Person: MATUR, ZELİHA
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Publication Metadata only Somatosensory Evoked Potentials In Patients With Juvenile Myoclonic Epilepsy(2016-01-01T00:00:00Z) Ozemir, Zeynep Aydin; Matur, ZELİHA; BAYKAL, Betül; ÖGE, Ali Emre; MATUR, ZELİHAWhile a small number of studies dealing with somatosensory evoked potential (SEP) have demonstrated hyperexcitability in the primary somatosensory cortex of juve-nile myoclonic epilepsy (JME) patients, the underlying mechanisms have yet to be illuminated. Determination of higher cortical SEP responses in some JME patients and recordings of very high amplitude responses, called -giant SEP,- in a specific subgroup may indicate a clinical and possibly genetic heterogeneity within JME patients. In the present review, the findings of previous studies concerned with SEP in JME patients are summarized, and their importance regarding JME etiopathogenesis and related clinical findings is discussed.Publication Metadata only The Impact of Affective State on Quality of Life in Focal Epilepsy in Turkey(2019-04-01T00:00:00Z) TAŞKIRAN, EMİNE; Matur, ZELİHA; Gul, Gunay; BEBEK, Nerses; BAYKAL, Betül; Gokyigit, Aysen; Gurses, Candan; MATUR, ZELİHAContext: Seizures and accompanying situations including social, medical, and psychiatric problems threaten the quality of life (QOL) in patients with epilepsy. The World Health Organization defines health is a state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity. Aims: This study examines the prevalence of both depression and anxiety symptoms and also impact of the affective state on QOL in patients with focal epilepsy in Turkey. Settings and Design: One hundred and five patients with focal epilepsy over 18 years old were included in this study. The patients were classified into four groups according to the presence of AS and seizure control. Subjects and Methods: Patients- affective symptoms (AS) and QOL were examined using the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and QOL in Epilepsy Inventory-31 (QOLIE-31). Statistical Analysis Used: We used descriptive statistics, Chi-square test, independent samples t-test, one-way analysis of variance, Mann-Whitney U-test, Kruskal-Wallis H-test, and also Pearson-s and Spearman-s correlation test for correlations. Results: There were positive correlations between total QOLIE-31 score and epilepsy surgery, employment, and seizure freedom, whereas negative correlations were found with antiepileptic drug use, anxiety, and depression. Statistically significant differences were found in QOLIE-31 totals and subscores between Groups 3 and 4 (P < 0.05). Conclusions: The presence of AS has a negative impact on QOL in patients with focal epilepsy. Physicians should be aware that psychiatric comorbidities in epilepsy have a severe impact and epilepsy treatment requires comprehensive management.Publication Metadata only Analysis of the tremor in juvenile myoclonic epilepsy(2016-12-01T00:00:00Z) Aydin-Ozemir, Zeynep; Matur, ZELİHA; BAYKAL, Betül; BİLGİÇ, Başar; Tekturk, Pinar; BEBEK, Nerses; Gurses, Candan; Hanagasi, Hasmet; ÖGE, Ali Emre; MATUR, ZELİHAPurpose: We aimed to investigate juvenile myoclonic epilepsy (JME) patients complaining of tremor unrelated to valproate (VPA) treatment and evaluate if there were differences between JME patients with and without tremor and essential tremor (ET) patients to exclude comorbidity.Publication Metadata only Autosomal Dominant Cortical Tremor, Myoclonus, and Epilepsy Syndrome mimicking Juvenile Myoclonic Epilepsy(2016-09-01T00:00:00Z) Aydin Ozemir, Zeynep; Oguz Akarsu, Emel; Matur, ZELİHA; Oge, Ali Emre; BAYKAL, Betül; MATUR, ZELİHAIntroduction: Autosomal dominant cortical tremor, myoclonus, and epilepsy (ADCME) syndrome is a genetically heterogeneous and under-recognized disease characterized by tremulous movements mimicking essential tremor, myoclonus, and rare generalized tonic-clonic seizures. Here we described the clinical and electrophysiological features of three siblings with ADCME syndrome mimicking juvenile myoclonic epilepsy (JME).