Person: OGUN, HAMZA
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Publication Open Access Research Burden of Interstitial Lung Diseases in Turkey - RBILD(2022-01-01T00:00:00Z) AYÇİÇEK, OLCAY; Cetinkaya, Erdogan; Ucsular, Fatma Demirci; BAYRAM, NAZAN; Senyigit, Abdurrahman; Aksel, Nimet; ATİLLA, NURHAN; Sarioglu, Nurhan; Niksarlioglu, Elif Yelda; Ilgazli, Ahmet; KILIÇ, TALAT; Günbatar, Hülya; Cilekar, Sule; EKİCİ, AYDANUR; Arinc, Sibel; Bircan, Haci Ahmet; Duman, Dildar; Dikis, Ozlem Sengoren; YAZICI, ONUR; Kansu, Abdulla; TUTAR, NURİ; Ozsari, Emine; BERK, SERDAR; Varol, Yelda; Erbaycu, Ahmet Emin; SERTOĞULLARINDAN, BÜNYAMİN; Cirak, Ali Kadri; Cortuk, Mustafa; Karadeniz, Gulistan; Simsek, Alper; SEZGİ, CENGİZHAN; EREL, FUAT; Ciftci, Tuba; Sünnetçioğlu, Aysel; EKİCİ, MEHMET SAVAŞ; Agca, Meltem; Ozturk, Onder; OGUN, HAMZA; Acar, Elif; Alizoroglu, Dursun; Gezer, Esma; ÖZLÜ, TEVFİK; BİRCAN, HACI AHMET; OGUN, HAMZAIntroduction: The aim of our study is to investigate the etiological distribution of ILD in Turkey by stratifying the epidemiological characteristics of ILD cases, and the direct cost of initial diagnosis of the diag-nosed patients. Material-Method: The study was conducted as a multicenter, prospective, cross-sectional, clinical observation study. Patients over the age of 18 and who accepted to participate to the study were included and evaluated as considered to be ILD. The findings of diagnosis, examination and treatment carried out by the cent-ers in accordance with routine diagnostic procedures were recorded observationally. Results: In total,1070 patients were included in this study. 567 (53%) of the patients were male and 503 (47%) were female. The most frequently diagnosed disease was IPF (30.5%). Dyspnea (75.9%) was the highest incidence among the presenting symptoms. Physical examination found bibasilar inspiratory crackles in 56.2 % and radiological findings included reticular opacities and interlobular septal thickenings in 55.9 % of the cases. It was observed that clinical and radiological findings were used most frequently (74.9%) as a diagnostic tool. While the most common treatment approaches were the use of systemic steroids and antifibrotic drugs with a rate of 30.7% and 85.6%, respectively. The total median cost from the patient-s admission to diagnosis was 540 Turkish Lira. Conclusion: We believe that our findings compared with data from other countries will be useful in showing the current situation of ILD in our country to discuss this problem and making plans for a solution.Publication Metadata only Covid-19 Hastalarının Tedavilere Uyumu(2022-03-19) Akkoyun M.; Ogun H.; Akkoyunlu Y.; OGUN, HAMZA; AKKOYUNLU, YASEMİNPublication Metadata only Is short-course therapy enough at drug-resistant tuberculosis?(2018-01-01T00:00:00Z) OGUN, HAMZA; Ozmen, Ipek; Ozari Yildirim, Elif; Torun, Tulay; Calisir, Haluk Celalettin; OGUN, HAMZAIntroduction: Tuberculosis drug resistance can be assessed by physicians with different approaches on issues such as the choice of treatment protocol and duration of treatment.Publication Metadata only The Effects of Polypharmacy, Nutritional and Functional Status on the Progression of COVID-19 in Older Adults(2021-08-01T00:00:00Z) Ogun, Hamza; Akkoyunlu, Yasemin; Durdu, Bülent; Okyaltırık, Fatmanur; Kazancıoğlu, Rümeyza; Meriç Koç, Meliha; Gülen, Bedia; Sümbül, Bilge; Okay, Gülay; Bolukcu, Sibel; Sönmez, Ertan; Kaçmaz, Asiye Bahar; Soysal, Pınar; Tan, Semen Gökçe; SOYSAL, PINAR; DURDU, BÜLENT; AKKOYUNLU, YASEMİN; OGUN, HAMZA; OKYALTIRIK, FATMANUR; OKAY, GÜLAY; SÜMBÜL, BİLGE; SÖNMEZ, ERTAN; MERİÇ KOÇ, MELİHA; KAZANCIOĞLU, RÜMEYZAPublication Metadata only Mesleki Enfeksiyon Hastalıkları(2019-08-01T00:00:00Z) Ogun, Hamza; Akkoyunlu, Yasemin; OGUN, HAMZA; AKKOYUNLU, YASEMİNPublication Metadata only Thorax computed tomography findings and anti-SARS-CoV-2 immunoglobulin G levels in polymerase chain reaction-negative probable COVID-19 cases.(2022-11-25) Yurtsever I.; Karatoprak C.; Sumbul B.; Kiskac M.; Tunc M.; Zorlu M.; Ogun H.; Durdu B.; Toluk O.; Cakirca M.; YURTSEVER, İSMAİL; KARATOPRAK, CUMALİ; SÜMBÜL, BİLGE; KISKAÇ, MUHARREM; TUNÇ, MUHAMMED; ZORLU, MEHMET; OGUN, HAMZA; DURDU, BÜLENT; TOLUK, ÖZLEM; ÇAKIRCA, MUSTAFAOBJECTIVE: This study aimed to evaluate the SARS-CoV-2 immunoglobulin G (IgG) levels after 6 months of polymerase chain reaction (PCR) negativebut assumed to be COVID-19 positive cases to investigate the relationship between IgG levels and thoracic computed tomography (CT) findings.METHODS: This was a single-center study that included patients whose PCR test results were negative at least three times using nasopharyngealswabs but had clinical findings of COVID-19 and thoracic CT findings compatible with viral pneumonia. Six months after discharge, the IgG antibodieswere analyzed. The cutoff value for negative and positive serology was defined as <1.4 (index S/C) and ≥1.4 (index S/C), respectively. In addition, thepatients were categorized according to their thoracic CT findings as high (typical) and low (atypical). Also, the patients were grouped into classes as<5% lung involvement versus ≥5% lung involvement.RESULTS: The patients’ mean age was 49.78±12.96 years. PCR was negative, but patients with COVID-19 symptoms who had SARS-CoV-2 IgGpositive were 81.9% (n=95). The antibody titer and lung involvement ≥5% were statistically significantly higher in SARS-CoV-2 IgG positive cases(p<0.001 and p=0.021). Age and chest CT findings were the risk factors for lung involvement (OR=1.08, p<0.001 and OR=2.19, p=0.010, respectively).CONCLUSION: This study is valuable because increasing severity (≥5%) of lung involvement appears to be associated with high and persistent IgGantibody titers. In probable cases of COVID-19, even if the PCR test is negative, high IgG titers 6 months after discharge can predict the rate of lungparenchymal involvement.