2016-01-01T00:00:00Z, Ozemir, Zeynep Aydin, Matur, ZELİHA, BAYKAL, Betül, ÖGE, Ali Emre, MATUR, ZELİHA

While a small number of studies dealing with somatosensory evoked potential (SEP) have demonstrated hyperexcitability in the primary somatosensory cortex of juve-nile myoclonic epilepsy (JME) patients, the underlying mechanisms have yet to be illuminated. Determination of higher cortical SEP responses in some JME patients and recordings of very high amplitude responses, called -giant SEP,- in a specific subgroup may indicate a clinical and possibly genetic heterogeneity within JME patients. In the present review, the findings of previous studies concerned with SEP in JME patients are summarized, and their importance regarding JME etiopathogenesis and related clinical findings is discussed.

2016-12-01T00:00:00Z, Aydin-Ozemir, Zeynep, Matur, ZELİHA, BAYKAL, Betül, BİLGİÇ, Başar, Tekturk, Pinar, BEBEK, Nerses, Gurses, Candan, Hanagasi, Hasmet, ÖGE, Ali Emre, MATUR, ZELİHA

Purpose: We aimed to investigate juvenile myoclonic epilepsy (JME) patients complaining of tremor unrelated to valproate (VPA) treatment and evaluate if there were differences between JME patients with and without tremor and essential tremor (ET) patients to exclude comorbidity.

2017-12-01T00:00:00Z, Matur, ZELİHA, ÖGE, Ali Emre, MATUR, ZELİHA

The effect of sensory signals coming from skin and muscle afferents on the sensorimotor cortical networks is entitled as sensory-motor integration (SMI). SMI can be studied electrophysiologically by the motor cortex excitability changes in response to peripheral sensory stimulation. These changes include the periods of short afferent inhibition (SAI), afferent facilitation (AF), and late afferent inhibition (LAI). During the early period of motor skill acquisition, motor cortex excitability increases and changes occur in the area covered by the relevant zone of the motor cortex. In the late period, these give place to the morphological changes, such as synaptogenesis. SAI decreases during learning the motor skills, while LAI increases during motor activity. In this review, the role of SMI in the process of motor learning and transcranial magnetic stimulation techniques performed for studying SMI is summarized.

2017-06-01T00:00:00Z, Poyraz, Muruvvet, Matur, ZELİHA, Aysal, Fikret, TÜZÜN, Erdem, Hanoglu, Lutfu, ÖGE, Ali Emre, MATUR, ZELİHA

Introduction: Cramp-fasciculation syndrome (CFS) is a rare peripheral nerve hyperexcitability syndrome. There are only a few reports on clinical and serological profile of a CFS cohort that was followed up by a single outpatient clinic.

2013-01-01T00:00:00Z, Matur, ZELİHA, Kaymaz, Aysenur, Altunrende, Burcu, Tuncer, Serdar, Gungor-Tuncer, Ozlem, Akman-Demir, Gulsen, ÖGE, Ali Emre, MATUR, ZELİHA

During the course of human immunodeficiency virus (HIV) infection, which leads to a chronic infectious disease that suppresses the cellular immune system, various types of peripheral neuropathies can be seen in different stages from seroconversion to the advanced stage. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) usually occurs in early or mid-stage of the disease. In this study, we are presenting a 66 year-old man who was admitted to our clinic due to progressive and predominantly sensorial symptoms and signs of CIDP, who had recently been operated for carpal tunnel syndrome which was suggested by electromyography even though he had complains of diffuse polyneuropathy symptoms from the beginning. During his diagnostic work-up cerebrospinal fluid (CSF) analysis had revealed elevated protein and pleocytosis, and further investigation revealed HIV-1 infection. Areas of demyelination are very common in usual entrapment zones in the course of CIDP, which is a neuropathy with multi-segment demyelination in peripheral nerves and/nerve roots. Without a detailed patient history and examination, and a detailed EMG evaluation, a diffuse neuropathy can be misdiagnosed as an entrapment neuropathy. As it is in our case, this can lead to an unnecessary surgery and a delay in the actual diagnosis. CSF examination is very valuable for the investigation of the etiology of chronic demyelinating polyneuropaties. In CIDP patients, only protein elevation can be seen in CSF analysis; however, in the presence of pleocytosis, other diseases such as chronic infections, particularly HIV infection, other chronic inflammatory diseases, and malignant infiltration of nerve roots should be investigated.

2018-03-01T00:00:00Z, KOCASOY ORHAN, Elif, Baysal Kirac, Leyla, YALİNAY DİKMEN, PİNAR, Matur, ZELİHA, Ertas, Mustafa, ÖGE, Ali Emre, Deymeer, Feza, Yazici, Jale, BASLO, Mehmet Barış, MATUR, ZELİHA

Introduction: Electrodiagnostic evaluation provides an important extension to the neurological examination for the evaluation of pediatric neuromuscular disease. Many pediatric neuromuscular diseases are analogous to those seen in the adult. However, the relative frequency of these illnesses varies greatly when different age populations are compared. The purpose of the present study is to provide a retrospective analysis of children referred to our electromyography (EMG) laboratory for electrophysiological examinations.

2020-10-01T00:00:00Z, GENÇ, Ayşenur, İŞLER, Sabri Cemil, KESKİN, Cengizhan, ÖGE, Ali Emre, Matur, ZELİHA, MATUR, ZELİHA

The aim of this study was electromyographic description of changes in swallowing before and after bilateral sagittal split ramus osteotomy. In this prospective study, twenty-eight patients were divided into 3 groups according to the occlusion pattern: Group I (Angle Class III), Group II (Angle Class II), and Control (Class I). Serial cone-beam computed tomography analyses and electromyographic data were collected preoperatively, 1st and 6th months after setback surgery in Group I, and advancement surgery in Group II. Swallowing reflex with 3-20 ml water bolus were studied. Patients were further divided into two subgroups according to the magnitude of relapse. The mean setback of the mandible was 4.62 +/- 1.92 mm in Group I, and the mean advancement was 4.19 +/- 2.00 mm in Group II. Mandibular relapse rate was 17.40%. Oral preparation phase shortened after surgery in both study groups. Two subjects in Group II and one in Group I had piecemeal deglutition, and two of them became normal postoperatively. Most of the swallowing durations of the relapsed cases were longer than those of stabilized patients. Important clinical considerations are as follows: the oral preparation period becomes shorter after surgery; piecemeal deglutition may disappear after treatment; and individuals with a longer oral period and piecemeal deglutition may have increased tendency to skeletal relapse. This multidisciplinary study enhances our understanding of the adaptive response to the swallowing reflex after orthognathic surgery and provides novel insight into the association between the submental muscle activity and relapse in orthognathic patients.