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UZER, GÖKÇER

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Author: Elmadag, Mehmet × Rights: info:eu-repo/semantics/openAccess ×

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    PublicationOpen Access
    Safety of modified Stoppa approach for Ganz periacetabular osteotomy: A preliminary cadaveric study
    (2016-08-01T00:00:00Z) Elmadag, Mehmet; Uzer, GÖKÇER; Yildiz, FATİH; CEYLAN, Hasan H.; Acar, Mehmet A.; ELMADAĞ, NUH MEHMET; UZER, GÖKÇER; YILDIZ, FATİH
    Objective: The aim of this cadaveric study was to investigate the efficacy of the modified Stoppa approach in Ganz periacetabular osteotomy (PAO). Methods: The Ganz PAO was performed on 10 hemipelvises with normal hips, from 5 cadavers using the modified Stoppa approach through the Pfannenstiel incision. All of the osteotomies were performed under fluoroscopic control and direct visualizing the osteotomy site from the same incision. After the osteotomy, the acetabulum was medialized and redirected anterolaterally, and fixed with 2 screws. The neurovascular structures and the joints were examined by dissecting the soft tissues after fixation of the osteotomies. Outcome parameters were center-edge (CE) angle, the distances between the osteotomy and anterior superior iliac spine (ASIS), and between the osteotomy and the sciatic notch, neurovascular and joint penetrations. Results: After the osteotomy, the mean CE angle was improved from 19.8 degrees to 25.2 degrees, mean distance between the osteotomy and ASIS was 3.1 cm, and the mean distance between the osteotomy and the sciatic notch was 10.2 mm. The neurovascular structures and the joints were examined by dissecting the soft tissues after fixation of the osteotomies. No damage to the joint, surrounding arteries, veins or nerves was detected in any of the cadavers. Conclusions: Bilateral dysplastic hips can be treated with a 10 cm, cosmetically more acceptable incision in the same session using this approach. Quadrilateral surface of the acetabulum can be directly seen using this approach and the osteotomy can be safely performed. (C) 2016 Turkish Association of Orthopaedics and Traumatology. Publishing services by Elsevier B.V.
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    PublicationOpen Access
    Cytotoxicity of a new antimicrobial coating for surgical screws: an in vivo study
    (2017-01-01) Guzel, Yunus; Elmadag, Mehmet; Uzer, GÖKÇER; Yildiz, FATİH; Bilsel, Kerem; Tuncay, Ibrahim; ELMADAĞ, NUH MEHMET; UZER, GÖKÇER; YILDIZ, FATİH; BİLSEL, İSMAIL KEREM; TUNCAY, İBRAHİM
    he risk of surgery-related infection is a persistent problem in orthopaedics and infections involving implants are particularly difficult to treat. This study explored the responses of bone and soft tissue to antimicrobialcoated screws. We investigated whether such screws, which have never been used to fix bony tissues, would result in a cytotoxic effect. We hypothesised that the coated screws would not be toxic to the bone and that the likelihood of infection would be reduced since bacteria are not able to grow on these screws. METHODS Titanium screws were inserted into the left supracondylar femoral regions of 16 rabbits. The screws were either uncoated (control group, n = 8) or coated with a polyvinylpyrrolidone-polyurethane interpolymer with tertiary amine functional groups (experimental group, n = 8). At Week 6, histological samples were obtained and examined. The presence of necrosis, fibrosis and inflammation in the bony tissue and the tissue surrounding the screws was recorded. RESULTS Live, cellular bone marrow was present in all the rabbits from the experimental group, but was replaced with connective tissue in four rabbits from the control group. Eight rabbits from the control group and two rabbits from the experimental group had necrosis in fatty bone marrow. Inflammation was observed in one rabbit from the experimental group and five rabbits from the control group. CONCLUSION Titanium surgical screws coated with polyvinylpyrrolidone-polyurethane interpolymer were associated with less necrosis than standard uncoated screws. The coated screws were also not associated with any cytotoxic side effect.