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ULUGANYAN, MAHMUT

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ULUGANYAN
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    Korona Virüs Hastalığı 2019 ve Kalp
    (2020-10-01T00:00:00Z) Uluganyan, Mahmut; ULUGANYAN, MAHMUT
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    Impact of atrial flow regulator (AFR) implantation on 12-month mortality in heart failure Insights from a single site in the PRELIEVE study
    (2021-08-01T00:00:00Z) BAKHSALIYEV, NIJAD; ÇELİKKALE, İLKE; ENHOŞ, Asim; KARAÇÖP, ERDEM; ULUGANYAN, Mahmut; ÖZDEMİR, Ramazan; BAKHSALIYEV, NIJAD; ÇELİKKALE, İLKE; ENHOŞ, ASIM; KARAÇÖP, ERDEM; ULUGANYAN, MAHMUT; ÖZDEMİR, RAMAZAN
    Background Implantation of the atrial flow regulator (AFR) to create an interatrial left-to-right shunt has been shown to be safe and feasible to reduce intracardiac filling pressures in patients with heart failure (HF). Objectives We aimed to assess the effect of AFR implantation on 12-month mortality and hospitalization rates in patients with reduced (HFrEF) or preserved HF (HFpEF). Methods One-year follow-up data from 34 subjects enrolled at a single PRELIEVE center were analyzed. The 12-month predicted mortality was calculated using the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) risk score. Patients were divided into two groups, according to their history of hospitalizations for HF. Results Study data of 34 patients (HFrEF: 24 [70.6%]; HFpEF: 10 [29.4%]) were assessed. Median follow-up duration was 355 days. In total, 14 (41.2%) patients were hospitalized during the follow-up period and 6 (17.6%) of these patients were hospitalization for HF (HHF). A total of 24 hospitalizations occurred in this period and 8 (33%) hospitalizations were for HHF. The median baseline MAGGIC score was 23 and the median predicted mortality was 13.4/100 patient years. Observed mortality was 3.1/100 patient years. The observed survival (97%) was 10.3% (95% confidence interval 3.6-17.5%, p = 0.004) better than the predicted survival (86.6%). Conclusion Our results suggest that AFR implantation has favorable effects on mortality in patients with heart failure, regardless of ejection fraction. Furthermore, compared to baseline, left ventricular filling pressure (assessed by echocardiography) decreased significantly without right side volume overload at the 1-year follow-up.
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    covid-19 pandemisinde hastalık/hastane yönetimi
    (2021-11-01T00:00:00Z) Uluganyan, Mahmut; Özdemir, Ramazan; ULUGANYAN, MAHMUT; ÖZDEMİR, RAMAZAN
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    The effect of 5-day course of hydroxychloroquine and azithromycin combination on QT interval in non-ICU COVID19(+) patients
    (2020-09-01T00:00:00Z) Bakhshaliyev, Nijad; ULUGANYAN, Mahmut; ENHOŞ, Asim; KARAÇÖP, ERDEM; ÖZDEMİR, Ramazan; BAKHSALIYEV, NIJAD; ULUGANYAN, MAHMUT; ENHOŞ, ASIM; KARAÇÖP, ERDEM; ÖZDEMİR, RAMAZAN
    Background: The combination of Hydroxychloroquine (HCQ) and azithromycin showed effectiveness as a treat-ment for COVID-19 and is being used widely all around the world. Despite that those drugs are known to cause prolonged QT interval individually there is no study assessing the impact of this combination on electrocardiography (ECG). This study aimed to assess the impact of a 5-day course of HCQ and azithromycin combination on ECG in non-ICU COVID19(+) patients.
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    A Brief Reconnoitre about Effects of MMP9 on Aortic Dissection
    (2021-11-01T00:00:00Z) Uluganyan, Mahmut; ULUGANYAN, MAHMUT
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    PublicationOpen Access
    The Treatment Role of Anti-aggregants and Anti-coagulants in Radial Artery Occlusion after Transradial Coronary Angiography
    (2023-07-01) Nadir A.; Uluganyan M.; NADİR, AYDIN; ULUGANYAN, MAHMUT
    Objective: The transradial approach (TRA) has been widely used for coronary procedures. The rate of complications such as bleeding, hematoma and pseudoaneurysm is reduced with TRA. The purpose of this study is to search the treatment role of anti-aggregants and low molecular weight heparins (LMWH) in situation of radial artery occlusion (RAO). Methods: A total of 239 patients (140 men, 58.6%) were included. Of the patients 159 (66.5%) were elective, and 80 (33.5%) had acute coronary syndrome. When RAO was detected, patients were treated with 2 weeks of LMWH. Results: In 23 (9.6%) of 239 patients, RAO was observed. From the 23 patients with RAO, 12 (52.8%) were using anti-aggregants, and the remaining 11 (47.8%) did not use. In terms of RAO, a statistically significant difference was observed between antiaggregant users and non-users (p<0.001). In the group using antiaggregants and LMWH a statistically significant improvement was observed in the radial flow compared with the group treated withLMWH alone (p<0.001). Conclusion: In the present study, we showed that the addition of anti-aggregants to anti-coagulants decreased RAO rate, declined the symptoms of RAO, also potentiated the effects of anti-coagulants and resulted in better recanalization rate of RAO