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ULUGANYAN, MAHMUT

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MAHMUT
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ULUGANYAN
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Subject: Major adverse cardiac events × Subject: Estimated glomerular filtration rate ×

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    PublicationOpen Access
    The Impact of Admission Serum Creatinine Derived Estimated Glomerular Filtration Rate on Major Adverse Cardiac Events in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
    (2016-04-01) ULUGANYAN, MAHMUT; KARACA, GÜRKAN; ULUTAŞ, TÜRKER KEMAL; EKMEKÇİ, AHMET; BAKSHALİYEV, NİJAD; MURAT, AHMET; KÖROĞLU, BAYRAM; UYAREL, HÜSEYİN; EREN, MEHMET; ULUGANYAN, MAHMUT; BAKHSALIYEV, NIJAD
    Background: The impact of Cockroft-Gault (C-G) derived estimated glomerular filtration rate (eGFR) on mortality and major adverse cardiac events (MACEs) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) was assessed. Methods: A total of 884 patients were classified into four categories according to admission creatine derived eGFR: < 60, 60 - < 90, 90 - < 120, and ≥ 120 mL/min/1.73 m(2). Results: In-hospital and long-term MACEs were significantly higher in eGFR < 60 mL/min/1.73 m(2) subgroup (P < 0.001 and P = 0.028). Multivariate analysis demonstrated 7.78-fold (95% CI: 0.91 - 66.8) higher mortality risk in eGFR < 60 mL/min/1.73 m(2) subgroup. Conclusion: As an easily applicable bedside method, C-G derived eGFR could be important for prediction of in-hospital and long-term mortality and MACE in STEMI patients undergoing primary PCI.