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ONSUN, NAHIDE

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NAHIDE
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ONSUN
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2016 - 202027
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Author: ONSUN, NAHİDE × Author: CENGİZ, FATMA PELIN ×

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Now showing 1 - 10 of 27
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    PublicationOpen Access
    The HLA-Cw12 Allele Is an Important Susceptibility Allele for Psoriasis and Is Associated with Resistant Psoriasis in the Turkish Population
    (2019-01-01T00:00:00Z) ONSUN, NAHİDE; Pirmit, Serpil; Ozkaya, Dilek; Çelik, Şirin; Rezvani, Aylin; CENGİZ, Fatma Pelin; Kekik, Cigdem; ONSUN, NAHIDE; REZVANİ, AYLİN; CENGİZ, FATMA PELIN
    Background. Psoriasis is a multifactorial immune-mediated infammatory disease triggered by both genetic and environmental factors. Te strong association between psoriasis and HLA-C∗06 allele has been demonstrated in various races. Te HLAC∗12 allele is closely related to the HLA-C∗06 family of alleles and shares identical sequences. To the best of our knowledge, there is no information about the relationship between HLA-C∗12 and psoriasis in the Turkish population. Te present study aims to determine this relationship. Methods. Tis case control study involved 150 patients with plaque-type psoriasis and 145 age- and gender-matched healthy individuals. Severity of psoriasis was measured using the PASI scores of all patients and joint involvement was investigated with CASPAR criteria. HLA-C alleles were determined with a Tepnel-Lifecodes system. Results. HLA-C∗06, HLA-C∗12, and HLA-C∗04 alleles were most commonly observed in psoriasis patients. HLA-C∗06 and HLA-C∗12 were signifcantly more frequent in the psoriasis group. HLA-C∗06 was 4.11 times more common in psoriasis patients. An increase in PASI (Psoriasis Area Severity Index) scores was compatible with HLA-C∗12 positivity. A need for systemic treatment was highly noticeable in patients with the HLA-C∗12 allele. Conclusions. HLA-C∗12 was found as the second most frequent allele with psoriasis in Turkish population and was associated with severe psoriasis. Our study is limited as we could not investigate other potentially related alleles other than HLA-C alleles and risk factors increasing severity of psoriasis.
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    Verrucous Bowen’s disease on groin with dermoscopic and siascopic images
    (2017-05-06T00:00:00Z) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
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    Verrucous Bowen’s disease on groin with dermoscopic and siascopic images
    (2017-05-06T00:00:00Z) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
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    PublicationOpen Access
    Frequency and risk factors for secondary malignancies in patients with mycosis fungoides
    (2016-08-01) EMIROGLU, NAZAN; CENGIZ, F. P.; BAHALI, A. Gulsel; Su, O.; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
    Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma (CTCL), has an incidence of 6.4 per million people [1]. Patients with CTCL have an increased risk of the development of secondary malignancies, particularly lymphomas [2,3]. We conducted a 20-year population-based cohort study to assess the risk factors of secondary cancers in MF patients from our center.
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    Hafif ve Orta Şiddetli Akne Hastalarında A ve E Vitamini Düzeyleri
    (2017-04-01T00:00:00Z) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
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    Alopesi areatanın patogenezinde dehidroepiandrosteron sülfatın yeri
    (2017-04-15T00:00:00Z) EMİROĞLU, NAZAN; CENGİZ, FATMA PELİN; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
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    ALOPESİ AREATANIN PATOGENEZİNDE DEHİDROEPİANDROSTERON SÜLFATIN YERİ
    (2017-04-15T00:00:00Z) EMİROĞLU, NAZAN; CENGİZ, FATMA PELİN; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
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    Akneli Adolesanlarda Kardiyolojik Risk Faktörleri
    (2017-05-14T00:00:00Z) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; BIYIK ÖZKAYA, DİLEK; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE
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    Adult Langerhans Cell Histiocytosis with Recurrent Vulvar Ulcers
    (2020-01-01T00:00:00Z) EMİROGLU, NAZAN; DİZMAN, DİDEM; CENGİZ, FATMA PELİN; GEÇER, MELİN; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; GEÇER, MELİN; ONSUN, NAHIDE
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    Malignant melanoma arising in congenital melanocytic nevi: clinical and dermoscopic challenges
    (2017-01-01T00:00:00Z) CENGİZ, FATMA PELİN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM SU; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDE