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Now showing 1 - 10 of 155
  • Publication
    Complete seizure freedom is possible in patients with MTLE-HS after surgery in spite of extratemporal electro-clinical features
    (2015-07-01) TOYDEMIR, Hulya Ertasoglu; Ozkara, Cigdem; Uysal, Omer; Ozyurt, Emin; Uzan, Mustafa; UYSAL, ÖMER
    Purpose: The aim was to identify the common typical and atypical ictal semiologic and EEG features of patients with mesial temporal lobe epilepsy and hippocampal sclerosis who became seizure-free postoperatively.
  • Publication
    Cross - cultural adaptation and preliminary validation of the Turkish version of the Early Childhood Oral Health Impact Scale among 5-6-year-old children
    (2011-12-22) Peker, Kadriye; Uysal, Omer; Bermek, Gulcin; UYSAL, ÖMER
    Background: In Turkey, formal pre-primary education for children 5-6 years old provides the ideal setting for school-based oral health promotion programs and oral health care services. To develop effective oral health promotion programs, there is a need to assess this target group-s subjective oral health needs as well as clinical needs. The Early Childhood Oral Health Impact Scale (ECOHIS) is a well-known instrument for assessing oral health quality of life in children aged 0-5 years old and their families. This study aimed to adapt the ECOHIS for children 5-6 years old in a Turkish-speaking community and to undertake a preliminary investigation of its psychometric properties.
  • Publication
    The effect of the SIRT1 2827 A > G polymorphism, resveratrol, exercise, age and occupation in Turkish population with cardiovascular disease
    (2015-02-01) IZMIRLI, Muzeyyen; GOKTEKIN, Omer; Bacaksiz, AHMET; Uysal, Omer; Kilic, Ulkan; BACAKSIZ, AHMET; UYSAL, ÖMER
    Objective: Cardiovascular disease (CVD) is the leading cause of death in Europe. One of the candidate molecule affecting epigenetic mechanisms of CVD is the SIRT1, a subclass of sirtuins, is located on the long arm of chromosome 10 (10q21.3). Particularly, the relation between 2827 A>G polymorphism of the SIRT1 positioned on exon 2, leading to conversion of histidine to arginine, and the formation of CVD is not known yet. One of the activator of SIRT1, resveratrol, is also known as a cardioprotective molecule. On the other hand, the parameters including exercise, occupation and age affect CVD. The aim of the present study was to investigate the effect of the rs144124002 (2827 A>G) single nucleotide polymorphisms (SNP) of SIRT1 and exercise-occupation-age parameters on CVD. Methods: SNP of SIRT1 were analyzed using DNA isolation, the polymerase chain reaction (PCR) and restriction fragment length polymorphism. To do so, large cohorts of CVD patients (n=293) and healthy controls (n=117) who directed Cardiology Department of Bezmialem Vakıf University, Bezmialem Vakıf University Hospital were used. Results: In this study, when we assessed CVD and control groups about 2827 A>G polymorphism, all individuals were determined as homozygous genotype. We found a positive effect between the modifications of resveratrol, exercise, age and occupation and CVD (OR=0.17; CI 95%, 0.1-0.2; p≤0.001). Conclusion: This is the first study demonstrating the correlation between the SIRT1 rs144124002 polymorphism and CVD in Turkish population. (Anatolian J Cardiol 2015; 15: 103-6) Key words: SIRT1, resveratrol, epigenetic, polymorphism, cardiovascular disease
  • Publication
    A randomized controlled trial of home monitoring versus hospitalization for mild non-alcoholic acute interstitial pancreatitis: A pilot study
    (2014-05-01) Ince, ALİ TÜZÜN; Senturk, HAKAN; Singh, Vikesh K.; YILDIZ, Kemal; DANALIOGLU, Ahmet; CINAR, Ahmet; Uysal, Omer; KOCAMAN, Orhan; BAYSAL, Birol; Guerakar, Ahmet; İNCE, ALİ TÜZÜN; ŞENTÜRK, HAKAN; UYSAL, ÖMER
    Background/Objectives: Acute pancreatitis (AP) is a disease typically requiring in-hospital treatment. We conducted a trial to assess the feasibility of early discharge from the hospital for patients with mild nonalcoholic acute pancreatitis (NAAP).
  • Publication
    Influence of Adhesive Application Methods and Rebonding Agent Application on Sealing Effectiveness of All-in-One Self-Etching Adhesives
    (2013-10-01) Demirci, Mustafa; Tuncer, Safa; Tekce, Neslihan; Erdilek, Dina; Uysal, Omer; UYSAL, ÖMER
    Statement of Problem The choice of adhesive application methods could affect the microleakage of self-etch adhesives.
  • Publication
    Hydrosonographic assessment of the effects of 2 different suturing techniques on healing of the uterine scar after cesarean delivery
    (2014-06-01) Sevket, OSMAN; Ates, SEDA; MOLLA, Taner; OZKAL, Fulya; Uysal, Omer; Dansuk, RAMAZAN; ŞEVKET, OSMAN; ATEŞ, SEDA; UYSAL, ÖMER; DANSUK, RAMAZAN
    Objective: To compare the effects of 2 suturing techniques (single versus double layer) on healing of the uterine scar after a cesarean delivery. Methods: In the present randomized, prospective study, 36 women with a term pregnancy who had an elective cesarean delivery were randomly assigned to closure of the uterine incision with a single-layer locked suture or with a double-layer locked/unlocked suture. Six months after the operation, the integrity of the cesarean scar at the uterine incision site was assessed by hydrosonography. The healing ratio and the thickness of the residual myometrium covering the defect were calculated as markers of uterine scar healing. Results: There were no significant differences between the groups in terms of estimated blood loss, operation time, or additional hemostatic suture. However, the mean thickness of the residual myometrium covering the defect was 9.95 +/- 1.94 mm after a double-layer closure and 7.53 +/- 2.54 mm after a single-layer closure (P = 0.005). The mean healing ratio was significantly higher after a double-layer closure (0.83 +/- 0.10) than after a single-layer closure (0.67 +/- 0.15; P = 0.004). Conclusion: A double-layer locked/unlocked closure of the uterine incision at cesarean delivery decreases the risk of poor uterine scar healing. (C) 2014 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
  • Publication
    Dental Training and Changes in Oral Health Attitudes and Behaviors in Istanbul Dental Students
    (2010-09-01) Peker, Kadriye; Uysal, Oemer; Bermek, Guelcin; UYSAL, ÖMER
    The aim of this study was to examine the changes that occur in the oral health attitudes and behaviors of dental students in Istanbul, Turkey, during their dental education. The Turkish version of the Hiroshima University-Dental Behavioral Inventory (HU-DBI) was distributed among 757 dental students at the Dental Faculty, Istanbul University. The response rate was 72 percent. Chi-square and logistic regression models were used for statistical analysis. The mean HU-DBI score of the clinical students was significantly higher than that of the preclinical students. Preclinical students significantly more often believed that it was impossible to prevent gum disease with toothbrushing alone and worried about the color of their teeth and had breath. Most of them brushed their teeth with strong strokes, thought the condition of their teeth was getting worse despite daily toothbrushing, and would seek dental care only when symptoms arise. Clinical students more often used disclosing solutions to see how clean their teeth were and complained of bleeding gums. The variation in favorable oral health attitudes/behaviors appeared to reflect the students- educational training experience. The findings of this study highlight the relatively poor oral health behaviors of Turkish dental students, which should be improved by means of comprehensive programs that aim to promote their own dental hygiene practices and preventive oral health knowledge from the start of dental training.
  • Publication
    SIRT1 gene variants are related to risk of childhood obesity
    (2015-04-01) Kilic, Ulkan; GOK, Ozlem; ELIBOL-CAN, BİRSEN; Ozgen, Ilker Tolga; Erenberk, UFUK; Uysal, Omer; DUNDAROZ, Mehmet Rusen; ELİBOL, BİRSEN; ÖZGEN, İLKER TOLGA; ERENBERK, UFUK; UYSAL, ÖMER
    Obesity is a multifactorial disorder resulting from the interaction between genetic, psychological, physical, environmental, and socioeconomic factors. SIRT1 gene has important effects on the regulation of adiponectin, caloric restriction, insulin sensitivity, coronary atherosclerosis, and cardiovascular diseases. The aim of this study was to investigate the association between childhood obesity and SIRT1 gene polymorphisms regarding rs7895833 A > G in the promoter region, rs7069102 C > G in intron 4, and rs2273773 C > T in exon 5 using PCR-CTPP method in 120 obese and 120 normal weight children. In this study, BMI, systolic and diastolic blood pressure, LDL cholesterol, triglyceride, and insulin levels were significantly higher and HDL-cholesterol levels were significantly lower in obese children compared to normal weight children. For rs7895833 A > G, the rate of having AG genotype and G allele was significantly higher in obese children compared to non-obese group (p T. There was no significant difference for rs7069102 C > G gene polymorphism between groups.
  • Publication
    Microperimetric Changes After Photodynamic Therapy for Central Serous Chorioretinopathy
    (2011-02-01) SENTURK, Fevzi; KARACORLU, Murat; OZDEMIR, Hakan; KARACORLU, Serra Arf; Uysal, Omer; ÖZDEMİR, MEHMET HAKAN; UYSAL, ÖMER
    PURPOSE: To evaluate the effect of half-dose verteporfin photodynamic therapy (PDT) on macular function in cases of central serous chorioretinopathy (CSC).
  • Publication
    Factors Associated with Insufficient Endometrial Sampling in Postmenopausal Women
    (2020-01-01T00:00:00Z) ATEŞ, SEDA; Karasu, Ayse Filiz Gokmen; ÇALI, HALİME; Soyman, Zeynep; UYSAL, ÖMER; ATEŞ, SEDA; ÇALI, HALİME; UYSAL, ÖMER
    Aim: To assess the risk factors associated with high rate of insufficient endometrial sampling on endometrial biopsy in postmenopausal women.