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AKÇAKAYA, ADEM

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ADEM
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AKÇAKAYA
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Start date: 2020 × End date: 2024 ×

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Now showing 1 - 10 of 48
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    Evaluation of Parathyroid allo-transplantation with the Presence of Auto-CASR Antibody
    (2022-05-01) Selepcioğlu Kaya H.; Göncü B. S.; Ersoy Y. E.; Akçakaya A.; SELEPCİOĞLU KAYA, HARİKA; GÖNCÜ, BEYZA SERVET; ERSOY, YELIZ EMINE; AKÇAKAYA, ADEM
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    PublicationOpen Access
    Report of a Case of Signet Ring Carcinoma Presenting as Gastric Mucosal Thickening: A Diagnostic Dilemma
    (2021-01-01T00:00:00Z) Karatoprak, Cumali; Akçakaya, Adem; Şentürk, Hakan; Çoban, Ganime; Şahin, Nurhan; Türk, Hacı Mehmet; KARATOPRAK, CUMALİ; AKÇAKAYA, ADEM; ŞENTÜRK, HAKAN; ÇOBAN, GANİME; ŞAHİN, NURHAN; TÜRK, HACI MEHMET
    The number of cancer cases has been increasing worldwide. Early diagnosis and tumor resection remain as the most effective treatments for gastric cancer. However, early diagnosis is not always possible as it is frequently not possible to make treatment decisions without pathologic diagnosis in patients with clinically suspected cancer. This causes delays in diagnosing cancer. We presented a 58 years old woman with gastric signet ring cell carcinoma that could not be diagnosed despite using four different methods of stomach biopsies. We aimed to emphasize that despite the use of advanced methods, if clinical cancer in non-diagnosed cases is suspected, we should be more aggressive for early diagnosis.
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    Clinicopathological features of gastroenteropancreatic neuroendocrine neoplasms: a retrospective single-center experience
    (2021-03-01T00:00:00Z) ŞEKERCİ, ABDÜSSELAM; TÜRK, HACI MEHMET; DEMİR, Tarık; ŞEKER, Mesut; AKÇAKAYA, Adem; ARICI, Dilek Sema; ŞEKERCİ, ABDÜSSELAM; TÜRK, HACI MEHMET; DEMİR, TARıK; ŞEKER, MESUT; AKÇAKAYA, ADEM; ARICI, DILEK SEMA
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    Editörden
    (2020-10-01T00:00:00Z) Akçakaya, Adem; AKÇAKAYA, ADEM
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    PublicationOpen Access
    Timing of laparoscopic cholecystectomy in acute cholecystitis.
    (2021-02-01T00:00:00Z) Yuksekdag, S; Bas, G; Okan, I; Karakelleoglu, A; Alimoglu, O; Akcakaya, Adem; Sahin, M; AKÇAKAYA, ADEM
    Background: Timing of laparoscopic cholecystectomy (LC) in acute cholecystitis (AC) is still debated. Aims: The aim of this study was to investigate the effect of timing on operative results; from the first appearance of symptoms to the operation. Methods: The study included 57 sequential patients operated laparoscopically for AC. Patients operated within the first 3 days of admission (Group 1), those operated between 4th and 7th days (Group 2) and those operated after 7th day (Group 3) were evaluated and compared with respect to demographics, time from admission to operation, duration of operation, adhesion score, complications, conversion rates, duration of hospital stay, morbidity and mortality rates, bile culture results, and histopathological evaluation. Results: A total of 63% of the patients were female and 21 (37%) were male. The mean age was 48 years (range, 21-74). There was no significant difference among the groups with respect to demographics (P > 0.05, for each). The duration of operation was significantly shorter in Group 1 than both Groups 2 and 3 (P < 0.05 and P < 0.001, respectively). Duration of operation was also significantly shorter in Group 2 than Group 3 (P < 0.001). Group 1 had significantly fewer adhesions compared to Group 2 and Group 3 (P < 0.05 and P < 0.001, respectively), and no significant difference was found between Group 2 and Group 3 (P > 0.05). Duration of hospital stay was significantly shorter in Group 1 compared to Group 2 and Group 3 (P < 0.001) and also was significantly shorter in Group 2 than Group 3 (P < 0.05). Group 1 had significantly lower rate of culture proliferation than Group 3 (P < 0.001), whereas no significant differences were evident in other inter-group analyses (P > 0.05, for each). Conclusion: LC can safely be performed within 7 days of admission in cases of AC.
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    The Role of Faith in Coping with Cancer among Palliative Care Patients in Turkey
    (Oxford University Press, London , 2022-03-01) Akçakaya A.; Can G.; AKÇAKAYA, ADEM
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    AN ALTERNATIVE AND UP-TO-DATE RECOMMENDATION FOR A PROPER SITE FOR PARATHYROID TRANSPLANTATION: THE OMENTUM
    (2023-05-26) Ersoy Y. E.; Göncü B. S.; Yücesan E.; Selepcioğlu Kaya H.; Kazancıoğlu R.; Akçakaya A.; ERSOY, YELIZ EMINE; GÖNCÜ, BEYZA SERVET; SELEPCİOĞLU KAYA, HARİKA; KAZANCIOĞLU, RÜMEYZA; AKÇAKAYA, ADEM
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    PublicationOpen Access
    Problems of Healthcare Professionals in COVID-19 Pandemic
    (2021-01-01T00:00:00Z) Akçakaya, Adem; AKÇAKAYA, ADEM
    As is known, the Coronavirus disease-19 (COVID-19) pandemic has started in China in November-December 2019 and then spread to the whole world (1). It was declared as an international public health emergency by The World Health Organization (WHO) on January 30, 2020, and later described as a pandemic (2). The disease has spread all over the world in a very short time. Of the patients, 28.5% were in Asia, 24.1% in North America, 23.7% in Europe, 19.8% in South America, and 3.7% in Africa. In our country, the first patient was announced in March, and the first death on March 18.
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    PublicationOpen Access
    Current Status of Approach to Thyroid Nodules
    (2022-04-01T00:00:00Z) AKÇAKAYA, Adem; AKÇAKAYA, ADEM
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    Hücre Mikroenkapsülasyonunda Manuel ve Kapsülasyon Sisteminin Hücre İzolasyon Tipi ve Aljinat Yüzdesine Bağlı Verimliliğinin Karşılaştırılması
    (2021-08-01T00:00:00Z) Düzenli, Ömer Faruk; Göncü, Beyza Servet; Selepcioğlu, Harika; Yücesan, Emrah; Ersoy, Yeliz Emine; Akçakaya, Adem; GÖNCÜ, BEYZA SERVET; YÜCESAN, EMRAH; ERSOY, YELIZ EMINE; AKÇAKAYA, ADEM
    Amaç: Birçok endüstriyel sektörde kullanılan polimer malzemeler sağlık bilimlerinde de farklı işlemlerde kullanılmaktadır. Bu işlemlerden biri olan enkapsülasyon sistemi hücre nakli gibi terapötik uygulamalarda tercih edilmektedir. Enkapsülasyon çalışmalarında uygulanacak yaklaşıma göre kapsül yapısında kullanılacak polimer malzeme ve oluşan kapsül boyutu değişmektedir. Aljinat, kahverengi alglerden elde edilen, içeriğindeki farklı polimerik blok oranlarına bağlı olarak değişiklik gösteren doğal polimerlerden biridir. Bu çalışmada, kapsülasyon aşaması için kullanılacak olan değişik aljinat yüzdeleri uygulanarak paratiroid hücrelerinde ideal mikroenkapsülasyon prosedürlerinin belirlenmesi amaçlanmaktadır.Gereç ve Yöntem: Çalışmada sekonder hiperparatiroidi hastasından alınan bir adet paratiroid hiperplazi dokusundan mekanik ve enzimatik izolasyon yöntemleriyle hücre eldesi gerçekleştirilmiştir. İki farklı aljinat yüzdesi kullanarak hem manuel olarak hem de kapsülasyon cihazında otomatize olarak iki farklı akış hızı değerlendirilmiştir. Mikroenkapsüle edilen hücreler 64-79 gün boyunca in vitro olarak parathormon miktarları ölçülerek takip edilmiştir.Bulgular: Değerlendirilen aljinat yüzdelerinden %2’lik konsantrasyona sahip mikroenkapsüllerin oluşturulmasında kapsülasyon cihazında kullanılan 2 mL/dk akış hızıyla morfolojik stabilite gözlenmiştir. Ayrıca parathormon salınımı açısından hücre izolasyon tipi ve aljinat yüzdeleri arasında benzer sonuçlar elde edilmiştir.Sonuç: Uzun süreli mikroenkapsülasyon verimliliğinin arttırılması için yapısal ve fonksiyonel açıdan birçok parametrenin belirlenmesi gerekmektedir. Bu çalışma ile enzimatik izolasyon metoduyla elde edilen paratiroid hücrelerinin kapsülasyon sistemi kullanılarak artan akış hızında daha stabil bir yapı oluşturdukları belirlenmiştir.