Person: ULUGANYAN, MAHMUT
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Publication Metadata only Stress-induced transient midventricular ballooning: a new variant of broken heart syndrome(2013-02-01) Uluganyan, MAHMUT; Velibey, Yalcin; Calik, Nazmi; Orhan, Ahmet; Karaca, Gurkan; Tayyareci, Gulsah; ULUGANYAN, MAHMUTA 72-year-old female patient admitted to the emergency department with substernal chest pain due to vigorous emotional stress. Her electrocardiogram revealed negative T waves in DI, aVL, and V-1 to V-3 derivations, and she had an elevated troponin level. Cardiac catheterization was performed and showed angiographically normal epicardial coronary arteries. The left ventriculogram demonstrated midventricular dilatation and akinesis with a hypercontractile apex and base. We report a case of new variant of broken heart syndrome in which only the midventricle is affected.Publication Metadata only EKOKARDİYOGRAFİ LABORATUARINDA TORASİK AORT ANEVRİZMASININ TESPİTİ VE İLİŞKİLİ DURUMLAR(2018-11-01T00:00:00Z) Uluganyan, Mahmut; ULUGANYAN, MAHMUTPublication Metadata only The Predictive Value of PRECISE-DAPT Score for In-Hospital Mortality in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention(2019-05-01) Tanik, Veysel Ozan; Cinar, Tufan; Arugaslan, Emre; Karabag, Yavuz; Hayiroglu, Mert Ilker; Cagdas, Metin; Rencuzogullari, Ibrahim; ULUGANYAN, MAHMUT; ULUGANYAN, MAHMUTThe PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent Dual Anti-Platelet Therapy (PRECISE-DAPT) score predicts the bleeding risk in patients treated with dual antiplatelet treatment after primary percutaneous coronary intervention (pPCI). This study aimed to determine the predictive value of the admission PRECISE-DAPT score for in-hospital mortality in patients with ST elevation myocardial infarction (STEMI) treated with pPCI. Of the 1418 patients enrolled, the study population was divided into 2 groups: PRECISE-DAPT score >= 25 and PRECISE-DAPT score = 25 compared with the patients whose PRECISE-DAPT score <25 (9.4 vs 0.9%; P < .001, respectively). Both univariate and multivariate Cox proportional hazard analyses showed that the PRECISE-DAPT score is independently associated with in-hospital mortality (hazards ratio [HR]: 1.043, 95% confidence interval [CI]: 1.003-1.084; P = .035; and HR: 1.026, 95% CI: 1.004-1.048; P = .021, respectively). A pairwise comparison of receiver operating characteristic curves showed that the predictive value of the PRECISE-DAPT score with regard to in-hospital mortality was noninferior compared with the Thrombolysis in Myocardial Infarction risk score. The PRECISE-DAPT score may be a significant independent predictor of in-hospital mortality in patients with STEMI treated with pPCI.Publication Open Access Assessment of the Relationship between Monocyte to High-Density Lipoprotein Ratio and Myocardial Bridge.(2019-01-01T00:00:00Z) Bakshaliyev, N; Karacop, E; Cosansu, K; Huyut, MA; Turna, F; Enhos, A; Nadir, A; Ozdemir, R; Uluganyan, MAHMUT; ENHOŞ, ASIM; KARAÇÖP, ERDEM; BAKHSALIYEV, NIJAD; NADİR, AYDIN; ÖZDEMİR, RAMAZAN; ULUGANYAN, MAHMUTBackground: Assessing the monocyte to high-density lipoprotein ratio (MHR) is a new tool for predicting inflamation, which plays a major role in atherosclerosis. Myocardial bridge (MB) is thought to be a benign condition with development of atherosclerosis, particularly at the proximal segment of the brigde. Objective: To evaluate the relationhip between MHR and the presence of MB. Methods: We consecutively scanned patients referred for coronary angiography between January 2013- December 2016, and a total of 160 patients who had a MB and normal coronary artery were enrolled in the study. The patients’ angiographic, demographic and clinic characteristics of the patients were reviewed from medical records. Monocytes and HDL-cholesterols were measured via complete blood count. MHR was calculated as the ratio of the absolute monocyte count to the HDL-cholesterol value. MHR values were divided into three tertiles as follows: lower (8.25 ± 1.61), moderate (13.11 ± 1.46), and higher (21.21 ± 4.30) tertile. A p-value of < 0.05 was considered significant. Results: MHR was significantly higher in the MB group compared to the control group with normal coronary arteries. We found the frequency of MB (p = 0.002) to increase as the MHR tertiles rose. The Monocyte-HDL ratio with a cut-point of 13.35 had 59% sensitivity and 65.0% specificity (ROC area under curve: 0.687, 95% CI: 0.606-0.769, p < 0.001) in accurately predicting a MB diagnosis. In the multivariate analysis, MHR (p = 0.013) was found to be a significant independent predictor of the presence of MB, after adjusting for other risk factors. Conclusion: The present study revealed a significant correlation between MHR and MB.Publication Metadata only Association of neutrophil to lymphocyte ratio with presence of isolated coronary artery ectasia.(2013-03-01T00:00:00Z) Işık, T; Ayhan, E; Uyarel, H; Tanboğa, IH; Kurt, M; Uluganyan, MAHMUT; Ergelen, M; Eksik, A; ULUGANYAN, MAHMUTPublication Metadata only Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Combination Can Predict Prognosis in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention(2015-05-01) Cicek, Gokhan; Acikgoz, Sadik Kadri; Bozbay, Mehmet; Altay, Servet; Ugur, Murat; Uluganyan, MAHMUT; Uyarel, Huseyin; ULUGANYAN, MAHMUTWe assessed the effect of combination of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in predicting in-hospital and long-term mortality in patients (n = 2518) undergoing primary percutaneous coronary intervention (pPCI). Cutoff values for NLR and PLR were calculated with receiver-operating characteristic (ROC) curves. If both PLR and NLR were above the threshold, patients were classified as high risk. If either PLR or NLR was above the threshold individually, patients were classified as intermediate risk. High-risk (n = 693) and intermediate-risk (n = 545) groups had higher in-hospital and long-term mortality (7.2 4% vs 0.7%, P < .001; 14.1, 9.5% vs 4.5%, P < .001, respectively). Classifying patients into intermediate-risk group (hazards ratio [HR]: 1.492, 95% confidence interval [CI]: 1.022-2.178, P = .038) and high-risk group (HR: 1.845, 95% CI: 1.313-2.594, P < .001) was an independent predictor of in-hospital and long-term mortality. The combination of PLR and NLR can be useful for the prediction of in-hospital and long-term mortality in patients undergoing pPCI.Publication Open Access The Impact of Admission Serum Creatinine Derived Estimated Glomerular Filtration Rate on Major Adverse Cardiac Events in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention(2016-04-01) ULUGANYAN, MAHMUT; KARACA, GÜRKAN; ULUTAŞ, TÜRKER KEMAL; EKMEKÇİ, AHMET; BAKSHALİYEV, NİJAD; MURAT, AHMET; KÖROĞLU, BAYRAM; UYAREL, HÜSEYİN; EREN, MEHMET; ULUGANYAN, MAHMUT; BAKHSALIYEV, NIJADBackground: The impact of Cockroft-Gault (C-G) derived estimated glomerular filtration rate (eGFR) on mortality and major adverse cardiac events (MACEs) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI) was assessed. Methods: A total of 884 patients were classified into four categories according to admission creatine derived eGFR: < 60, 60 - < 90, 90 - < 120, and ≥ 120 mL/min/1.73 m(2). Results: In-hospital and long-term MACEs were significantly higher in eGFR < 60 mL/min/1.73 m(2) subgroup (P < 0.001 and P = 0.028). Multivariate analysis demonstrated 7.78-fold (95% CI: 0.91 - 66.8) higher mortality risk in eGFR < 60 mL/min/1.73 m(2) subgroup. Conclusion: As an easily applicable bedside method, C-G derived eGFR could be important for prediction of in-hospital and long-term mortality and MACE in STEMI patients undergoing primary PCI.Publication Metadata only Usefulness of the thrombolysis in myocardial infarction risk index in acute heart failure: a pilot study(2016-12-01) Ekmekci, Ahmet; Keskin, Muhammed; Guvenc, Tolga Sinan; Uluganyan, MAHMUT; Karaca, Gurkan; Hayiroglu, Mert Ilker; Agustos, Semra Simsek; Eren, Mehmet; ULUGANYAN, MAHMUTBackground: Risk stratification in acute heart failure (AHF) is vital for both physicians and paramedical personals. Thrombolysis in myocardial infarction (TIMI) risk index (TRI) and modified TRI (mTRI) are novel and simple predictive risk indices that have been examined in patients with acute coronary syndrome.Publication Open Access The prognostic value of fragmented QRS in patients undergoing transcatheter aortic valve implantation(2018-11-01) Ay, Nuray Kahraman; ENHOŞ, ASİM; AY, YASİN; Ozdemir, Razaman; NADİR, AYDIN; KARAÇÖP, ERDEM; ÇELİKKALE, İLKE; ULUGANYAN, MAHMUT; Goktekin, Omer; KAHRAMAN AY, NURAY; ENHOŞ, ASIM; AY, YASİN; BAKHSALIYEV, NIJAD; NADİR, AYDIN; KARAÇÖP, ERDEM; ÇELİKKALE, İLKE; ULUGANYAN, MAHMUT; ÖZDEMİR, RAMAZANBackground Although transcatheter aortic valve implantation (TAVI) can successfully correct aortic narrowing, pre-existing pathophysiological alterations in the left ventricle are still a concern in terms of long-term mortality. This study aimed to examine the predictive role of fQRS morphology on long-term prognosis in patients undergoing TAVI due to severe aortic stenosis. Methods A total of 117 patients undergoing TAVI due to severe aortic stenosis were included in this retrospective cohort study. Patients were assigned into two groups based on the presence (n = 36) or absence (n = 81) of fQRS. Predictors of long-term survival were estimated. Results In-hospital mortality was higher in fQRS group (5.5% vs. 1.2%, p = 0.0224). In the long-term, fQRS (OR: 3.06, 95% CI 1.29–7.27, p: 0.01), LVEF <50% (OR: 2.54, 95% CI 1.07–6.02, p: 0.03) and presence of atrial fibrillation (OR: 2.42, 95% CI 1.05–5.60, p: 0.03) emerged as significant independent predictors of short survival. Conclusion Presence of fQRS on ECG, an indirect indicator of myocardial fibrosis, seems to have the potential to be used as a prognostic marker after TAVI procedure. Large prospective studies are warranted.Publication Metadata only Relationship between R-wave peak time and no-reflow in ST elevation myocardial infarction treated with a primary percutaneous coronary intervention(2017-06-01) Cagdas, Metin; Karakoyun, Suleyman; Rencuzogullari, Ibrahim; Karabag, Yavuz; Yesin, Mahmut; Uluganyan, MAHMUT; Gursoy, Mustafa O.; Artac, Inanc; Ilis, Dogan; Efe, Suleyman C.; Tasar, Onur; ULUGANYAN, MAHMUTObjectives Coronary no-reflow (NR) is observed in nearly half of ST segment elevation myocardial infarction (STEMI) patients who undergo a primary percutaneous coronary intervention (pPCI) despite epicardial coronary vessel patency. Several methods used to define NR include thrombolysis in myocardial infarction grade, corrected thrombolysis in myocardial infarction frame count, myocardial blush grade, ST-segment resolution, contrast echocardiography, and MRI. The aim of our study was to evaluate the relationship between NR and R-wave peak time (RWPT) measured from infarct-related artery leads