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BAYRAKTAR, HAVVANUR

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Kurumdan Ayrılmıştır

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HAVVANUR

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BAYRAKTAR

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Now showing 1 - 3 of 3
  • Publication
    The effect of platelet-rich fibrin on wound healing following strabismus surgery
    (2022-06-01T00:00:00Z) TUĞCU, Betül; BAYRAKTAR, HAVVANUR; EKİNCİ, CANSU; Kucukodaci, Zafer; TUNALI, Mustafa; NUHOĞLU, FADİME; TUĞCU, BETÜL; BAYRAKTAR, HAVVANUR; EKİNCİ, CANSU; TUNALI, MUSTAFA; NUHOĞLU, FADİME
    Purpose To investigate the effect of platelet-rich fibrin (PRF) on post-operative wound healing following strabismus surgery in a rabbit model. Methods Nine New Zealand white rabbits were involved in the study. One of these nine rabbits was kept in control without having any operation. Both eyes of eight rabbits underwent superior rectus muscle (SRM) resection. After resection of SRM, PRF was applied to SRM of the right eyes. In the left eye, SRM was not wrapped with PRF and served as a control. The rabbits were sacrificed and enucleated 6 weeks after the surgery. Inflammation and vascular proliferation were assessed by staining with haematoxylin-eosin. Scar and fibrosis were examined by the Masson trichrome staining. Immunohistochemical staining was performed for a vascular endothelial growth factor (VEGF) and alpha-smooth muscle actin (alpha-SMA). Results There was no significant difference in terms of inflammation (p = 0.535), vascularization (p = 0.602), and fibrosis (p = 0.745) between the eyes. Immunohistochemical staining for VEGF demonstrated no significant difference (p = 0.745). However, significant staining for alpha-SMA was detected in PRF-treated eyes compared with control eyes (p = 0.037). Conclusion Consistent with the hypothesis that PRF facilitates wound healing as a biocatalyst, there was only a significant difference for alpha-SMA related to myofibroblast activity which is important for wound remodelling. Future comprehensive studies are needed to extend these results.
  • Publication
    Regional analysis of segmented-macular structure in patients with myopic anisometropia
    (2021-06-01T00:00:00Z) KIRIK, FURKAN; EKİNCİ, CANSU; AKBULUT, ERSİN; BAYRAKTAR, HAVVANUR; Ozdemir, Hakan; KIRIK, FURKAN; EKİNCİ, CANSU; AKBULUT, ERSİN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKAN
    Purpose To compare intraretinal layers between the eyes in patients with myopic anisometropia, and evaluate the relationship between the layers with spherical equivalent (SE) and axial length (AL). Methods In this retrospective study, the more myopic (MM) and fellow (F) eyes of 41 patients with myopic anisometropia, and 38 emmetropic (+/- 0.50 diopter) control (C) eyes were inclueded. Intraretinal layer segmentation was performed by optical coherence tomography. Global volumes of retinal layers and their thicknesses in nine macular regions were compared. Correlation analysis was used to determine the relationship with SE and AL in each layer. Results Total retinal, ganglion cell (GCL), inner nuclear (INL), and outer plexiform (OPL) layer volumes in MM eyes were less than in C eyes, while INL and OPL were less than in F eyes. There was no difference in the fovea, except for the retinal pigment epithelium. In MM eyes, only INL and OPL were thin in at least one perifoveal and parafoveal quadrant compared to F eyes. Only INL and OPL thicknesses were significantly correlated with both SE and AL in all perifoveal quadrants. In contrast to the thinning found in MM eyes, the only layer in which thickening was detected to compare to C eye was nerve fiber layer (NFL), which correlated positively with SE and negatively with AL. Conclusion While the fovea is less affected by myopia, thinning becomes remarkable in the perifoveal quadrants. Despite thinning in many layers, especially INL and OPL, NFL thickening may be seen due to myopia.
  • Publication
    Acute Phototoxic Retinopathy due to Infrared Heater
    (2020-09-01T00:00:00Z) Kırık, Furkan; Çevik, Neslihan; Bayraktar, Havvanur; Özdemir, Mehmet Hakan; KIRIK, FURKAN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKAN