Person: DOĞAN, REMZI
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Publication Metadata only Percutaneous Adjustable Closed Otoplasty for Prominent Ear Deformity(2013-03-01) Ozturan, ORHAN; Dogan, REMZİ; Eren, SABRİ BAKİ; AKSOY, Fadlullah; VEYSELLER, Bayram; ÖZTURAN, ORHAN; DOĞAN, REMZI; EREN, SABRİ BAKİ; AKSOY, FADLULLAHObjective: The aim of this study is to follow longitudinally the prominent ears treated by percutaneous adjustable closed otoplasty (PACO) and evaluate this procedure in terms of technical efficiency, recurrence, complications, and patient satisfaction.Publication Metadata only Audiological findings in pediatric perineal allergic rhinitis (house dust mite allergy) patients(2014-05-01) AKSOY, Fadlullah; Nursoy, MUSTAFA ATİLLA; Dogan, REMZİ; Ozturan, ORHAN; Eren, SABRİ BAKİ; VEYSELLER, Bayram; Ozkaya, EMİN; DEMIR, Aysegul Dogan; OZTURK, Burak; NURSOY, MUSTAFA ATİLLA; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN; EREN, SABRİ BAKİ; ÖZKAYA, EMİNAllergic rhinitis is the type 1 hypersensitivity reaction of the nasal mucosa and its primary mediator is Ig E. It is most frequently observed in children and adolescents. Our purpose in this study is to investigate the impact of allergy on hearing functions in children with perineal allergic rhinitis (house dust mite allergy). 50 perineal allergic rhinitis (house dust mite allergy) patients (33 male, 17 female patients, aged between 6 and 15, average age 10.4) and 20 control patients (12 male, 8 female, aged between 6 and 15, average age 11.2) underwent high frequency pure tone audiometry, acoustic reflex, otacoustic emission (OAE) and auditory brainstem potentials to assess their auditory functions. No statistically significant difference was detected between the study group and the control group with respect to their hearing thresholds (250-16,000 Hz). No statistically significant difference was detected as a result of the comparison between the study group and control group in terms of their signal-noise ratios at Distortion Product OAE in all frequencies (996-8,004 Hz). No statistically significant difference was detected between the study group and the control group in terms of the 1st, 3rd and 5th wave latencies and 1-3, 3-5 and 1-5 inter-peak values. This study is the first study where the audiological functions of the pediatric perineal allergic rhinitis (house dust mite allergy) patients were assessed. No significant difference was detected between the group of pediatric perineal allergic rhinitis (house dust mite allergy) patients and the control group with respect to their audiological functions.Publication Metadata only Olfactory function and nasal manifestations of Behcet-s disease(2014-04-01) VEYSELLER, Bayram; Dogan, REMZİ; SU, Ozlem; AKSOY, Fadlullah; MERIC, Aysenur; Ozturan, ORHAN; DOĞAN, REMZI; AKSOY, FADLULLAH; SU KÜÇÜK, ÖZLEM; ÖZTURAN, ORHANObjective: To investigate the effect of Behcet-s disease on olfactory function, the nasal mucosa, and nasal symptoms.Publication Metadata only Protective effect of trimetazidine on amikacin-induced ototoxicity in rats(2014-04-01) AKSOY, Fadlullah; Dogan, REMZİ; Ozturan, ORHAN; VEYSELLER, Bayram; PEKTAS, Alev; HUSEYINBAS, Onder; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN; EREN, SABRİ BAKİObjective: Aminoglycoside antibiotics are known to have ototoxic effects and may induce sensorineural hearing loss. This study investigated the protective effect of trimetazidine, which has antioxidant and cytoprotective properties, against amikacin ototoxicity.Publication Metadata only Cartilage-Sparing Techniques Versus Percutaneous Adjustable Closed Otoplasty for Prominent Ear Deformity(2014-05-01) Ozturan, ORHAN; Dogan, REMZİ; Eren, SABRİ BAKİ; AKSOY, Fadlullah; VEYSELLER, Bayram; ÖZTURAN, ORHAN; DOĞAN, REMZI; EREN, SABRİ BAKİ; AKSOY, FADLULLAHObjective: The goal of this study is to follow longitudinally the prominent ears treated by either cartilage-sparing techniques (CSTs) or percutaneous adjustable closed otoplasty (PACO) and compare them as to efficacy, reoccurrence, complications, and patient contentedness.Publication Metadata only Betahistine Exacerbates Amikacin Ototoxicity(2015-04-01) AKSOY, Fadlullah; Dogan, REMZİ; Ozturan, ORHAN; Yildirim, YAVUZ SELİM; VEYSELLER, Bayram; Yenigun, ALPER; OZTURK, Burak; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN; YILDIRIM, YAVUZ SELİM; YENİGÜN, ALPERObjective: Betahistine augments cochlear blood flow and is currently used as an efficient therapeutic agent. Amikacin is used in a wide range of areas, but its ototoxic effect continues to be problematic. This study investigates the effect of betahistine on amikacin-induced ototoxicity.Publication Metadata only Hyperbaric oxygen therapy of olfactory dysfunction in diabetic neuropathy with type 2 diabetes mellitus and a new definition -diabetic olfactopathy-(2016-01-01) Dogan, ELİF ECE; Veyseller, Bayram; DOĞAN, REMZİ; AKSOY, Fadlullah; ÖZTURAN, ORHAN; TUGRUL, Selahattin; YENİGÜN, ALPER; DOĞAN, REMZI; YENİGÜN, ALPER; AKSOY, FADLULLAH; DOĞAN, ELİF ECE; ÖZTURAN, ORHANPublication Metadata only Effect of nasal antihistamine on secretory IgA in nasal lavage of rats(2018-01-01) Dogan, REMZİ; AKSOY, Fadlullah; Goktas, Seda Sezen; Kocak, Ilker; Yildirim, YAVUZ SELİM; Incir, Said; Ozturan, ORHAN; DOĞAN, REMZI; AKSOY, FADLULLAH; YILDIRIM, YAVUZ SELİM; ÖZTURAN, ORHANThe humoral IgA is an immunoglobulin which plays a defensive role for organisms on mucosal surfaces. Today, intranasal antihistamines are effectively used in the treatment of allergic rhinitis. In our study, the effect of azelastine hydrochloride-a nasal antihistaminic-on humoral IgA of the nasal mucosa has been reviewed empirically. Twenty-four female Sprague-Dawley rats were included in our study. The rats were divided into three groups randomly. Group 1(azelastine hydrochloride): rats in this group had nasal azelastine hydrochloride (0.05%) applied for 30 days at 10 A mu l/nostril dosage. Group 2 (saline): saline (0.09%) was applied to the rats in this group for 30 days at 10 A mu l/nostril dosage. Group 3 (control): no application was made throughout the study. The chemicals applied in Groups 1 and 2 were applied to both nostrils by mounting a flexible micropipette to the end of an insulin injector. At the beginning of the study, nasal lavage was performed to both nostrils of the rats in every group on the 15th and 30th day to aspirate irrigation solution (distilled water). The aspirated liquids were kept at - 80A degrees temperature and reviewed together at the end of study. Within-group comparisons: in Group 1 (azelastine hydrochloride), the humoral IgA value on the 15th day was significantly higher than the basal value (p = 0.037). There is a significant difference between humoral IgA value on the 30th day and humoral IgA value on the 15th day (p = 0.045). In Group 2 (saline), no significant difference is available between basal, 15th day and 30th day humoral IgA values (p = 0.265). In Group 3 (control), no significant difference is available between basal, 15th day and 30th day humoral IgA values (p = 0.374). Between-group comparison: there is no significant difference in between-group humoral IgA basal values (p = 0.714). On days 15 and 30, Humoral IgA value of Group 1 was significantly higher than that of Groups 2 and 3 (p = 0.013, p = 0.024, respectively). According to the results we achieved in our study, nasal antihistaminic (azelastine hydrochloride) significantly increases the level of humoral IgA. Our study is the first one in the literature to reveal a relation between nasal antihistaminic and humoral IgA and there is a further need for clinical, randomized and prospective studies.Publication Metadata only Effect of a combination of mometasone furoate, levofloxacin, and retinyl palmitate with an in situ gel-forming nasal delivery system on nasal mucosa damage repair in an experimental rabbit model(2017-12-01) AKSOY, Fadlullah; DOĞAN, REMZİ; ÖZTURAN, ORHAN; ALTUNTAŞ, Ebru; YENER, FATMA GÜLGÜN; TOPÇU, GÜLAÇTI; GÜLER, BERİL; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN; TOPÇU, GÜLAÇTI; GÜLER, BERILPublication Metadata only Effect of Nasal Corticosteroid on Secretory Immunoglobulin A Measured in Rat Nasal Lavage: Experimental Study(2015-08-01) AKSOY, Fadlullah; Dogan, REMZİ; Kocak, Ilker; VEYSELLER, Bayram; Ozturan, ORHAN; Incir, Said; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHANObjective In this study, we aimed to experimentally investigate the effects of nasal corticosteroids on the levels of secretory immunoglobulin A (sIgA) in nasal mucosa in rats.