Person: BAYRAKTAR, HAVVANUR
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Publication Metadata only Acute Phototoxic Retinopathy due to Infrared Heater(2020-09-01T00:00:00Z) Kırık, Furkan; Çevik, Neslihan; Bayraktar, Havvanur; Özdemir, Mehmet Hakan; KIRIK, FURKAN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKANPublication Open Access Autologous Platelet-Rich Fibrin in the Treatment of Refractory Macular Holes(2019-11-06T00:00:00Z) Koytak, Arif; NUHOĞLU, FADİME; BAYRAKTAR, HAVVANUR; Ercan, Rukiye; Ozdemir, Hakan; KOYTAK, İBRAHİM ARİF; NUHOĞLU, FADİME; BAYRAKTAR, HAVVANUR; ERCAN, RUKIYE; ÖZDEMİR, MEHMET HAKANPurpose. To describe a novel method for the treatment of refractory macular holes. Methods. Two case reports on the use of autologous platelet rich fibrin (PRF), followed by sulfur hexafluoride gas tamponade to facilitate closure of refractory macular holes. Results. Macular holes were succesfully closed within a week in both cases. Best corrected Snellen visual acuities improved from counting fingers to 0.16 in the first case, and from 0.05 to 0.2 in the second case. No complication occurred during or a er the procedures. Conclusion. e use of autologous PRF seems to be a safe and effective alternative method for the treatment of refractory macular holes. Further experience and studies are required to assess the value of autologous PRF in the management of challenging macular hole cases of different etiologies. To the best of our knowledge, this is the first use of autologous PRF in the treatment of macular holes.Publication Metadata only Regional analysis of segmented-macular structure in patients with myopic anisometropia(2021-06-01T00:00:00Z) KIRIK, FURKAN; EKİNCİ, CANSU; AKBULUT, ERSİN; BAYRAKTAR, HAVVANUR; Ozdemir, Hakan; KIRIK, FURKAN; EKİNCİ, CANSU; AKBULUT, ERSİN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKANPurpose To compare intraretinal layers between the eyes in patients with myopic anisometropia, and evaluate the relationship between the layers with spherical equivalent (SE) and axial length (AL). Methods In this retrospective study, the more myopic (MM) and fellow (F) eyes of 41 patients with myopic anisometropia, and 38 emmetropic (+/- 0.50 diopter) control (C) eyes were inclueded. Intraretinal layer segmentation was performed by optical coherence tomography. Global volumes of retinal layers and their thicknesses in nine macular regions were compared. Correlation analysis was used to determine the relationship with SE and AL in each layer. Results Total retinal, ganglion cell (GCL), inner nuclear (INL), and outer plexiform (OPL) layer volumes in MM eyes were less than in C eyes, while INL and OPL were less than in F eyes. There was no difference in the fovea, except for the retinal pigment epithelium. In MM eyes, only INL and OPL were thin in at least one perifoveal and parafoveal quadrant compared to F eyes. Only INL and OPL thicknesses were significantly correlated with both SE and AL in all perifoveal quadrants. In contrast to the thinning found in MM eyes, the only layer in which thickening was detected to compare to C eye was nerve fiber layer (NFL), which correlated positively with SE and negatively with AL. Conclusion While the fovea is less affected by myopia, thinning becomes remarkable in the perifoveal quadrants. Despite thinning in many layers, especially INL and OPL, NFL thickening may be seen due to myopia.Publication Metadata only The effect of platelet-rich fibrin on wound healing following strabismus surgery(2022-06-01T00:00:00Z) TUĞCU, Betül; BAYRAKTAR, HAVVANUR; EKİNCİ, CANSU; Kucukodaci, Zafer; TUNALI, Mustafa; NUHOĞLU, FADİME; TUĞCU, BETÜL; BAYRAKTAR, HAVVANUR; EKİNCİ, CANSU; TUNALI, MUSTAFA; NUHOĞLU, FADİMEPurpose To investigate the effect of platelet-rich fibrin (PRF) on post-operative wound healing following strabismus surgery in a rabbit model. Methods Nine New Zealand white rabbits were involved in the study. One of these nine rabbits was kept in control without having any operation. Both eyes of eight rabbits underwent superior rectus muscle (SRM) resection. After resection of SRM, PRF was applied to SRM of the right eyes. In the left eye, SRM was not wrapped with PRF and served as a control. The rabbits were sacrificed and enucleated 6 weeks after the surgery. Inflammation and vascular proliferation were assessed by staining with haematoxylin-eosin. Scar and fibrosis were examined by the Masson trichrome staining. Immunohistochemical staining was performed for a vascular endothelial growth factor (VEGF) and alpha-smooth muscle actin (alpha-SMA). Results There was no significant difference in terms of inflammation (p = 0.535), vascularization (p = 0.602), and fibrosis (p = 0.745) between the eyes. Immunohistochemical staining for VEGF demonstrated no significant difference (p = 0.745). However, significant staining for alpha-SMA was detected in PRF-treated eyes compared with control eyes (p = 0.037). Conclusion Consistent with the hypothesis that PRF facilitates wound healing as a biocatalyst, there was only a significant difference for alpha-SMA related to myofibroblast activity which is important for wound remodelling. Future comprehensive studies are needed to extend these results.Publication Metadata only A novel tool reflecting the role of oxidative stress in the cataracts: thiol/disulfide homeostasis(2017-01-01) Elbay, AHMET; Ozer, Omer Faruk; ALTINISIK, Muhammed; ELBAY, Arif Emre; Sezer, TAHA; Bayraktar, HAVVANUR; OZDEMIR, Hakan; ELBAY, AHMET; ÖZER, ÖMER FARUK; SEZER, TAHA; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKANWe investigated serum and aqueous humor thiol/disulfide (T-D) homeostasis in patients with cataracts versus healthy controls. In total, 56 patients with cataracts and 49 healthy controls were enrolled in this case-control study. Serum total thiol (TT), native thiol (NT), and disulfide (DS) concentrations were determined using a novel automated measurement method. Additionally, DS/TT, DS/NT and NT/TT percentage ratios were compared between the groups. In comparison with the control group, serum NT levels and aqueous humor TT and NT levels were significantly lower (p<.05, p<.05 and p<.001, respectively), whereas serum and aqueous humor DS levels were significantly higher in cataract patients (p<.01 and p<.001). DS/TT and DS/NT ratios were significantly higher and the NT/TT ratio was lower in cataract patients in serum (p<.005) and aqueous humor samples (p<.001). In conclusion, serum T-D homeostasis may be useful as biochemical markers, indicating the role of oxidative stress in the development of cataracts. Further studies are needed to confirm the pathophysiological role of T-D homeostasis in cataractogenesis.Publication Metadata only Nadir Görülen Bir Keratit Etkeni Olarak Trichophyton tonsurans-Olgu Sunumu(2017-10-29) ELBAY, AHMET; BAYRAKTAR, HAVVANUR; ERCAN ÇETİNKAYA, Rukiye; SÜMBÜL GÜLTEPE, BİLGE; ELBAY, AHMET; BAYRAKTAR, HAVVANUR