Person: TAŞLIDERE, ELİF
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Publication Metadata only Protective effect of melatonin and quercetin in carbon tetrachloride induced lung injury(2014-01-21) TAŞLIDERE, ELİF; ELBE, HÜLYA; ÇETİN, ASLI; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİF; EŞREFOĞLU, MUKADDESPublication Metadata only Effects of ciprofloxacin on fetal rat liver during pregnancy and protective effects of quercetin.(2017-01-01) DOGAN, Z; ELBE, H; Taslidere, ELİF; SOYSAL, H; CETIN, A; DEMIRTAS, S; TAŞLIDERE, ELİFPublication Metadata only Design of Xylose-Based Semisynthetic Polyurethane Tissue Adhesives with Enhanced Bioactivity Properties.(2016-02-01T00:00:00Z) BALCIOGLU, S; PARLAKPINAR, H; VARDı, N; DENKBAS, EB; KARAASLAN, MG; GULGEN, S; Taslidere, ELİF; KOYTEPE, S; ATEŞ, B; TAŞLIDERE, ELİFPublication Metadata only Therapeutic effects of melatonin and quercetin on carbon tetrachloride-induced cardiac damage in rats(2016-03-01) ELBE, HÜLYA; EŞREFOĞLU, MUKADDES; CETIN, A; TAŞLIDERE, ELİF; ATES, BURHAN; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİFPublication Metadata only Ascorbic acid and beta-carotene reduce stress-induced oxidative organ damage in rats.(2016-10-01) Esrefoglu, MUKADDES; AKINCI, A; TASLIDERE, ELİF; ELBE, H; CETIN, A; ATES, B; EŞREFOĞLU, MUKADDES; TAŞLIDERE, ELİFPublication Metadata only Effects of melatonin on acetylsalicylic acid induced gastroduodenal and jejunal mucosal injury(2018-01-01T00:00:00Z) taslidere, elif; VARDI, NİGAR; PARLAKPINAR, HAKAN; YILDIZ, AHMET; Taslidere, BAHADIR; Karaaslan, M. G.; TAŞLIDERE, ELİF; TAŞLIDERE, BAHADIRWe evaluated the effects of melatonin on acetylsalicylic acid (ASA) induced gastroduodenal and jejunal mucosal injury. We used 40 postpubertal rats divided randomly into five groups of eight animals. The control group consisted of untreated animals. The Mel group was injected intraperitoneally (i.p.) with 5mg/kg melatonin. The ASA group was injected i.p. with 200mg/kg ASA. The ASA + Mel group was injected i.p. with 5mg/kg melatonin 45min after administering 200mg/kg ASA i.p. The Mel + ASA group was injected i.p. with 5mg/kg melatonin 45min before administering 200mg/kg ASA i.p. We found no statistically significant differences in mean histopathological scores in the ASA + Mel group compared to the ASA group. ASA caused shortened villi and loss of the apical villus in the duodenum. The histopathological score was increased and villus height was decreased in the ASA group compared to untreated controls. Treatment with melatonin attenuated the histological damage. In the ASA group, occasional areas showed erosion of villi in the jejunum; however, differences in mean histopathological score in ASA group compared to the other groups were not statistically significant. Malondialdehyde (MDA), glutathione (GSH) and superoxide dismutase (SOD) activities were measured in stomach, duodenal and jejunum tissue. We found increased MDA activity in both stomach and duodenal tissues in the ASA group compared to the control group (p<0.05). We found no statistically significant changes in MDA levels in jejunal tissue in the ASA group compared to the control group. We found no change in SOD activity in either stomach or duodenal tissues in the ASA group compared to the control group. We observed decreased SOD activity in jejunal tissue in the ASA group compared to the control group (p<0.05). We detected no change in GSH activity in stomach, duodenal or jejunal tissues in the ASA group compared to the control group. The stomach damage was less in melatonin treated groups, but the lesions were not completely eliminated. The jejunum in the ASA group retained a nearly normal appearance. We found that melatonin exhibited some healing effects on ASA induced duodenal mucosal injury.Publication Metadata only The Effect of Ceftriaxone on Testicular Connexin 43 Expression.(2016-03-01T00:00:00Z) Sahin, Levent; Sahin, Hilal; VARDI, NİGAR; Karahan, Feride; YILDIZ, AZİBE; TAŞLIDERE, ELİF; GÜL, SEMİR; TAŞLIDERE, ELİFPublication Metadata only Beta-glucan attenuates cerebral ischemia/reperfusion-induced neuronal injury in a C57BL/J6 mouse model(2019-01-01T00:00:00Z) KAYA, KÜRŞAT; ÇİFTÇİ, OSMAN; ÖZTANIR, MUSTAFA NAMIK; TAŞLIDERE, ELİF; BAŞAK TÜRKMEN, NEŞE; TAŞLIDERE, ELİFBeta-glucans (beta g), that have many useful effects on human health, are natural polysaccharides. Our aim in this study was to determine useful effect of beta g against oxidative and neuronal damage caused by global cerebral ischemia/reperfusion (IR) in stroke imitated mice via surgical operation. A total of 40 mice divided into four equal groups randomly. The group 1 (sham operated) was kept as control. Bilateral carotid arteries of subjects in group 2 (I/R) and group 4 (I/R + beta g) were clipped for 15 min, and the mice in group 4 (I/R + beta g) were treated with beta g (50 mg/kg/day), while the mice in group 2 (I/R) were treated with only vehicle for 10 days. The mice of group 3 (beta g) were treated with beta g for 10 days without carotid occlusion. Global cerebral I/R significantly increased oxidative stress and decreased members of anti-oxidant defense system. In addition, I/R caused histopathological damage in the brain tissue. However, beta g treatment ameliorated both oxidative and histopathological effects of I/R. Our present study showed that beta g treatment significantly ameliorated oxidative and histological damage in the brain tissue caused by cerebral I/R. Therefore, beta g treatment can be used as supportive care for ischemic stroke patients.Publication Metadata only The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats.(2016-04-01) TASLIDERE, ELİF; VARDI, N; Esrefoglu, MUKADDES; ATES, B; TASKAPAN, C; YOLOGLU, S; TAŞLIDERE, ELİF; EŞREFOĞLU, MUKADDESPublication Metadata only The protective effect of melatonin in lungs of newborn rats exposed to maternal nicotine.(2018-01-01) YILDIZ, A; VARDI, N; KARAASLAN, MG; ATES, B; TASLIDERE, ELİF; Esrefoglu, MUKADDES; TAŞLIDERE, ELİF; EŞREFOĞLU, MUKADDES