Person: TAŞLIDERE, ELİF
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Publication Metadata only Ascorbic acid and beta-carotene reduce stress-induced oxidative organ damage in rats.(2016-10-01) Esrefoglu, MUKADDES; AKINCI, A; TASLIDERE, ELİF; ELBE, H; CETIN, A; ATES, B; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİFPublication Metadata only The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats.(2016-04-01) TASLIDERE, ELİF; VARDI, N; Esrefoglu, MUKADDES; ATES, B; TASKAPAN, C; YOLOGLU, S; TAŞLIDERE, ELİF; EŞREFOĞLU, MUKADDESPublication Metadata only The protective effect of melatonin in lungs of newborn rats exposed to maternal nicotine.(2018-01-01) YILDIZ, A; VARDI, N; KARAASLAN, MG; ATES, B; TASLIDERE, ELİF; Esrefoglu, MUKADDES; TAŞLIDERE, ELİF; EŞREFOĞLU, MUKADDESPublication Metadata only Melatonin, quercetin and resveratrol attenuates oxidative hepatocellular injury in streptozotocin-induced diabetic rats.(2015-09-01) ELBE, H; Esrefoglu, MUKADDES; VARDI, N; TASLIDERE, ELİF; OZEROL, E; TANBEK, K; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİFPublication Open Access Development of the Esophagus and Stomach(2017-10-01) Esrefoglu, MUKADDES; Taslidere, ELİF; Cetin, Asli; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİFEpithelial components of the organs of the digestive system are derived from the endoderm, whereas connective tissue and muscle components are derived from the mesoderm. At the 3rd-4th week of development, as a result of cephalocaudal and lateral foldings of the embryo, a portion of the endoderm-lined yolk sac cavity is incorporated in the embryo to form the primitive gut. Primitive gut is composed of four main regions: pharyngeal gut, foregut, midgut, and hindgut. The esophagus and stomach are derived from the foregut. The development of the esophagus is characterized by lengthening, widening, thickening, and histological changes. The development of the stomach is characterized by widening, thickening, and histological changes as well as positional changes. In the present study, we tried to review the morphological and functional development of the esophagus and stomach with the aid of pictures obtained from various stages of prenatal and postnatal development of the organs of rats. Previous reviews lack information on both histological and functional development of the organs.Publication Open Access Melatonin is effective in reducing stress-induced organ damage in Wistar albino rats(2014-01-01T00:00:00Z) Esrefoglu, MUKADDES; AKINCI, Aysin; Elbe, Hulya; TAŞLIDERE, ELİF; Cetin, Asli; ATEŞ, BURHAN; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİFIn the present study, we tried to investigate the effects of melatonin, a novel antioxidant and a potent free radical scavenger, in stress-induced cerebral, cerebellar, cardiac, and hepatic oxidative damage using microscopic and biochemical analysis. A total of 32 male Wistar albino rats were divided into control, stress, stress + saline, and stress + melatonin groups. The rats from the stress groups were exposed to high stress conditions of starvation, immobilization, and cold exposure. The rats from the stress + melatonin group received melatonin daily at 20 mg/kg body weight intraperitoneally for 7 days. At the end of the experiment, the brain, cerebellum, heart, and liver were rapidly removed. The main histopathological damage scores (MHDSs) of the stress and stress + saline groups were higher than those of control group for all of the organs. The MHDSs of melatonin-administered group were lower than those of stress and stress + saline groups. The main tissue superoxide dismutase activities of the stress + melatonin group were even higher than those of the control group in the cerebellum and liver, and main tissue catalase activities of the stress + melatonin group were even higher than those of control group in all of the organs. As a conclusion, we found melatonin very effective in reducing stress-induced organ damage by inhibiting lipid peroxidation and supporting the cellular antioxidant defense system.Publication Metadata only Protective effects of melatonin and quercetin on experimental lung injury induced by carbon tetrachloride in rats.(2014-03-01) TASLIDERE, ELİF; Esrefoglu, MUKADDES; ELBE, H; CETIN, A; ATES, B; TAŞLIDERE, ELİF; EŞREFOĞLU, MUKADDES