Person: CENGİZ, FATMA PELIN
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Publication Dermatolojik Hastalıklarda Çinko-nun Önemi(2016-04-01) EMİROĞLU, NAZAN; Cengiz, FATMA PELİN; EMİROĞLU, NAZAN; CENGİZ, FATMA PELINPublication The relation between dermoscopy and histopathology of basal cell carcinoma(2015-05-01) Emiroglu, NAZAN; Cengiz, FATMA PELİN; KEMERIZ, Funda; EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN: Basal cell carcinoma is the most frequent cancer in fair-skinned populations and dermoscopy is an important, non-invasive technique that aids in the diagnosis of Basal cell carcinoma. OBJECTIVES: The aim of this study was to evaluate the relationship between histopathological subtypes and dermoscopic features of Basal cell carcinoma. METHODS: This study included 98 patients with clinically and histopathologically confi rmed Basal cell carcinomas. The dermoscopic features of the lesions from each patient were analyzed before the histopathological fi ndings were evaluated. RESULTS: Dermoscopic structures were observed in all 98 patients and irregular vascularity was identifi ed in 78 patients (79.6%). The most common vascular pattern was the presence of arborizing vessels (42 patients, 42.9%) followed by arborizing microvessels (21 patients, 21.4%) and short fi ne telangiectasias (SFTs; 15 patients, 15.3%). White streaks (38 patients, 38.8%), translucency (31 patients, 31.6%), a milky-pink to red background (42 patients, 42.9%), and erosion/ulceration (29 patients, 29.6%) were also observed. Pigmented islands were seen as blue-gray globules (7 patients, 7.1%) and blue-gray ovoid nests (42 patients, 42.9%). The pigment distribution pattern was maple leaf-like areas in 9 patients (9.2 %) and spoke wheel-like areas in 6 patients (6.1%). CONCLUSIONS: Basal cell carcinomas show a wide spectrum of dermoscopic features. Arborizing vessels were the most common dermoscopic fi ndings in Basal cell carcinomas, while superfi cial Basal cell carcinomas displayed mainly milky-pink to red areas, and arborizing microvessels. The most common dermoscopic features of pigmented types were islands of pigment (blue-gray globules, blue-gray ovoid nests). In conclusion, dermoscopy can be used as a valuable tool for the diagnosis of Basal cell carcinomas and prediction of their histopathological subtypes. Keywords: Carcinoma, basal cell; Dermoscopy; Neoplasms, basal cellPublication Serum visfatin levels in Behcet-s disease(2015-01-01T00:00:00Z) EMİROĞLU, Nazan; CENGİZ, Fatma Pelin; EMİROĞLU, NAZAN; CENGİZ, FATMA PELINBackground and Design: The genetic predisposition, infectious agents, various antibodies and oxidative stress has been suggested to be among the possible causes of the etiopathogenesis of Behcet-s disease (BD). Recently, a new protein called visfatin, synthesized by adipose tissue has been identified. Visfatin has been found to be associated with many cases like insulin resistance, obesity, atherosclerosis, inflammation, immunity. In this study, we aimed to evaluate the relationship between serum visfatin levels and the activity of Behcet-s disease, and determine the role of visfatin in the inflammatory process of BD.Publication Dermoscopic and clinical features of pigmented skin lesions of the genital area.(2015-03-01T00:00:00Z) Cengiz, FATMA PELİN; EMIROGLU, NAZAN; WELLENHOF, RH; CENGİZ, FATMA PELIN; EMİROĞLU, NAZANPublication Doksisiklin Tedavisine Yanıt Veren Prurigo Pigmentoza Olgusu(2015-07-01T00:00:00Z) KEMERİZ, FUNDA; EMİROĞLU, NAZAN; CENGİZ, FATMA PELİN; ATACAN, DAMLA; EMİROĞLU, NAZAN; CENGİZ, FATMA PELINPublication Sex hormones in male psoriasis patients and their correlation with the Psoriasis Area and Severity Index.(2015-05-01T00:00:00Z) CEMIL, BC; Cengiz, FATMA PELİN; ATAS, H; OZTURK, G; CANPOLAT, F; CENGİZ, FATMA PELINPublication Verrucous Bowen’s disease on groin with dermoscopic and siascopic images(2017-05-06T00:00:00Z) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDEPublication The HLA-Cw12 Allele Is an Important Susceptibility Allele for Psoriasis and Is Associated with Resistant Psoriasis in the Turkish Population(2019-01-01T00:00:00Z) ONSUN, NAHİDE; Pirmit, Serpil; Ozkaya, Dilek; Çelik, Şirin; Rezvani, Aylin; CENGİZ, Fatma Pelin; Kekik, Cigdem; ONSUN, NAHIDE; REZVANİ, AYLİN; CENGİZ, FATMA PELINBackground. Psoriasis is a multifactorial immune-mediated infammatory disease triggered by both genetic and environmental factors. Te strong association between psoriasis and HLA-C∗06 allele has been demonstrated in various races. Te HLAC∗12 allele is closely related to the HLA-C∗06 family of alleles and shares identical sequences. To the best of our knowledge, there is no information about the relationship between HLA-C∗12 and psoriasis in the Turkish population. Te present study aims to determine this relationship. Methods. Tis case control study involved 150 patients with plaque-type psoriasis and 145 age- and gender-matched healthy individuals. Severity of psoriasis was measured using the PASI scores of all patients and joint involvement was investigated with CASPAR criteria. HLA-C alleles were determined with a Tepnel-Lifecodes system. Results. HLA-C∗06, HLA-C∗12, and HLA-C∗04 alleles were most commonly observed in psoriasis patients. HLA-C∗06 and HLA-C∗12 were signifcantly more frequent in the psoriasis group. HLA-C∗06 was 4.11 times more common in psoriasis patients. An increase in PASI (Psoriasis Area Severity Index) scores was compatible with HLA-C∗12 positivity. A need for systemic treatment was highly noticeable in patients with the HLA-C∗12 allele. Conclusions. HLA-C∗12 was found as the second most frequent allele with psoriasis in Turkish population and was associated with severe psoriasis. Our study is limited as we could not investigate other potentially related alleles other than HLA-C alleles and risk factors increasing severity of psoriasis.Publication Verrucous Bowen’s disease on groin with dermoscopic and siascopic images(2017-05-06T00:00:00Z) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDEPublication Hafif ve Orta Şiddetli Akne Hastalarında A ve E Vitamini Düzeyleri(2017-04-01T00:00:00Z) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE