design: One hundred and five patients with focal epilepsy over 18 years old were included in this study. The patients were classified into four groups according to the presence of AS and seizure control. Subjects and Methods: Patients- affective symptoms (AS) and QOL were examined using the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and QOL in Epilepsy Inventory-31 (QOLIE-31). Statistical Analysis Used: We used descriptive statistics, Chi-square test, independent samples t-test, one-way analysis of variance, Mann-Whitney U-test, Kruskal-Wallis H-test, and also Pearson-s and Spearman-s correlation test for correlations. Results: There were positive correlations between total QOLIE-31 score and epilepsy surgery, employment, and seizure freedom, whereas negative correlations were found with antiepileptic drug use, anxiety, and depression. Statistically significant differences were found in QOLIE-31 totals and subscores between Groups 3 and 4 (P < 0.05). Conclusions: The presence of AS has a negative impact on QOL in patients with focal epilepsy. Physicians should be aware that psychiatric comorbidities in epilepsy have a severe impact and epilepsy treatment requires comprehensive management.Publication Metadata only A SOD2 Polymorphism is Associated with Abnormal Quantitative Sensory Testing in Type 2 Diabetic Patients(2018-09-01T00:00:00Z) Isikli, Ali; Kubat-Uzum, Ayse; SATMAN, İlhan; Matur, ZELİHA; Oge, A. Emre; KÜÇÜKALİ, Cem İsmail; TÜZÜN, Erdem; Erden, Sacide; ÖZKÖK, Elif; MATUR, ZELİHAIntroduction: Diabetes mellitus (DM) affects peripheral nerves inducing diabetic polyneuropathy (DPN). Mitochondria! dysfunction and oxidative stress are potential causes of DPN.Publication Metadata only Autosomal Dominant Cortical Tremor, Myoclonus, and Epilepsy Syndrome mimicking Juvenile Myoclonic Epilepsy(2016-09-01T00:00:00Z) Aydin Ozemir, Zeynep; Oguz Akarsu, Emel; Matur, ZELİHA; Oge, Ali Emre; BAYKAL, Betül; MATUR, ZELİHAIntroduction: Autosomal dominant cortical tremor, myoclonus, and epilepsy (ADCME) syndrome is a genetically heterogeneous and under-recognized disease characterized by tremulous movements mimicking essential tremor, myoclonus, and rare generalized tonic-clonic seizures. Here we described the clinical and electrophysiological features of three siblings with ADCME syndrome mimicking juvenile myoclonic epilepsy (JME).Publication Metadata only Effect of socks on the assessment of vibration sensation.(2013-10-24T00:00:00Z) Meral, R C; Matur, ZELİHA; Dertsiz, B; Oge, A E; MATUR, ZELİHAPublication Metadata only Sensorimotor Integration During Motor Learning: Transcranial Magnetic Stimulation Studies(2017-12-01T00:00:00Z) Matur, ZELİHA; ÖGE, Ali Emre; MATUR, ZELİHAThe effect of sensory signals coming from skin and muscle afferents on the sensorimotor cortical networks is entitled as sensory-motor integration (SMI). SMI can be studied electrophysiologically by the motor cortex excitability changes in response to peripheral sensory stimulation. These changes include the periods of short afferent inhibition (SAI), afferent facilitation (AF), and late afferent inhibition (LAI). During the early period of motor skill acquisition, motor cortex excitability increases and changes occur in the area covered by the relevant zone of the motor cortex. In the late period, these give place to the morphological changes, such as synaptogenesis. SAI decreases during learning the motor skills, while LAI increases during motor activity. In this review, the role of SMI in the process of motor learning and transcranial magnetic stimulation techniques performed for studying SMI is summarized.