Person: ŞENTÜRK, HAKAN
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Publication Metadata only Human In Vitro Disease Models: Dawning a New Era Away from Animal Models(2016-09-01T00:00:00Z) Senturk, HAKAN; ŞENTÜRK, HAKANPublication Metadata only Role of Serum and Biliary CEA, CA19-9, VEGFR-3 and TAC for Differentation of Malignant and Benign Biliary Obstruction(2014-05-01) Ince, ALİ TÜZÜN; YILDIZ, Kemal; BAYSAL, Birol; DANALIOGLU, Ahmet; KOCAMAN, Orhan; TOZLU, Mukaddes; GANGARAPU, Venkatanarayana; KEMIK, Ahu Sarbay; UYSAL, Oemer; Senturk, HAKAN; İNCE, ALİ TÜZÜN; UYSAL, ÖMER; ŞENTÜRK, HAKANPublication Metadata only PRESENCE OF ONLY WILDTYPE VIRUS IS THE STRONGEST DETERMINANT OF HBVDNA UNDETECTABILITY AND HBSAG CLEARANCE IN HBEAG-POSITIVE CHRONIC HEPATITIS B PATIENTS TREATED WITH PEGINTERFERON(2012-04-01T00:00:00Z) Sonneveld, M. J.; Rijckborst, V.; Zeuzem, S.; Heathcote, E. J.; Simon, K.; ŞENTÜRK, HAKAN; Pas, S. D.; Hansen, B. E.; Janssen, H. L.; ŞENTÜRK, HAKANPublication Metadata only Sa1359 – Cholecystitis in Pancreatic Carcinoma: A Poorly Recognized Condition with High Rate of Sepsis Related Mortality Cholecystitis in Pancreatic Carcinoma: A Poorly Recognized Condition with High Rate of Sepsis Related Mortality.(2019-05-28T00:00:00Z) Koçhan, Koray; ŞENTÜRK, HAKAN; KÖKER, İBRAHİM HAKKI; BİBERCİ KESKİN, ELMAS; İNCE, ALİ TÜZÜN; BAŞARANOĞLU, METİN; ŞENTÜRK, HAKAN; KÖKER, İBRAHİM HAKKI; KOÇHAN, KORAY; BİBERCİ KESKİN, ELMAS; İNCE, ALİ TÜZÜN; BAŞARANOĞLU, METİNPublication Metadata only Pankreas Adenokarsinomu ve Tümör Çevresi Pankreas Doku Örneklerinde Helicobacter Pylori Sesifik DNA Varlığının Araştırılması 12 Ulusal Hepato Gastroenteroloji Kongresi Afyon(2015-10-11T00:00:00Z) BAYSAL, BİROL; Gültepe, B; İNCE, ALİ TÜZÜN; Gültepe, İ; KAYAR, YUSUF; Erdem, Emrullah; BAŞARANOĞLU, METİN; DANALIOĞLU, AHMET; ŞENTÜRK, HAKAN; İNCE, ALİ TÜZÜN; BAŞARANOĞLU, METİN; ŞENTÜRK, HAKANPublication Metadata only The evaluation of cellular and humoral immunity characteristics in gastrointestinal and hepatocellular cancers(2014-06-25T00:00:00Z) TÜRKDOĞAN, MEHMET KÜRŞAT; KIZILTAN, HÜRİYE ŞENAY; GÜNEŞ BAYIR, AYŞE; KAYAR, YUSUF; ŞENTÜRK, HAKAN; İNCE, ALİ TÜZÜN; KOCAMAN, ORHAN; Danalıoğlu, Ahmed; KIZILTAN, HURİYE ŞENAY; GÜNEŞ BAYIR, AYŞE; ŞENTÜRK, HAKAN; İNCE, ALİ TÜZÜNPublication Metadata only The Effect of Helicobacter pylori Infection on the Development of Splenic Vein Thrombosis in Chronic Pancreatitis Patients(2012-05-01T00:00:00Z) Sisman, Gurhan; Erzin, Yusuf; Senturk, HAKAN; ŞENTÜRK, HAKANPublication Metadata only Applying Artificial Neural Networks on Two-Layer Semantic Trajectories for Predicting the Next Semantic Location(2017-01-01T00:00:00Z) Karatzoglou, Antonios; Sentuerk, HAKAN; Jablonski, Adrian; Beigl, Michael; ŞENTÜRK, HAKANLocation-awareness and prediction play a steadily increasing role as systems and services become more intelligent. At the same time semantics gain in importance in geolocation application. In this work, we investigate the use of artificial neural networks (ANNs) in the field of semantic location prediction. We evaluate three different ANN types: FFNN, RNN and LSTM on two different data sets on two different semantic levels each. In addition we compare each of them to a Markov model predictor. We show that neural networks perform overall well, with LSTM achieving the highest average score of 76,1%.Publication Metadata only Preliminary Results of Pigtail Plastic Stent (PPS) and Fully Covered Self Expandable Metallic Stent (FCSEMS) Placement in the Endoscopic Treatment of Pancreatic Fluid Collections(2013-05-01T00:00:00Z) Senturk, Hakan; Kocaman, Orhan; Baysal, Birol; Ince, ALİ TÜZÜN; Danalioglu, Ahmet; Tozlu, Mukaddes; Kocakoc, Ercan; ŞENTÜRK, HAKAN; İNCE, ALİ TÜZÜNPublication Metadata only Is alanine aminotransferase level a surrogate biomarker of hepatic apoptosis in nonalcoholic fatty liver disease?(2010-04-01T00:00:00Z) Canbakan, Billar; Senturk, HAKAN; Canbakan, Mustafa; TOPTAŞ, TAYFUR; Tabak, Omur; Balci, Hurtye; OLGAÇ, Necat Vakur; Ozbay, Guisen; ŞENTÜRK, HAKANAim: To evaluate the serum alanine aminotransferase (ALT) variabilities in nonalcoholic fatty liver disease (NAFLD) and correlate it with hepatocyte apoptosis and oxidative stress parameters. Methods: 24 patients with NAFLD and normal ALT were compared with 26 subjects with NAFLD and elevated ALT. Liver oxidative stress was estimated on the basis of malondialdehyde, superoxide dismutase and glutathione. Immunohistochemistry was performed for activated caspase 3 and 8, nuclear factor-kappa B, antiapoptotic Bcl-2 protein and serum TNF receptor levels were measured. Results: The mean caspase 3 and 8 activity scores, oxidative stress parameters, necroinflammatory grade and prevalence of severe fibrosis were comparable across the groups with normal versus elevated ALT. Patients with nonalcoholic steatohepatitis had significantly higher caspase 3 and 8 activity (percentage of cells with positive staining per high power field), and serum malondialdehyde (mmol/l) levels than those with simple steatosis. ALT elevation was not a risk factor for advanced necroinflammatory grade and fibrosis. A receiver operating characteristic curve did not demonstrate sensitivity and specificity for discriminative power of ALT. Conclusion: Apoptosis and oxidative stress are the main processes contributing to disease progression in NAFLD. ALT values do not correlate with the parameters of apoptosis and oxidative stress. The disease severity can only be determined by liver biopsy.