Person: DOĞAN, GÜZİDE
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Publication Metadata only Teething and affecting factors: experiences from Turkey.(2016-12-01T00:00:00Z) Yilmaz, Ayse E; Dogan, Güzide; Akelma, Ahmet Z; Karabel, Musemma; Karabel, Duran; Akca, Halise; Erdur, Emire A; DOĞAN, GÜZİDEPublication Metadata only The effect of Celiac disease on cardiac functions and aortic elasticity parameters in children.(2020-12-10T00:00:00Z) Alkan, Fatos; Dogan, Güzide; Kasırga, Erhun; Coskun, Senol; DOĞAN, GÜZİDEPublication Metadata only Clinical significance of low transaminase levels in children with inflammatory bowel disease(2019-04-01T00:00:00Z) ÇAKIR, MURAT; Sag, Elif; Dogan, Güzide; Unal, Fatih; Kasirga, Erhun; DOĞAN, GÜZİDEBackgroundLow alanine aminotransaminase (LALT) levels may be seen in patients with inflammatory bowel disease (IBD), but there has been no study about the frequency and its clinical significance. We aimed to analyze the frequency of LALT, and its clinical significance in children with IBD.MethodsThe study included the 89 patients with IBD without hepatobiliary involvement. LALT was defined as ALT levels <5 U/L. Demographic and clinical findings and outcome of the patients with and without LALT were compared.ResultsLALT was found 47.1% of the patients. At initial examination, it was more common in female patients (92.3 vs. 41.3%, P<0.001) and patients with CD (57.7 vs. 30.2%, P=0.01). 75% of the patients with penetrating Crohn-s disease (CD) had LALT (P=0.002). Hemoglobin (10.42.1 vs. 11.7 +/- 1.9g/dL, P=0.01), folic acid (5.2 +/- 3.3 vs. 8.6 +/- 5.9ng/mL, P=0.02) and serum albumin levels (3.6 +/- 0.8 vs. 4.7 +/- 5g/dL, P=0.002) were significantly low in patients with LALT. LALT was associted with the disease relapse within 2weeks in 12 of the 16 patients with LALT whereas it was seen in 16 of the 73 patients without LALT during the follow-up (75 vs. 21.9%, P<0.001). Additionally, steroid dependency was more common in patients with LALT during the follow-up (62.5 vs. 12.3%, P<0.001).ConclusionsLALT is common in children with IBD especially in CD and associated with low hemoglobin, albumin and folic acid levels. It may be a marker of relapse and steroid dependency.Publication Metadata only Should we worry about the eyes of celiac patients?(2020-09-01T00:00:00Z) Dogan, Güzide; Sen, Semra; Cavdar, Ercument; Mayali, Huseyin; Ozyurt, Beyhan Cengiz; Kurt, Emin; Kasirga, Erhun; DOĞAN, GÜZİDEPurpose: In this article, we evaluate subfoveal choroidal thickness in celiac patients with respect to adherence to the gluten-free diet and nonadherence to the gluten-free diet, comparing with age and sex matched healthy controls using spectral-domain optical coherence tomography. Materials and Methods: A case-control study among 42 celiac patients and 42 healthy participants was conducted in the Department of Pediatric Gastroenterology. Celiac patients of our policlinics compliant with spectral-domain optical coherence tomography examination enrolled in the study. Celiac patients had been asked verbally about their adherence to gluten-free diet, were evaluated according to negative or positive EmA and anti-TG2 for defining adherence, and were divided into two groups (adherence to gluten-free diet and nonadherence to gluten-free diet). Results: Subfoveal choroidal thickness was thinner in EmA (+) or anti-TG2 (+) eyes than EmA(-) or anti-TG2 (-) eyes in celiac patients, but it was not statistically significant. The mean subfoveal choroidal thickness values in eyes with celiac disease, whose diagnosis time was longer than 60 months, were thinner than shorter group. Longer duration of gluten-free diet was associated with adherence difficulty and thinner choroidal thickness (r = -0.15, p = 0.34). Adherence to gluten-free diet was 88.2% for children below the age of 60 months and 57.1% for children older than 60 months. Conclusion: In conclusion, in addition to other extraintestinal manifestations of celiac disease, diagnosis time longer than 60 months in pediatric celiac patients, nonadherence to the gluten-free diet, and antibody positivity should be focused on during ophthalmologic examination and choroid measurement.Publication Metadata only Neonatal Cholestasis as Initial Presentation of Portosystemic Shunt: A Case Report(2016-12-01T00:00:00Z) Dogan, Güzide; Duzgun, Fatih; Tarhan, Serdar; Appak, Yeliz Cagan; Kasrga, Erhun; DOĞAN, GÜZİDECongenital intrahepatic portosystemic shunts are rare in children. Portosystemic venous malformations are characterized by extreme clinical variability. We report a full-term 33-day-old male infant presenting with neonatal jaundice. On physical examination, he had generalized icterus and the liver was palpable 3.5 cm below the right costal margin. He had no other symptoms. Laboratory tests showed AST 632 U/L, ALT 198 U/L, total bilirubin 12.1 mg/dL, conjugated bilirubin 10.2 mg/dL, alkaline phosphatase 753 U/L, GGT 47 U/L and glucose 67 U/L. Colour Doppler ultrasonography showed the left portal vein was more dilated than the right portal branch and communication with dilated left hepatic vein. There was no evidence of portal hypertension, heart failure, hepatopulmonary syndrome and encephalopathy during his hospital stay, so he was discharged from the pediatric department and his parents advised to attend monthly follow-up. Congenital portosystemic shunts are rarely observed in the childhood period. 1 Depending on anatomic characteristics they may be intrahepatic or extrahepatic. 2 Intrahepatic portosystemic shunts (PSS) are observed between the portal vein and hepatic vein or vena cava inferior. 3,4 Small shunts may close themselves before the age of 2 years. 5 With the increase in use of imaging methods, diagnosing PSS has become easier, with an increase in the number of cases reported. 6 Neonatal cholestatis is a frequent complication of PSS. 1 We present a case presenting with neonatal cholestasis diagnosed with congenital intrahepatic PSS.Publication Metadata only A child with bilateral multiple renal cysts presenting with ascites and pleural effusion: Questions and Answers(2019-09-01T00:00:00Z) Agbas, Ayse; Aksu, Bagdagul; Dogan, Güzide; Ikizceli, Turkan; Selcuk, Hatice Nilgun Duru; Elevli, Murat; DOĞAN, GÜZİDEPublication Metadata only Supernumerary nipple: Should we be alert?(2010-08-01T00:00:00Z) Yilmaz, Ayse Esra; Sarifakioglu, Evren; Dogan, Güzide; Cakir, Banu; Karabel, Musemma; Gorpelioglu, Canan; Turkay, Sadi; DOĞAN, GÜZİDEPublication Metadata only Vitamin D Deficiency in Children and Adolescents(2012-01-01T00:00:00Z) Andiran, Nesibe; Celik, Nurullah; Akca, Halise; Dogan, Güzide; DOĞAN, GÜZİDEObjective: Vitamin D deficiency is an important health problem in both developed and developing countries. Recent reports on the extraskeletal effects of vitamin D have led to increased interest in prevalence studies on states of deficiency/insufficiency of vitamin D. The aim of this study was to determine the frequency of vitamin D deficiency and insufficiency in children and adolescents residing in Ankara, Turkey and to investigate the factors associated with low vitamin D status.Publication Metadata only Clinical findings, child and mother psychosocial status in functional constipation(2017-11-01T00:00:00Z) Appak, Yeliz Cagan; Sapmaz, Sermin Yalin; Dogan, Güzide; Herdem, Ahmet; Ozyurt, Beyhan Cengiz; Kasirga, Erhun; DOĞAN, GÜZİDEBackground/Aims: Functional constipation (FC) is a common problem in childhood. In this study, we aimed to analyze the clinical and sociodemographic findings of patients with FC, parenting behaviors, and psychosocial states of children and parents.Publication Metadata only Is low FODMAP diet effective in children with irritable bowel syndrome?(2020-01-01T00:00:00Z) Dogan, Güzide; Yavuz, Sibel; Aslantas, Hale; Ozyurt, Beyhan Cengiz; Kasirga, Erhun; DOĞAN, GÜZİDEOBJECTIVE: There is growing evidence that suggests that consumption of fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) may result in some symptoms in certain patients with irritable bowel syndrome (IBS). This study aims to evaluate the efficacy of a low FODMAP diet in children with IBS by comparing it with the standard diet.