Person: ZENGİN ÇELİK, TUĞBA
Status
Search Results
Treatment of Root Surface Covering By Acellular Dermal Matrix
With increase in esthetic expectations, the treatment of gingival recessions has gained importance in last few years. The aim of this treatment is to cover root surface and gain satisfactory esthetical results. Today there are many surgical methods available for this purpose. The use of sub-epithelial connective tissue graft with coronal position flap is the gold standard in the treatment of gingival recessions. However, there are some drawbacks, such as limited donor area of sub-epithelial connective tissue graft and existence of the second operational area. In order to overcome these disadvantages, acellular dermal matrixes are used in periodontal plastic surgeries as alternatives to autogenous grafts. In single tooth Miller Class I and Class II gum recessions, the best predictable results can be obtained by sub-epithelial connective tissue grafts. In addition to this, the use of acellular dermal matrix along with coronal position flap can be evaluated as an alternative for autogenous donor area.
Original Research Clinical and Microbiological Effects of the Use of Erbium: Yttrium–Aluminum–Garnet Laser on Chronic Periodontitis in Addition to Nonsurgical Periodontal Treatment: A Randomized Clinical Trial—6 Months Follow-Up
Evaluation of the effect of topical and systemic ozone application in periodontitis: an experimental study in rats
Objective: The goal of the present study was to determine the effect of systemic and topical ozone application on alveolar bone loss (ABL) by evaluating the effect of Hypoxia-inducible factor -1 alpha (HIF-1-alpha) and receptor activator of NF-kappa B ligand (RANKL)-positive cells on histopathological and immunohistochemical changes in a rat periodontitis model. Methodology: Thirty male Wistar rats were divided into three groups: 1) Group C (control group); 2) Group SO (systemic ozone group) and 3) Group TO (topical ozone group). Experimental periodontitis was induced with a 3/0 silk suture placed at the mandibular left first molars of rats, and the suture was removed 14 days later. Ozone gas was injected intraperitoneally (0.7 mg/kg) in SO group. Topical ozone application protocol was performed using an ozone generator at 80% concentration (4th grade) 90- degree probe for the duration of 30 s. Both ozone applications were carried out for two weeks at intervals of two days. Histomorphometric and immunohistochemical analysis were performed. Results: ABL was significantly lower in Group SO compared to Group C (p: 0.0052). HIF-1 alpha- positive cells were significantly lower in Group TO than in Group C (p: 0.0043). RANKL-positive cells were significantly lower in Group SO and in Group TO compared to the control group (p: 0.0033, p: 0.0075, respectively). Conclusion: Both ozone applications decreased RANKL-positive cell counts, TO application decreased HIF-1-alpha positive cells counts, and SO application was found to be more effective in reducing ABL compared to control group.