Person: UYSAL, ÖMER
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UYSAL
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ÖMER
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- PublicationMetadata onlyEffect of Different Application Techniques of All-in-One Adhesives on Microtensile Bond Strength to Sound and Caries-Affected Dentin(2015-04-03) TEKÇE, NESLİHAN; Demirci, Mustafa; Tuncer, Safa; Uysal, Omer; UYSAL, ÖMERThe aim of this study was to evaluate the microtensile bond strength of two all-in-one self-etch adhesives applied to sound and caries-affected dentin with four different application techniques. Forty extracted third molars with occlusal caries were randomly divided into four groups for G-Aenial Bond and S3 Bond: (1) according to manufacturer-s instructions; (2) with acid etching before applying adhesives; (3) doubling adhesive application time; and (4) doubling adhesive coating. Teeth were sectioned to obtain 1-mm-+/- 0.2-mm-thick dentin sticks and subjected to a tensile force. For G-Aenial Bond, doubling the time and application of two consecutive coats produced significantly higher strength than that obtained by following manufacturers- instructions and acid etching application to sound dentin. Prior acid etching and application of two consecutive coats to caries-affected dentin generated significantly higher bond strength than that using other techniques. For S3 Bond, there was no significant difference between application techniques in caries-affected dentin. For sound dentin, double-time application of S3 Bond produced significantly higher strength than application according to the manufacturers- instructions. Compared to the application according to manufacturer-s instructions, acid etching before applying adhesives, doubling application time, and doubling the coating had a positive effect on bond strength to caries-affected dentin for all-in-one adhesives.
- PublicationOpen AccessCytokine Polymorphism and HLA Genotyping in Patients with Temporal Lobe Epilepsy Related to Hippocampal Sclerosis.(2017-12-01) ALTINTAŞ, A; ÖZKARA, Ç; Sohtaoğlu, Sevindik; UZAN, M; Kekik, Çinar; Uysal, ÖMER; Savran, Oğuz; UYSAL, ÖMERObjective: Hippocampal sclerosis (HS) is the most common pathological substrate associated with mesial temporal lobe epilepsy (MTLE), where inflammatory processes are known to play an increasingly important role in the pathogenesis. To further investigate the role of the immune system, both cytokine gene polymorphisms and human leukocyte antigen (HLA) genotyping in patients with MTLE-HS were investigated. Methods: The DNA samples of 100 patients with MTLE-HS and 201 healthy individuals were genotyped for cytokines (IL-6,IL-10, TNF-α, TGF-β1 and IFN-γ) and HLA using polymerase chain reaction (PCR)-SSP and SSO methods. The results were statistically analyzed in patient and healthy control groups and then according to the presence of febrile seizures (FS) in the patient group. Results: Analysis of cytokine genotyping did not reveal any significant difference between patients with MTLE-HS and controls and patients with or without FS. However, the HLA DRB1*13 allele was found to be more frequent in the patient population after Bonferroni correction. Conclusion: This study suggests the possible role of HLA in the pathogenesis of MTLE-HS, although it failed to show any relationship with the cytokine system. However, data regarding the role of HLA are still lacking, and further studies are necessary to verify our results.
- PublicationOpen AccessCyst Fluid Carcinoembryonic Antigen Level Difference between Mucinous Cystic Neoplasms and Intraductal Papillary Mucinous Neoplasms.(2020-12-11T00:00:00Z) Köker, İbrahim Hakkı; Ünver, Nurcan; Malya, Fatma Ümit; Uysal, Ömer; Keskin, Elmas Biberci; Şentürk, Hakan; MALYA, FATMA ÜMİT; UYSAL, ÖMER; BİBERCİ KESKİN, ELMAS; ŞENTÜRK, HAKANBackground/aims: The role of cyst fluid carcinoembryonic antigen (CEA) level in differentiating mucinous pancreatic cystic lesions (PCLs) is controversial. We investigated the role of cyst fluid CEA in differentiating low-risk (LR)-intraductal papillary mucinous neoplasms (IPMNs) from high-risk (HR)-IPMNs and LR-mucinous cystic neoplasms (MCNs). Methods: This was a retrospective study of 466 patients with PCLs who underwent endoscopic ultrasound-guided fine-needleaspiration over a 7-year period. On histology, low-grade dysplasia and intermediate-grade dysplasia were considered LR, whereas high-grade dysplasia and invasive carcinoma were considered HR. Results: Data on cyst fluid CEA levels were available for 50/102 mucinous PCLs with definitive diagnoses. The median CEA (range) levels were significantly higher in HR cysts than in LR cysts (2,624 [0.5-266,510] ng/mL vs. 100 [16.8-53,445]ng/mL, p=0.0012). The area under the receiver operating characteristic curve (AUROC) was 0.930 (95% confidence interval [CI], 0.5-0.8; p<0.001) for differentiating LR-IPMNs from LR-MCNs. The AUROC was 0.921 (95% CI, 0.823-1.000; p<0.001) for differentiating LR-IPMNs from HR-IPMNs. Both had a CEA cutoff level of >100ng/mL, with a negative predictive value (NPV) of 100%. Conclusion: Cyst fluid CEA levels significantly vary between LR-IPMNs, LR-MCNs, and HR-IPMNs. A CEA cutoff level of >100ng/mL had a 100% NPV in differentiating LR-IPMNs from LR-MCNs and HR-IPMNs.
- PublicationOpen AccessEffects of ischemic preconditioning and iloprost on myocardial ischemia-reperfusion damage in rats(2013-01-01) Ay, YASİN; Kara, Ibrahim; Aydin, CEMALETTİN; TEKER, Melike Elif; Senol, Serkan; Inan, BEKİR; BASEL, Halil; Uysal, Omer; Zeybek, RAHMİ; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY; İNAN, BEKİR; UYSAL, ÖMER; ZEYBEK, RAHMİThis study investigates the effects of cardiac ischemic preconditioning and iloprost on reperfusion damage in rats with myocardial ischemia/reperfusion. 38 male Wistar Albino rats used in this study were divided into 5 groups. The control group (Group 1) (n=6), ischemia/reperfusion (IR) group (Group 2) (n=8), cardiac ischemic preconditioning (CIP) group (Group 3) (n=8), iloprost (ILO) group (Group 4) (n=8), and cardiac ischemic preconditioning + iloprost (CIP+ILO) group (Group 5) (n=8). Pre-ischemia, 15 minutes post-ischemia, 45 minutes post-reperfusion, mean blood pressure (MBP), and heart rates (HR) were recorded. The rate-pressure product (RPP) was calculated. Post-reperfusion plasma creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH), troponin (cTn) vlaues, and infarct size/area at risk (IS/AAR) were calculated from myocardial tissue samples. Arrhythmia and ST segment elevations were evaluated during the ischemia and reperfusion stages. Although the MBP, HR, RPP values, biochemical parameters of CK-MB and LDH levels, IS/AAR rates, ST segment elevation values were found to be similar in CIP and CIP+ILO groups and the IR and ILO groups (p>0.05), CIP-containing group values had a positively meaningful difference (p<0.05) compared with the IR and ILO group. While mild-moderate findings of damage were observed in Group 3 and Group 5, severely findings of damage were releaved in Group 2 and Group 4. The arrhythmia score of the ILO group was meaningfully lower (F: 41.4, p<0.001) than the IR group. We can conclude that the effects of myocardial reperfusion damage can be reduced by cardiac ischemic preconditioning, intravenous iloprost reduced the incidence of ventricular arrhythmia associated with reperfusion, and its use with CIP caused no additional changes.
- PublicationMetadata onlyThe Simplest way of assessing memory and attention function in daily clinical practice(2016-01-01) Arikan, Mehmet Kemal; Tarhan, Nevzat; UYSAL, ÖMER; Kupcuoglu, Serra; GUNAY, Barlas; Küçük, Zeynep; UYSAL, ÖMER
- PublicationMetadata onlyFactors Associated with Insufficient Endometrial Sampling in Postmenopausal Women(2020-01-01T00:00:00Z) ATEŞ, SEDA; GÖKMEN KARASU, AYŞE FİLİZ; ÇALI, HALİME; SOYMAN, ZEYNEP; UYSAL, ÖMER; ATEŞ, SEDA; GÖKMEN KARASU, AYŞE FİLİZ; ÇALI, HALİME; UYSAL, ÖMER
- PublicationOpen AccessThe Correlation Between Footprint and Radiographic Measurements in Flatfoot(2012-12-01) Gun, Kerem; Saridogan, Merih; Uysal, Omer; UYSAL, ÖMERObjective: The aim of this study was to determine the correlation between 3 different footprint measurement procedures and 3 different radiological assessment methods in the diagnosis of pes planus.
- PublicationMetadata onlyRelationships between markers of inflammation, neutrophil-to-lymphocyte ratio and syntax severity score in early phase of acute coronary syndrome(2017-03-01) METIN, HÜSEYİN; ISMAILOGLU, ZİYA; ISMAILOVA, MEDİNE; AKBAY, DURSUN; UYSAL, ÖMER; GÜLEN, BEDİA; SÖNMEZ, ERTAN; UYSAL, ÖMER; GÜLEN, BEDİA; SÖNMEZ, ERTAN
- PublicationOpen AccessDiagnostic performance of the RT-qPCR method targeting 85B mRNA in the diagnosis of pulmonary Mycobacterium tuberculosis infection(2018-09-01T00:00:00Z) Demirci, Mehmet; Saribas, Suat; Ozer, Nigar; TOPRAK, Sezer; CAGLAR, Emel; ORTAKOYLU, Gonenc; Yuksel, PELİN; Ayaz, Gulsel; Tokman, Hrisi B.; Uysal, Omer; Dinc, HARİKA ÖYKÜ; ZİVER, Tevhide; Kocazeybek, Bekir; YÜKSEL MAYDA, PELİN; UYSAL, ÖMER; DİNÇ, HARİKA ÖYKÜBackground: Several nucleic acid amplification techniques (IS6110, 16S rRNA, and 85B mRNA) were developed for the rapid, direct detection of Mycobacterium tuberculosis. We aimed to assess the diagnostic performance of 85B mRNA-based RT-qPCR by comparing with the real-time PCR COBAS TagMan MTB Kit while using the BACTEC MGIT 960 method as the gold standard.
- PublicationMetadata onlyThe association between polymorphism in HLA-A, HLA-B, HLA-DR and DQ genes of gastric cancer and duodenal ulcer patients with CagL positivity among CagA-positive Helicobacter pylori strains(2019-09-01) Kocazeybek, B. S.; Ozbey, D. K.; Gareayaghi, N.; UYSAL, ÖMER; UYSAL, ÖMER