Person: TOK, OLGU ENİS
Search Results
Effects of beta-glucan on protection of young and aged rats from renal ischemia and reperfusion injury
2016-01-01, ESREFOGLU, MUKADDES, Tok, OLGU ENİS, AYDIN, M. S., OZER, O. F., SELEK, S., Iraz, M., EŞREFOĞLU, MUKADDES, TOK, OLGU ENİS, ÖZER, ÖMER FARUK, SELEK, ŞAHABETTİN
BACKGROUND: Ischemia reperfusion injury is one of the leading causes of acute renal failure which is a common clinical event leading to development of chronic kidney disease and a high mortality; especially in elderly people. beta-glucans are glucose polymer groups with free-radical scavenger, macrophage activator, and immune defense inducer functions. We designed this study to determine the possible protective effects of beta-glucan against renal ischemia reperfusion injury comparatively in young and aged rats.
Therapeutic effects of melatonin and quercetin in improvement of hepatic steatosis in rats through supression of oxidative damage
2017-01-01, ESREFOGLU, MUKADDES, ÇETİN, AYMELEK, TASLIDERE, ELİF, Elbe, H., ATEŞ, BURHAN, Tok, OLGU ENİS, AYDIN, M. S., EŞREFOĞLU, MUKADDES, TAŞLIDERE, ELİF, TOK, OLGU ENİS
BACKGROUND: Non-alcoholic steatohepatitis, a cause of cirrhosis, is characterized by fatty infiltration of the liver, inflammation, hepatocellular damage and fibrosis. The aim of the present study was to investigate the effects of melatonin and quercetin on CCl4-induced steatosis characterized by fatty infiltration of the liver, inflammation, hepatocellular damage and fibrosis.